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pro vyhledávání: '"Chiang, CWK"'
XQ was supported by a PhD scholarship from the China Scholarship Council and now is supported by International Postdoctoral Exchange Fellowship Program (Talent-Introduction Program) from China Postdoc Council. CWKC is supported in part by National In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93431430ff3bbca815d257e4f911c863
https://doi.org/10.1101/2021.05.27.445973
https://doi.org/10.1101/2021.05.27.445973
Autor:
Chiang Cwk, David Schlessinger, Masakazu Akiyama, Yoichiro Kamatani, Yukinori Okada, Francesco Cucca, Kazuyoshi Ishigaki, Maogen Chen, Carlo Sidore
Adult height was one of the earliest putative examples of polygenic adaptation in human. By constructing polygenic height scores using effect sizes and frequencies from hundreds of genomic loci robustly associated with height, it was reported that No
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::592955194df4f4c48519364a02ba36e9
Autor:
Iain Mathieson, Joel N. Hirschhorn, Mark J. Daly, Andrea Ganna, Benjamin M. Neale, David Reich, Alicia R. Martin, Robert Maier, Alex Bloemendal, Nick Patterson, Michael C. Turchin, Chiang Cwk, Sunyaev, Mashaal Sohail
Genetic predictions of height differ among human populations and these differences are too large to be explained by genetic drift. This observation has been interpreted as evidence of polygenic adaptation. Differences across populations were detected
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49d4329d780c251b4b59f98248896cad
Autor:
Winkler, TW, Justice, AE, Graff, M, Barata, L, Feitosa, MF, Chu, S, Czajkowski, J, Esko, T, Fall, T, Kilpeläinen, TO, Lu, Y, Mägi, R, Mihailov, E, Pers, TH, Rüeger, S, Teumer, A, Ehret, GB, Ferreira, T, Heard-Costa, NL, Karjalainen, J, Lagou, V, Mahajan, A, Neinast, MD, Prokopenko, I, Simino, J, Teslovich, TM, Jansen, R, Westra, HJ, White, CC, Absher, D, Ahluwalia, TS, Ahmad, S, Albrecht, E, Alves, AC, Bragg-Gresham, JL, de Craen, AJM, Bis, JC, Bonnefond, A, Boucher, G, Cadby, G, Cheng, YC, Chiang, CWK, Delgado, G, Demirkan, A, Dueker, N, Eklund, N, Eiriksdottir, G, Eriksson, J, Feenstra, B, Fischer, K, Frau, F, Galesloot, TE, Geller, F, Goel, A, Gorski, M, Grammer, TB, Gustafsson, S, Haitjema, S, Hottenga, JJ, Huffman, JE, Jackson, AU, Jacobs, KB, Johansson, Å, Kaakinen, M, Kleber, ME
Publikováno v:
Winkler, TW; Justice, AE; Graff, M; Barata, L; Feitosa, MF; Chu, S; et al.(2015). The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. PLoS Genetics, 11(10), 1-42. doi: 10.1371/journal.pgen.1005378. UCLA: Retrieved from: http://www.escholarship.org/uc/item/2786j7cf
Genome-wide association studies (GWAS) have identified more than 100 genetic variants contributing to BMI, a measure of body size, or waist-to-hip ratio (adjusted for BMI, WHRadjBMI), a measure of body shape. Body size and shape change as people grow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::9b23025d95f7aaec1c8d4c9ee5b1f2a2
http://www.escholarship.org/uc/item/2786j7cf
http://www.escholarship.org/uc/item/2786j7cf
Akademický článek
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Autor:
Metayer C; Division of Epidemiology, School of Public Health, University of California, Berkeley, Berkeley, California., Spector LG; Division of Epidemiology and Clinical Research, Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota., Scheurer ME; Division of Hematology-Oncology, Department of Pediatrics, Baylor College of Medicine, Houston, Texas.; Texas Children's Cancer and Hematology Centers, Texas Children's Hospital, Houston, Texas., Jeon S; Center for Genetic Epidemiology, Department of Population and Public Health Sciences, University of Southern California, Los Angeles, California., Scott RJ; Faculty of Medicine and Health, School of Biomedical Science and Pharmacy, Hunter Medical Research Institute, University of Newcastle, New Lambton, Australia.; Division of Molecular Medicine, NSW Health Pathology, John Hunter Hospital, Newcastle, Australia., Takagi M; Department