Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Chian‐Shiu Chien"'
Autor:
Yueh Chien, Xuan-Yang Huang, Aliaksandr A. Yarmishyn, Chian-Shiu Chien, Yu-Hao Liu, Yu-Jer Hsiao, Yi-Ying Lin, Wei-Yi Lai, Ssu-Cheng Huang, Meng-Shiue Lee, Shih-Hwa Chiou, Yi-Ping Yang, Guang-Yuh Chiou
Publikováno v:
Virus Research, Vol 345, Iss , Pp 199391- (2024)
Coronaviruses (CoVs) are enveloped single-stranded RNA viruses that predominantly attack the human respiratory system. In recent decades, several deadly human CoVs, including SARS-CoV, SARS-CoV-2, and MERS-CoV, have brought great impact on public hea
Externí odkaz:
https://doaj.org/article/62ccca49f93746578f97bb8f082a90c0
Autor:
An Xu, Mo Liu, Mo-Fan Huang, Yang Zhang, Ruifeng Hu, Julian A. Gingold, Ying Liu, Dandan Zhu, Chian-Shiu Chien, Wei-Chen Wang, Zian Liao, Fei Yuan, Chih-Wei Hsu, Jian Tu, Yao Yu, Taylor Rosen, Feng Xiong, Peilin Jia, Yi-Ping Yang, Danielle A. Bazer, Ya-Wen Chen, Wenbo Li, Chad D. Huff, Jay-Jiguang Zhu, Francesca Aguilo, Shih-Hwa Chiou, Nathan C. Boles, Chien-Chen Lai, Mien-Chie Hung, Zhongming Zhao, Eric L. Van Nostrand, Ruiying Zhao, Dung-Fang Lee
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
The dysregulation of the m6A epitranscriptomic networks have been reported to contribute to the development of gliomas. Here, the authors utilize induced pluripotent stem cell-derived astrocytes with a p53 mutation and demonstrate that mutant p53 upr
Externí odkaz:
https://doaj.org/article/e94f230ab56e49dfb83c91e1ccf71c9f
Autor:
Aliaksandr A. Yarmishyn, Yi-Ping Yang, Kai-Hsi Lu, Yi-Chen Chen, Yueh Chien, Shih-Jie Chou, Ping-Hsing Tsai, Hsin-I. Ma, Chian-Shiu Chien, Ming-Teh Chen, Mong-Lien Wang
Publikováno v:
Cancer Cell International, Vol 20, Iss 1, Pp 1-15 (2020)
Abstract Background Glioblastoma (GBM) is the most lethal brain tumor characterized by high morbidity and limited treatment options. Tumor malignancy is usually associated with the epigenetic marks, which coordinate gene expression to ascertain relev
Externí odkaz:
https://doaj.org/article/6dc9a28c351b42c8aa20ac596e330802
Autor:
Chian-Shiu Chien, Yueh Chien, Yi-Ying Lin, Ping-Hsing Tsai, Shih-Jie Chou, Aliaksandr A. Yarmishyn, Elham Rastegari, Ting-Xian Wang, Hsin-Bang Leu, Yi-Ping Yang, Mong-Lien Wang, Ying-Chun Jheng, Henkie Isahwan Ahmad Mulyadi Lai, Lo-Jei Ching, Teh-Ia Huo, Jong-Yuh Cherng, Chien-Ying Wang
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Non-viral gene delivery holds promises for treating inherited diseases. However, the limited cloning capacity of plasmids may hinder the co-delivery of distinct genes to the transfected cells. Previously, the conjugation of maleimide-functionalized p
Externí odkaz:
https://doaj.org/article/06e7ba69acc949cfa46f67b06f9229a6
Autor:
Yanwen Liang, Mong-Lien Wang, Chian-Shiu Chien, Aliaksandr A. Yarmishyn, Yi-Ping Yang, Wei-Yi Lai, Yung-Hung Luo, Yi-Tsung Lin, Yann-Jang Chen, Pei-Ching Chang, Shih-Hwa Chiou
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
A sudden outbreak of COVID-19 caused by a novel coronavirus, SARS-CoV-2, in Wuhan, China in December 2019 quickly grew into a global pandemic, putting at risk not only the global healthcare system, but also the world economy. As the disease continues
