Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Chiaki Nagai"'
Autor:
Kazuhiro Abe, Mami Ozako, Miki Inukai, Yoe Matsuyuki, Shinnosuke Kitayama, Chisato Kanai, Chiaki Nagai, Chai C. Gopalasingam, Christoph Gerle, Hideki Shigematsu, Nariyoshi Umekubo, Satoshi Yokoshima, Atsushi Yoshimori
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-14 (2023)
Abstract Existing drugs often suffer in their effectiveness due to detrimental side effects, low binding affinity or pharmacokinetic problems. This may be overcome by the development of distinct compounds. Here, we exploit the rich structural basis o
Externí odkaz:
https://doaj.org/article/cece4c3a0c2549c0b39e71717c9e426c
Autor:
Yoko Itakura, Yasuko Hasegawa, Yurika Kikkawa, Yuina Murakami, Kosuke Sugiura, Chiaki Nagai-Okatani, Norihiko Sasaki, Mariko Umemura, Yuji Takahashi, Tohru Kimura, Atsushi Kuno, Toshiyuki Ishiwata, Masashi Toyoda
Publikováno v:
Regenerative Therapy, Vol 22, Iss , Pp 68-78 (2023)
Introduction: Heart failure is caused by various factors, making the underlying pathogenic mechanisms difficult to identify. Since cardiovascular disease tends to worsen over time, early diagnosis is key for treatment. In addition, understanding the
Externí odkaz:
https://doaj.org/article/b2bed5b042084a44a29c66a2c5018059
Autor:
Akihisa Kimura, Hiroyuki Takahama, Toshio Nishikimi, Seiji Takashio, Tomohiro Hayashi, Chiaki Nagai‐Okatani, Yasuaki Nakagawa, Satoshi Yasuda, Toshihisa Anzai, Naoto Minamino, Chisato Izumi
Publikováno v:
ESC Heart Failure, Vol 8, Iss 6, Pp 5617-5621 (2021)
Abstract Aims The methodology to distinguish between the heart failure (HF) with recovered ejection fraction (HFrecEF) and those with continuously reduced ejection fraction (EF) (HFcrEF) on admission has not been established. We recently demonstrated
Externí odkaz:
https://doaj.org/article/47cbc8c4efc040a4bcc930e944f1f9dd
Autor:
Takanori Wagatsuma, Chiaki Nagai-Okatani, Atsushi Matsuda, Yohei Masugi, Masako Imaoka, Ken Yamazaki, Michiie Sakamoto, Atsushi Kuno
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Aberrant protein glycosylation is one of the most notable features in cancerous tissues, and thereby glycoproteins with disease-relevant glycosylation alterations are fascinating targets for the development of biomarkers and therapeutic agents. For t
Externí odkaz:
https://doaj.org/article/ff9570c6fa9541608221d7a12cb4daba
Autor:
Hiroyuki Takahama, Toshio Nishikimi, Seiji Takashio, Tomohiro Hayashi, Chiaki Nagai‐Okatani, Takashi Asada, Akihiro Fujiwara, Yasuaki Nakagawa, Masashi Amano, Yasuhiro Hamatani, Atsushi Okada, Makoto Amaki, Takuya Hasegawa, Hideaki Kanzaki, Kunihiro Nishimura, Satoshi Yasuda, Kenji Kangawa, Toshihisa Anzai, Naoto Minamino, Chisato Izumi
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 17 (2019)
Background Early detection for worsening renal function (WRF) is indispensable in patients with acute decompensated heart failure (HF). We tested the hypothesis that the difference in the circulating levels of each B‐type or brain natriuretic pepti
Externí odkaz:
https://doaj.org/article/dc9bb77da4d84fa0ad8fe395581520ab
Autor:
Chiaki Nagai-Okatani, Kiyoko F Aoki-Kinoshita, Shuichi Kakuda, Misugi Nagai, Kozue Hagiwara, Katsue Kiyohara, Noriaki Fujita, Yoshinori Suzuki, Takashi Sato, Kiyohiko Angata, Atsushi Kuno
Publikováno v:
Molecules, Vol 24, Iss 16, p 2962 (2019)
For the effective discovery of the biological roles and disease-specific alterations concerning protein glycosylation in tissue samples, it is important to know beforehand the quantitative and qualitative variations of glycan structures expressed in
Externí odkaz:
https://doaj.org/article/3445adf5ed2741daa1e0a30b893f7646
Autor:
Chiaki Nagai-Okatani, Naoto Minamino
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0150210 (2016)
Targeted proteomics focusing on post-translational modifications, including glycosylation, is a useful strategy for discovering novel biomarkers. To apply this strategy effectively to cardiac hypertrophy and resultant heart failure, we aimed to chara
Externí odkaz:
https://doaj.org/article/166967e30aaa4e088bbdf5c59ffdc2c8
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0156501 (2016)
Recently, we identified an orphan Bombyx mori neuropeptide G protein-coupled receptor (BNGR)-A24 as an ion transport peptide-like (ITPL) receptor. BNGR-A24 belongs to the same clade as BNGR-A32 and -A33, which were recently identified as natalisin re
Externí odkaz:
https://doaj.org/article/3fa9f94ab5a847078f3f93775ec19e10
Autor:
Seyed Ali Ghoreishi-Madiseh, Toshiyuki Tosha, Chiaki Nagai, Sajjan Pokhrel, Agus P. Sasmito, Tatsuya Tanaka, Atsushi Sainoki
Publikováno v:
Renewable Energy. 182:521-535
The experimental and computational analyses of a 500 m deep coaxial borehole heat exchanger system for geothermal power generation are studied in this paper. The experiments are carried out on a high temperature resourced well with an average thermal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40616acc6dcddd87f54693e660bc98c6
https://doi.org/10.1016/j.renene.2021.10.038
https://doi.org/10.1016/j.renene.2021.10.038
Autor:
Toshihisa Anzai, Tomohiro Hayashi, Yasuaki Nakagawa, Chisato Izumi, Satoshi Yasuda, Akihisa Kimura, Seiji Takashio, Toshio Nishikimi, Hiroyuki Takahama, Naoto Minamino, Chiaki Nagai-Okatani
Publikováno v:
ESC Heart Failure
ESC Heart Failure, Vol 8, Iss 6, Pp 5617-5621 (2021)
ESC Heart Failure, Vol 8, Iss 6, Pp 5617-5621 (2021)
Aims The methodology to distinguish between the heart failure (HF) with recovered ejection fraction (HFrecEF) and those with continuously reduced ejection fraction (EF) (HFcrEF) on admission has not been established. We recently demonstrated that the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09818e0acb3a09e0b03721b4432f6306
http://europepmc.org/articles/PMC8712908
http://europepmc.org/articles/PMC8712908