of Pediatrics and Developmental Biology, Tokyo Medical and Dental University, Tokyo, Japan., Clavel J; Inserm UMR1153, Epidemiology of Childhood and Adolescent Cancers (EPICEA) Team, Université Paris Cité and Université Sorbonne Paris Nord, Inserm, INRAE, Center for Research in Epidemiology and Statistics (CRESS), Paris, France.; French National Registry of Childhood Cancers, RNHE, Hôpital Paul Brousse, Groupe Hospitalier Universitaire Paris-Sud, AP-HP, Villejuif, France.; RNTSE, CHRU de Nancy, Vandoeuvre-lès-Nancy, France., Manabe A; Department of Pediatrics, Hokkaido University, Sapporo, Japan., Ma X; Department of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, Connecticut., Hailu EM; Division of Epidemiology, School of Public Health, University of California, Berkeley, Berkeley, California., Lupo PJ; Division of Hematology-Oncology, Department of Pediatrics, Baylor College of Medicine, Houston, Texas.; Texas Children's Cancer and Hematology Centers, Texas Children's Hospital, Houston, Texas., Urayama KY; Department of Social Medicine, National Center for Child Health and Development, Tokyo, Japan.; Graduate School of Public Health, St. Luke's International University, Tokyo, Japan., Bonaventure A; Inserm UMR1153, Epidemiology of Childhood and Adolescent Cancers (EPICEA) Team, Université Paris Cité and Université Sorbonne Paris Nord, Inserm, INRAE, Center for Research in Epidemiology and Statistics (CRESS), Paris, France., Kato M; Department of Pediatrics, The University of Tokyo, Tokyo, Japan., Meirhaeghe A; Université de Lille, INSERM, Centre Hospitalier Universitaire de Lille, Institut Pasteur de Lille, U1167 - RID-AGE - Facteurs de Risque et Déterminants Moléculaires des Maladies Liées au Vieillissement, Lille, France., Chiang CWK; Center for Genetic Epidemiology, Department of Population and Public Health Sciences, University of Southern California, Los Angeles, California., Morimoto LM; Division of Epidemiology, School of Public Health, University of California, Berkeley, Berkeley, California., Wiemels JL; Center for Genetic Epidemiology, Department of Population and Public Health Sciences, University of Southern California, Los Angeles, California.
Publikováno v:
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology [Cancer Epidemiol Biomarkers Prev] 2024 Sep 03; Vol. 33 (9), pp. 1248-1252.
Autor:
Cahoon JL; Center for Genetic Epidemiology, Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, Los Angeles, CA 90033, USA; Department of Quantitative and Computational Biology, University of Southern California, Los Angeles, Los Angeles, CA 90089, USA; Department of Computer Science, University of Southern California, Los Angeles, Los Angeles, CA 90089, USA., Rui X; Center for Genetic Epidemiology, Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, Los Angeles, CA 90033, USA., Tang E; Department of Quantitative and Computational Biology, University of Southern California, Los Angeles, Los Angeles, CA 90089, USA., Simons C; Department of Quantitative and Computational Biology, University of Southern California, Los Angeles, Los Angeles, CA 90089, USA., Langie J; Center for Genetic Epidemiology, Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, Los Angeles, CA 90033, USA., Chen M; Center for Genetic Epidemiology, Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, Los Angeles, CA 90033, USA., Lo YC; Center for Genetic Epidemiology, Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, Los Angeles, CA 90033, USA., Chiang CWK; Center for Genetic Epidemiology, Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, Los Angeles, CA 90033, USA; Department of Quantitative and Computational Biology, University of Southern California, Los Angeles, Los Angeles, CA 90089, USA; Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, Los Angeles, CA 90033, USA. Electronic address: charleston.chiang@med.usc.edu.
Publikováno v:
American journal of human genetics [Am J Hum Genet] 2024 May 02; Vol. 111 (5), pp. 979-989. Date of Electronic Publication: 2024 Apr 10.