Externí odkaz:
https://doaj.org/article/deea897f79184220a0c2ed06741a9aa4
Autor:
Shih‐Jie Chou, Peng Yang, Qian Ban, Yi‐Ping Yang, Mong‐Lien Wang, Chian‐Shiu Chien, Shih‐Jen Chen, Na Sun, Yazhen Zhu, Hongtao Liu, Wenqiao Hui, Tai‐Chi Lin, Fang Wang, Ryan Yue Zhang, Viet Q. Nguyen, Wenfei Liu, Mengxiang Chen, Steve J. Jonas, Paul S. Weiss, Hsian‐Rong Tseng, Shih‐Hwa Chiou
Publikováno v:
Advanced Science, Vol 7, Iss 10, Pp n/a-n/a (2020)
Abstract The homology‐independent targeted integration (HITI) strategy enables effective CRISPR/Cas9‐mediated knockin of therapeutic genes in nondividing cells in vivo, promising general therapeutic solutions for treating genetic diseases like X
Externí odkaz:
https://doaj.org/article/73b313974d854f8cbb56eec82f8ba8d4
Autor:
Wei-Lien Tseng, Shih-Jie Chou, Huai-Chih Chiang, Mong-Lien Wang, Chian-Shiu Chien, Kuan-Hsuan Chen, Hsin-Bang Leu, Chien-Ying Wang, Yuh-Lih Chang, Yung-Yang Liu, Yuh-Jyh Jong, Shinn-Zong Lin, Shih-Hwa Chiou, Shing-Jong Lin, Wen-Chung Yu
Publikováno v:
Cell Transplantation, Vol 26 (2017)
Fabry disease (FD) is an X-linked inherited lysosomal storage disease caused by α-galactosidase A (GLA) deficiency. Progressive intracellular accumulation of globotriaosylceramide (Gb3) is considered to be pathogenically responsible for the phenotyp
Externí odkaz:
https://doaj.org/article/23c8f644a4d448c19f9704cc3a96b400
Autor:
Yi-Ping Yang, Phan Nguyen Nhi Nguyen, Tai-Chi Lin, Aliaksandr A. Yarmishyn, Wun-Syuan Chen, De-Kuang Hwang, Guang-Yuh Chiou, Tzu-Wei Lin, Chian-Shiu Chien, Ching-Yao Tsai, Shih-Hwa Chiou, Shih-Jen Chen, Chi-Hsien Peng, Chih-Chien Hsu
Publikováno v:
Cells, Vol 8, Iss 6, p 625 (2019)
The mitochondrial genetic disorder, Leber’s hereditary optic neuropathy (LHON), is caused by a mutation in MT-ND4 gene, encoding NADH dehydrogenase subunit 4. It leads to the progressive death of retinal ganglion cells (RGCs) and causes visual impa
Externí odkaz:
https://doaj.org/article/f60760db58534120996b22c7f23b89cd
Autor:
Hui-Yung Song, Chian-Shiu Chien, Aliaksandr A. Yarmishyn, Shih-Jie Chou, Yi-Ping Yang, Mong-Lien Wang, Chien-Ying Wang, Hsin-Bang Leu, Wen-Chung Yu, Yuh-Lih Chang, Shih-Hwa Chiou
Publikováno v:
Cells, Vol 8, Iss 4, p 327 (2019)
Fabry disease (FD) is a rare inherited disorder characterized by a wide range of systemic symptoms; it is particularly associated with cardiovascular and renal problems. Enzyme replacement therapy and pharmacological chaperone migalastat are the only
Externí odkaz:
https://doaj.org/article/c8f309761ee54db78f189bbab02b451d
Autor:
Chih-Hung Chiang, Wai-Wah Wu, Hsin-Yang Li, Yueh Chien, Cho-Chin Sun, Chi-Hsien Peng, Alex Tong-Long Lin, Chi-Shuan Huang, Ying-Hsiu Lai, Shih-Hwa Chiou, Shuen-Iu Hung, Yuh-Lih Chang, Yuan-Tzu Lan, Dean-Mo Liu, Chian-Shiu Chien, Teh-Ia Huo, Shou-Dong Lee, Chien-Ying Wang
Publikováno v:
Cell Transplantation, Vol 24 (2015)
Acute hepatic failure (AHF) is a severe liver injury leading to sustained damage and complications. Induced pluripotent stem cells (iPSCs) may be an alternative option for the treatment of AHF. In this study, we reprogrammed human dental pulp-derived
Externí odkaz:
https://doaj.org/article/152e9c67a9114235af0db9143345e213