Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Chia-wei Chou"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract CASTs use both CRISPR-associated proteins and Tn7-family transposons for RNA-guided vertical and horizontal transmission. CASTs encode minimal CRISPR arrays but can’t acquire new spacers. Here, we report that CASTs can co-opt defense-assoc
Externí odkaz:
https://doaj.org/article/87ad148d25754558b864c70a17ead820
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract CRISPR-Cas13d cleaves RNA and is used in vivo and for diagnostics. However, a systematic understanding of its RNA binding and cleavage specificity is lacking. Here, we describe an RNA Chip-Hybridized Association-Mapping Platform (RNA-CHAMP)
Externí odkaz:
https://doaj.org/article/707aad093e864c7e8d26b0eba435ea43
Autor:
Ching-Lin Hsieh, Scott A. Rush, Concepcion Palomo, Chia-Wei Chou, Whitney Pickens, Vicente Más, Jason S. McLellan
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
The degree to which the conformation of the human metapneumovirus fusion (F) protein affects immunogenicity has been debated. Here, Hsieh et al. engineer prefusion-stabilized F variants with enhanced thermostability that elicit higher neutralizing an
Externí odkaz:
https://doaj.org/article/1881314158b644b685989d8847d72882
Autor:
Ching-Lin Hsieh, Anne P. Werner, Sarah R. Leist, Laura J. Stevens, Ester Falconer, Jory A. Goldsmith, Chia-Wei Chou, Olubukola M. Abiona, Ande West, Kathryn Westendorf, Krithika Muthuraman, Ethan J. Fritch, Kenneth H. Dinnon, III, Alexandra Schäfer, Mark R. Denison, James D. Chappell, Ralph S. Baric, Barney S. Graham, Kizzmekia S. Corbett, Jason S. McLellan
Publikováno v:
Cell Reports, Vol 37, Iss 5, Pp 109929- (2021)
Summary: Current coronavirus (CoV) vaccines primarily target immunodominant epitopes in the S1 subunit, which are poorly conserved and susceptible to escape mutations, thus threatening vaccine efficacy. Here, we use structure-guided protein engineeri
Externí odkaz:
https://doaj.org/article/af2791637eea401ba71a9731ca3cb5c0
Autor:
Luo-Uei Liang, Yu-Hsiung Yen, Chia-Wei Chou, Ko-Hsuan Mandy Chen, Hsiao-Yu Lin, Sheng-Wen Huang, Minghwei Hong, Jueinai Kwo, Germar Hoffmann
Publikováno v:
AIP Advances, Vol 11, Iss 2, Pp 025245-025245-6 (2021)
The physical investigation of surfaces and their properties crucially depends on their quality. Such investigations are commonly performed in an ultra-high vacuum environment. Thereby, the transfer of samples among different setups and under ambient
Externí odkaz:
https://doaj.org/article/4c248d3dff3447839ac5e4bd4846e10f
Autor:
S. Wesley Long, Randall J. Olsen, Paul A. Christensen, David W. Bernard, James J. Davis, Maulik Shukla, Marcus Nguyen, Matthew Ojeda Saavedra, Prasanti Yerramilli, Layne Pruitt, Sishir Subedi, Hung-Che Kuo, Heather Hendrickson, Ghazaleh Eskandari, Hoang A. T. Nguyen, J. Hunter Long, Muthiah Kumaraswami, Jule Goike, Daniel Boutz, Jimmy Gollihar, Jason S. McLellan, Chia-Wei Chou, Kamyab Javanmardi, Ilya J. Finkelstein, James M. Musser
Publikováno v:
mBio, Vol 11, Iss 6 (2020)
ABSTRACT We sequenced the genomes of 5,085 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) strains causing two coronavirus disease 2019 (COVID-19) disease waves in metropolitan Houston, TX, an ethnically diverse region with 7 million res
Externí odkaz:
https://doaj.org/article/9f1850b41a7e45ea80ff416602d5d71c
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e18087 (2011)
Epidermal growth factor receptor (EGFR), a receptor tyrosine kinase which promotes cell proliferation and survival, is abnormally overexpressed in numerous tumors of epithelial origin, including colorectal cancer (CRC). EGFR monoclonal antibodies hav
Externí odkaz:
https://doaj.org/article/8b6202e4a8fe4e1e822398e9768553ef
Autor:
Chia-Wei Chou, 周嘉緯
104
This paper proposed a triangular current mode (TCM) control to implement three-phase interleaved boost converter for suppression the output low-frequency voltage ripple. This paper introduces the band-stop filter into the feedforward control
This paper proposed a triangular current mode (TCM) control to implement three-phase interleaved boost converter for suppression the output low-frequency voltage ripple. This paper introduces the band-stop filter into the feedforward control
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/82510715613384396040
Autor:
Chia-Wei Chou, 周家瑋
104
There are 206 bones and more than 70 joints in an adult’s body, which provides many degrees of freedom (DOFs) for humans to use. People’s motion in daily life can be simple or complex. However, how these large number of DOFs are utilized
There are 206 bones and more than 70 joints in an adult’s body, which provides many degrees of freedom (DOFs) for humans to use. People’s motion in daily life can be simple or complex. However, how these large number of DOFs are utilized
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/24228258531544116787
Autor:
Chia-Wei Chou, 周家緯
104
Sulfonucleotide reductase (SNR) catalyzes the first committed step in sulfate reduction for the biosynthesis of cysteine and is essential for survival in the latent phase of bacterial infection. However, metazoans do not possess the sulfate
Sulfonucleotide reductase (SNR) catalyzes the first committed step in sulfate reduction for the biosynthesis of cysteine and is essential for survival in the latent phase of bacterial infection. However, metazoans do not possess the sulfate
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/30013853219078829279