Autor:
de Smith AJ; Center for Genetic Epidemiology, Department of Population and Public Health Sciences, University of Southern California Keck School of Medicine, Los Angeles, CA 90033, USA; USC Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90033, USA. Electronic address: desmith@usc.edu., Wahlster L; Division of Hematology/Oncology, Boston Children's Hospital and Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Jeon S; Center for Genetic Epidemiology, Department of Population and Public Health Sciences, University of Southern California Keck School of Medicine, Los Angeles, CA 90033, USA; USC Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90033, USA., Kachuri L; Department of Epidemiology and Population Health, Stanford University School of Medicine, Stanford, CA 94305, USA., Black S; Division of Hematology/Oncology, Boston Children's Hospital and Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Langie J; Center for Genetic Epidemiology, Department of Population and Public Health Sciences, University of Southern California Keck School of Medicine, Los Angeles, CA 90033, USA; USC Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90033, USA., Cato LD; Division of Hematology/Oncology, Boston Children's Hospital and Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Nakatsuka N; New York Genome Center, New York, NY 10013, USA., Chan TF; Center for Genetic Epidemiology, Department of Population and Public Health Sciences, University of Southern California Keck School of Medicine, Los Angeles, CA 90033, USA; USC Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90033, USA., Xia G; GMU-GIBH Joint School of Life Sciences, The Guangdong-Hong Kong-Macau Joint Laboratory for Cell Fate Regulation and Diseases, Guangzhou National Laboratory, Guangzhou Medical University, Guangzhou, China., Mazumder S; Division of Hematology/Oncology, Boston Children's Hospital and Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Yang W; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Gazal S; Center for Genetic Epidemiology, Department of Population and Public Health Sciences, University of Southern California Keck School of Medicine, Los Angeles, CA 90033, USA; USC Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90033, USA., Eng C; Department of Medicine, Institute for Human Genetics, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Bioengineering and Biotherapeutic Sciences, University of California, San Francisco, San Francisco, CA 94143, USA., Hu D; Department of Medicine, Institute for Human Genetics, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94143, USA., Burchard EG; Department of Medicine, Institute for Human Genetics, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Bioengineering and Biotherapeutic Sciences, University of California, San Francisco, San Francisco, CA 94143, USA., Ziv E; Department of Medicine, Institute for Human Genetics, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94143, USA., Metayer C; School of Public Health, University of California, Berkeley, Berkeley, CA 94720, USA., Mancuso N; Center for Genetic Epidemiology, Department of Population and Public Health Sciences, University of Southern California Keck School of Medicine, Los Angeles, CA 90033, USA; USC Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90033, USA., Yang JJ; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Ma X; Yale School of Public Health, New Haven, CT 06520, USA., Wiemels JL; Center for Genetic Epidemiology, Department of Population and Public Health Sciences, University of Southern California Keck School of Medicine, Los Angeles, CA 90033, USA; USC Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90033, USA., Yu F; Division of Hematology/Oncology, Boston Children's Hospital and Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; GMU-GIBH Joint School of Life Sciences, The Guangdong-Hong Kong-Macau Joint Laboratory for Cell Fate Regulation and Diseases, Guangzhou National Laboratory, Guangzhou Medical University, Guangzhou, China., Chiang CWK; Center for Genetic Epidemiology, Department of Population and Public Health Sciences, University of Southern California Keck School of Medicine, Los Angeles, CA 90033, USA; USC Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90033, USA., Sankaran VG; Division of Hematology/Oncology, Boston Children's Hospital and Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. Electronic address: sankaran@broadinstitute.org.
Publikováno v:
Cell genomics [Cell Genom] 2024 Apr 10; Vol. 4 (4), pp. 100526. Date of Electronic Publication: 2024 Mar 26.
Autor:
Hangai M; Department of Social Medicine, National Center for Child Health and Development, Tokyo, Japan; Department of Pediatrics, The University of Tokyo, Tokyo., Kawaguchi T; Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto., Takagi M; Department of Pediatrics and Developmental Biology, Tokyo Medical and Dental University, Tokyo., Matsuo K; Division of Cancer Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya., Jeon S; Center for Genetic Epidemiology, Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles., Chiang CWK; Center for Genetic Epidemiology, Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, USA; Department of Quantitative and Computational Biology, University of Southern California, Los Angeles., Dewan AT; Department of Chronic Disease Epidemiology, Yale School of Public Health, New Haven., De Smith AJ; Center for Genetic Epidemiology, Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles., Imamura T; Department of Pediatrics, Kyoto Prefectural University of Medicine, Kyoto., Okamoto Y; Department of Pediatrics, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima., Saito AM; Clinical Research Center, National Hospital Organization Nagoya Medical Center, Nagoya., Deguchi T; Children's Cancer Center, National Center for Child Health and