Výsledky vyhledávání - "Chiaki Mitsumasu"

Akademický článek

Alterations of gene expression and glutamate clearance in astrocytes derived from an MeCP2-null mouse model of Rett syndrome.

Autor: Yasunori Okabe, Tomoyuki Takahashi, Chiaki Mitsumasu, Ken-ichiro Kosai, Eiichiro Tanaka, Toyojiro Matsuishi

Publikováno v: PLoS ONE, Vol 7, Iss 4, p e35354 (2012)

Rett syndrome (RTT) is a neurodevelopmetal disorder associated with mutations in the methyl-CpG-binding protein 2 (MeCP2) gene. MeCP2-deficient mice recapitulate the neurological degeneration observed in RTT patients. Recent studies indicated a role

Externí odkaz: https://doaj.org/article/eacd40d8bb4c4b9788e7186136b65aff

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Neural development of methyl-CpG-binding protein 2 null embryonic stem cells: A system for studying Rett syndrome

Autor: Tomoyuki Takahashi, Toyojiro Matsuishi, Ken-ichiro Kosai, Yasunori Okabe, Eiichiro Tanaka, Yoshinaka Murai, Akira Kusaga, Hideho Higashi, Chiaki Mitsumasu

Publikováno v: Brain Research. 1360:17-27

Mutations in methyl-CpG-binding protein 2 (MeCP2) gene cause the neurodevelopmental disorder Rett syndrome (RTT). Here, we describe a new experimental system that efficiently elucidates the role of MeCP2 in neural development. MeCP2-null and control

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb10202c90cd098a63ed62f13a2b56a4
https://doi.org/10.1016/j.brainres.2010.08.090

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Disturbance of cardiac gene expression and cardiomyocyte structure predisposes Mecp2-null mice to arrhythmias

Autor: Yasunori Okabe, Ken-ichiro Kosai, Genzou Takemura, Hideo Yasukawa, Kei-ichiro Nakamura, Tomoyuki Takahashi, Sachiyo Igata, Chiaki Mitsumasu, Yushiro Yamashita, Toyojiro Matsuishi, Tomoko Minami, Satoko Okayama, Munetsugu Hara, Makoto Takano, Eiichiro Tanaka

Publikováno v: Scientific Reports

Methyl-CpG-binding protein 2 (MeCP2) is an epigenetic regulator of gene expression that is essential for normal brain development. Mutations in MeCP2 lead to disrupted neuronal function and can cause Rett syndrome (RTT), a neurodevelopmental disorder

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c8e29573c4a4dcf0444b837b4480871
http://europepmc.org/articles/PMC4466896

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Alterations of gene expression and glutamate clearance in astrocytes derived from an MeCP2-null mouse model of Rett syndrome

Autor: Ken-ichiro Kosai, Tomoyuki Takahashi, Toyojiro Matsuishi, Yasunori Okabe, Eiichiro Tanaka, Chiaki Mitsumasu

Publikováno v: PLoS ONE, Vol 7, Iss 4, p e35354 (2012)
PLoS ONE

Rett syndrome (RTT) is a neurodevelopmetal disorder associated with mutations in the methyl-CpG–binding protein 2 (MeCP2) gene. MeCP2-deficient mice recapitulate the neurological degeneration observed in RTT patients. Recent studies indicated a rol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac1704184a78f21e809025b4461431bd
http://europepmc.org/articles/PMC3332111?pdf=render

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