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pro vyhledávání: '"Chiaki S. Kwok"'
Publikováno v:
The Journal of Heart and Lung Transplantation. 23:1003-1007
Stretch-activated ion channels (SACs) mediate abnormal ion currents in dilated cardiomyopathy (DCM), but their role in the contractile defect of DCM is undefined. We hypothesized that SAC antagonists would enhance contractile function in a hamster mo
Publikováno v:
The Journal of surgical research. 139(2)
Objectives The lanthanide cation, gadolinium (Gd 3+ ), accelerates recovery of stunned myocardium when given prior to ischemia. This study sought to determine whether giving Gd 3+ during ischemia or during reperfusion also ameliorates stunning, as th
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 280(3)
We tested the hypothesis that overstretching the myocardium could induce and/or exacerbate contractile dysfunction via stretch-activated (SA) ion channels. Maximum developed tension (Tmax), normalized to a control value, was compared in guinea pig pa