Development, Tokyo., Kubo M; Laboratory for Genotyping Development, RIKEN Center for Integrative Medical Sciences, Kanagawa., Tanaka Y; Division of Medicinal Safety Science, National Institute of Health Sciences, Kawasaki., Ayukawa Y; Department of Social Medicine, National Center for Child Health and Development, Tokyo., Hori T; Department of Pediatrics, Aichi Medical University Hospital, Nagoya., Ohki K; Department of Pediatric Hematology and Oncology Research, National Center for Child Health and Development, Tokyo., Kiyokawa N; Department of Pediatric Hematology and Oncology Research, National Center for Child Health and Development, Tokyo., Inukai T; Department of Pediatrics, University of Yamanashi, Yamanashi., Arakawa Y; Department of Hematology/Oncology, Saitama Children's Medical Center, Saitama., Mori M; Department of Hematology/Oncology, Saitama Children's Medical Center, Saitama., Hasegawa D; Department of Pediatrics, St. Luke's International Hospital, Tokyo., Tomizawa D; Children's Cancer Center, National Center for Child Health and Development, Tokyo., Fukushima H; Department of Child Health, Faculty of Medicine, University of Tsukuba, Tsukuba., Yuza Y; Department of Hematology/Oncology, Tokyo Metropolitan Children's Medical Center, Tokyo., Noguchi Y; Department of Pediatrics, Japanese Red Cross Narita Hospital, Chiba., Taneyama Y; Department of Hematology/Oncology, Chiba Children's Hospital, Chiba., Ota S; Department of Pediatrics, Teikyo University Chiba Medical Center, Chiba., Goto H; Division of Hematology/Oncology, Kanagawa Children's Medical Center, Yokohama., Yanagimachi M; Division of Hematology/Oncology, Kanagawa Children's Medical Center, Yokohama., Keino D; Division of Hematology/Oncology, Kanagawa Children's Medical Center, Yokohama., Koike K; Division of Pediatric Hematology and Oncology, Ibaraki Children's Hospital, Mito., Toyama D; Division of Pediatrics, Showa University Fujigaoka Hospital, Yokohama., Nakazawa Y; Department of Pediatrics, Shinshu University School of Medicine, Matsumoto., Nakamura K; Department of Pediatrics, Teikyo University Hospital, Tokyo., Moriwaki K; Department of Pediatrics, Saitama Medical Center, Saitama Medical University, Saitama., Sekinaka Y; Department of Pediatrics, National Defense Medical College, Saitama., Morita D; Department of Pediatrics, Shinshu University School of Medicine, Matsumoto., Hirabayashi S; Department of Pediatrics, Hokkaido University, Sapporo., Hosoya Y; Department of Pediatrics, St. Luke's International Hospital, Tokyo., Yoshimoto Y; Department of Pediatrics, National Center for Global Health and Medicine, Tokyo., Yoshihara H; Department of Pediatrics, St. Luke's International Hospital, Tokyo., Ozawa M; Department of Pediatrics, St. Luke's International Hospital, Tokyo., Kobayashi S; Department of Social Medicine, National Center for Child Health and Development, Tokyo., Morisaki N; Department of Social Medicine, National Center for Child Health and Development, Tokyo., Gyeltshen T; Graduate School of Public Health, St. Luke's International University, Tokyo., Takahashi O; Graduate School of Public Health, St. Luke's International University, Tokyo., Okada Y; Department of Statistical Genetics, Graduate School of Medicine, Osaka University, Osaka, Japan; Department of Genome Informatics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan; Laboratory for Systems Genetics, RIKEN Center for Integrative Medical Sciences, Kanagawa., Matsuda M; Department of Human Genetics and Disease Diversity, Tokyo Medical Dental University, Tokyo., Tanaka T; Department of Human Genetics and Disease Diversity, Tokyo Medical Dental University, Tokyo., Inazawa J; Department of Molecular Cytogenetics, Tokyo Medical and Dental University, Tokyo., Takita J; Department of Pediatrics, Kyoto University Graduate School of Medicine, Kyoto., Ishida Y; Pediatric Medical Center, Ehime Prefectural Central Hospital, Matsuyama., Ohara A; Department of Pediatrics, Toho University, Tokyo., Metayer C; School of Public Health, University of California Berkeley, Berkeley, California., Wiemels JL; Center for Genetic Epidemiology, Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles., Ma X; Department of Chronic Disease Epidemiology, Yale School of Public Health, New Haven., Mizutani S; Department of Pediatrics and Developmental Biology, Tokyo Medical and Dental University, Tokyo., Koh K; Department of Hematology/Oncology, Saitama Children's Medical Center, Saitama., Momozawa Y; Laboratory for Genotyping Development, RIKEN Center for Integrative Medical Sciences, Kanagawa., Horibe K; Clinical Research Center, National Hospital Organization Nagoya Medical Center, Nagoya., Matsuda F; Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto., Kato M; Department of Pediatrics, The University of Tokyo, Tokyo., Manabe A; Department of Pediatrics, Hokkaido University, Sapporo., Urayama KY; Department of Social Medicine, National Center for Child Health and Development, Tokyo, Japan; Graduate School of Public Health, St. Luke's International University, Tokyo. kevurayama@gmail.com.
Publikováno v:
Haematologica [Haematologica] 2024 Apr 01; Vol. 109 (4), pp. 1247-1252. Date of Electronic Publication: 2024 Apr 01.
Autor:
Brandt DYC; Department of Genetics Evolution and Environment, University College London, London, UK., Huber CD; Department of Biology, Pennsylvania State University, University Park, PA, USA., Chiang CWK; Center for Genetic Epidemiology, Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.; Department of Quantitative and Computational Biology, University of Southern California, Los Angeles, CA, USA., Ortega-Del Vecchyo D; Laboratorio Internacional de Investigación sobre el Genoma Humano, Universidad Nacional Autónoma De México, Querétaro, Querétaro, Mexico.
Publikováno v:
Genome biology and evolution [Genome Biol Evol] 2024 Feb 01; Vol. 16 (2).