Impaired activation of Notch-1 signaling hinders repair processes of bronchial epithelial cells exposed to cigarette smoke

Autor: Di Sano, C., D'Anna, C., Ferraro, M., Chiappara, G., Sangiorgi, C., Di Vincenzo, S., Bertani, A., Vitulo, P., Bruno, A., Dino, P., Pace, E. ^*

Publikováno v: In Toxicology Letters 15 June 2020 326:61-69

Notch‐1 signaling activation sustains overexpression of interleukin 33 in the epithelium of nasal polyps.

Autor: Chiappara, G., Sciarrino, S., Di Sano, C., Gallina, S., Speciale, R., Lorusso, F., Di Vincenzo, S., D'Anna, C., Bruno, A., Gjomarkaj, M., Pace, E.

Publikováno v: Journal of Cellular Physiology; Apr2019, Vol. 234 Issue 4, p4582-4596, 15p

Cigarette smoke upregulates Notch-1 signaling pathway and promotes lung adenocarcinoma progression.

Autor: Chiappara G; Institute for Biomedical Research and Innovation (IRIB), National Research Council of Italy (CNR), Palermo, Italy., Di Vincenzo S; Institute for Biomedical Research and Innovation (IRIB), National Research Council of Italy (CNR), Palermo, Italy., Sangiorgi C; Institute for Biomedical Research and Innovation (IRIB), National Research Council of Italy (CNR), Palermo, Italy., Di Sano C; Institute for Biomedical Research and Innovation (IRIB), National Research Council of Italy (CNR), Palermo, Italy., D'Anna C; Institute for Biomedical Research and Innovation (IRIB), National Research Council of Italy (CNR), Palermo, Italy., Zito G; Ri.Med Foundation, Palermo, Italy., Cipollina C; Ri.Med Foundation, Palermo, Italy., Vitulo P; Mediterranean Institute for Transplantation and Highly Specialized Therapies (ISMETT), Department for the Treatment and Study of Cardiothoracic Diseases and Cardiothoracic Transplantation, IRCCS ISMETT, Palermo, Italy., Bertani A; Mediterranean Institute for Transplantation and Highly Specialized Therapies (ISMETT), Department for the Treatment and Study of Cardiothoracic Diseases and Cardiothoracic Transplantation, IRCCS ISMETT, Palermo, Italy., Pace E; Institute for Biomedical Research and Innovation (IRIB), National Research Council of Italy (CNR), Palermo, Italy. Electronic address: elisabetta.pace@irib.cnr.it.

Publikováno v: Toxicology letters [Toxicol Lett] 2022 Feb 01; Vol. 355, pp. 31-40. Date of Electronic Publication: 2021 Nov 05.

Role of chronic exsposure to cigarette smoke on endoglin/CD105 expression in airway epithelium

Autor: Gagliardo, R, Montalbano, AM, Marchese, R, Albano, GD, Anzalone, G, Chiappara, G, Paglino, G, Profita, M., BUCCHIERI, Fabio, RAPPA, Francesca, FUCARINO, Alberto Giuseppe, Tralongo, Pietro

Dysregulation of airway epithelial cell function related to cigarette smoke exposure plays an important role in the pathophysiology of COPD and is associated to tissue damage and disease severity. CD105 is a component of the receptor complex of TGF-�

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3658::013ef69a775c1c31aec8999bb5c196ea
http://hdl.handle.net/10447/149108

Cilomilast Modulates Rhinovirus-Induced Airway Epithelial ICAM-1 Expression and IL-6, CXCL8 and CCL5 Production.

Autor: Zhu, Jie¹ (AUTHOR) jiezhu57@gmail.com, Edwards, Michael R.¹ (AUTHOR) michael.edwards@imperial.ac.uk, Message, Simon D.² (AUTHOR) simon.message@glos.nhs.uk, Stanciu, Luminita A.¹ (AUTHOR) s.johnston@imperial.ac.uk, Johnston, Sebastian L.¹ (AUTHOR), Jeffery, Peter K.¹ (AUTHOR) p.jeffery@imperial.ac.uk

Publikováno v: Pharmaceuticals (14248247). Nov2024, Vol. 17 Issue 11, p1554. 19p.