Výsledky vyhledávání - "Chiako, Farshadfar"

Blockage of the Monoamine Oxidase by a Natural Compound to Overcome Parkinson’s Disease via Computational Biology

Autor: Mahsa Sherafatizangeneh, Chiako Farshadfar, Nooshin Mojahed, Akbar Noorbakhsh, Noeman Ardalan

Publikováno v: Journal of Computational Biophysics and Chemistry. 21:373-387

The dopamine (DA) metabolism changes are significant in Parkinson’s disease (PD). Levels of monoamine oxidases (MAOs) play a critical role in DA metabolism and oxidative damage. Increased levels of the MAO-B enzyme in the elderly raise oxidative da

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::09350b07318cbbb4890cb7b9bf16f0c8
https://doi.org/10.1142/s2737416522500156

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Structural screening into the recognition of a potent inhibitor against non-structural protein 16: a molecular simulation to inhibit SARS-CoV-2 infection

Autor: Barzan Amjadi, Noeman Ardalan, Seyed Hamid Seyedi, Mohammad Shakib Alhagh, Mehran Ahmadizad, Chiako Farshadfar, Elnaz Hosseininezhadian Koushki

Publikováno v: Journal of Biomolecular Structure and Dynamics. 40:14115-14130

COVID-19 infection is caused by endemic crown infection (SARS-CoV-2) and is associated with lung damage and severe immune response. Non-Structural Proteins are the central components of coronaviral transcription and replication machinery in SARS-CoV-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24d5a0e4d1195d086fd4d8c168bd7cd0
https://doi.org/10.1080/07391102.2021.2001374

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Prevention of SARS-CoV-2 Proliferation with a Novel and Potent Main Protease Inhibitor by Docking, ADMET, MM-PBSA, and Molecular Dynamics Simulation

Autor: Mohammad Shakib Alhagh, Noeman Ardalan, Arian Rahimi, Seyed Hamid Seyedi, Mehran Ahmadizad, Rafee Habib Askandar, Elnaz Hosseininezhadian Koushki, Chiako Farshadfar, Akbar Noorbakhsh

Publikováno v: Journal of Computational Biophysics and Chemistry. 20:305-322

COVID-19 is the last disease caused by SARS-CoV-2 associated with a severe immune response and lung damage. The main protease (Mpro) has a vital role in SARS-CoV-2 proliferation. Moreover, humans lack homologous Mpro, which makes the Mpro a suitable

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4774b357ace95e1a6fc1c80b06b790aa
https://doi.org/10.1142/s2737416521500149

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Designing a natural inhibitor against human kynurenine aminotransferase type II and a comparison with PF-04859989: a computational effort against schizophrenia

Autor: Noeman Ardalan, Chiako Farshadfar, Elnaz Hosseininezhadian Koushki, Akbar Noorbakhsh

Publikováno v: Journal of Biomolecular Structure and Dynamics. 40:7038-7051

The Kynurenine aminotransferase II (KATII) enzyme has an essential role in L-kynurenine transmission to kynurenic acid (KYNA). High concentration of kynurenic acid associates with schizophrenia and some neurocognitive disorders. Decreasing KYNA produ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00ac6c10c0aca8ce0d56669598efd8cb
https://doi.org/10.1080/07391102.2021.1893817

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The SARS-Cov-2 Proliferation Blocked by a Novel and Potent Main Protease Inhibitor via Computer-aided Drug Design

Autor: Sepideh, Shayan, Shahab, Jamaran, Rafee Habib, Askandar, Arian, Rahimi, Azam, Elahi, Chiako, Farshadfar, Noeman, Ardalan

Publikováno v: Iranian Journal of Pharmaceutical Research : IJPR

The recent prevalence of novel “coronavirus disease 2019” has expanded quickly globally, causing a universal pandemic. Herein, an effort was constructed to design a potent drug to inhibit the main protease of SARS-Cov-2 (3CLp) by means of structu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9c456a531cda1f5460af4d047edc2f57
https://pubmed.ncbi.nlm.nih.gov/34903997

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Structure-based virtual screening, molecular docking and dynamics studies of natural product and classical inhibitors against human dihydrofolate reductase

Autor: Fatemeh Abdi, Chiako Farshadfar, Seyedeh Sara Moosavi, Sako Mirzaie, Bayazid Hasanpour, Elnaz Hosseininezhadian Koushki, Solmaz Abolghasemi, Mojtaba Aghaeepoor, Adriano Mollica, Babisandz Feyzi

Publikováno v: Network Modeling Analysis in Health Informatics and Bioinformatics. 9

Folate antagonists are classified as important and valuable therapeutic agents against infection, neoplastic, and inflammatory diseases. Dihydrofolate reductase (DHFR) is a biological target of two well-defined folate antagonists, classical and non-c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fcdc7ca9d4fc90c6138a1fc92247e88c
https://doi.org/10.1007/s13721-020-00244-9

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Identification of DNA gyrase Subunit a Mutations Associated with Ciprofloxacin Resistance in Staphylococcus aureus Isolated from Nasal Infection in Kurdistan-Iran

Autor: Chiako Farshadfar, Sheida Sadat Zonouri, Somayeh Tavana, Roya Darbani, Hamidreza Saljoughi

Publikováno v: Journal of Molecular Biology Research. 7:186

Fluoroquinolone antibiotics such as ciprofloxacin are useful drugs against infections caused by Staphylococcus aureus and mutations in DNA gyrase which control bacterial DNA topology, can be one of the reason of occurrence resistance to this class of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3d270db441a1fbda777c1f071dcbd575
https://doi.org/10.5539/jmbr.v7n1p186

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