Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Chia-Yu Guh"'
Autor:
Chia-Yu Guh, Hong-Jhih Shen, Liv WeiChien Chen, Pei-Chen Chiu, I-Hsin Liao, Chen-Chia Lo, Yunfei Chen, Yu-Hung Hsieh, Ting-Chia Chang, Chien-Ping Yen, Yi-Yun Chen, Tom Wei-Wu Chen, Liuh-Yow Chen, Ching-Shyi Wu, Jean-Marc Egly, Hsueh-Ping Catherine Chu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Here the authors show TERRA R-loops recruit the endonuclease XPF to telomeres, leading to DNA double-strand breaks to activate break-induced telomere synthesis at telomeres that utilize the alternative lengthening of telomeres (ALT) pathway to extend
Externí odkaz:
https://doaj.org/article/a1fb0e9f73254a64ac93c3ea84dcbcc8
Publikováno v:
Journal of Biomedical Science, Vol 27, Iss 1, Pp 1-14 (2020)
Abstract Protein and DNA have been considered as the major components of chromatin. But beyond that, an increasing number of studies show that RNA occupies a large amount of chromatin and acts as a regulator of nuclear architecture. A significant fra
Externí odkaz:
https://doaj.org/article/73e484f2e3d84a9f9e89b4736e9331db
Autor:
Jeannie T. Lee, Yunfei Chen, Robert Morris, Myriam Boukhali, Anand Minajigi, Chia-Yu Guh, Wilhelm Haas, Hsueh-Ping Chu, Yu-Hung Hsieh
Publikováno v:
Nature Protocols. 16:3672-3694
More than 90% of the human genome is transcribed into noncoding RNAs, but their functional characterization has lagged behind. A major bottleneck in the understanding of their functions and mechanisms has been a dearth of systematic methods for ident
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b399099e33ce76f084491fb99303195
https://doi.org/10.1038/s41596-021-00555-9
https://doi.org/10.1038/s41596-021-00555-9
Autor:
Hsueh-Ping, Chu, Anand, Minajigi, Yunfei, Chen, Robert, Morris, Chia-Yu, Guh, Yu-Hung, Hsieh, Myriam, Boukhali, Wilhelm, Haas, Jeannie T, Lee
Publikováno v:
Nature protocols. 16(7)
More than 90% of the human genome is transcribed into noncoding RNAs, but their functional characterization has lagged behind. A major bottleneck in the understanding of their functions and mechanisms has been a dearth of systematic methods for ident
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::df1cfa5a2a5ba0d8e5c9ee47b3f4e7bb
https://pubmed.ncbi.nlm.nih.gov/34108731
https://pubmed.ncbi.nlm.nih.gov/34108731
Publikováno v:
Journal of Biomedical Science
Journal of Biomedical Science, Vol 27, Iss 1, Pp 1-14 (2020)
Journal of Biomedical Science, Vol 27, Iss 1, Pp 1-14 (2020)
Protein and DNA have been considered as the major components of chromatin. But beyond that, an increasing number of studies show that RNA occupies a large amount of chromatin and acts as a regulator of nuclear architecture. A significant fraction of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aeb8cd7fc682f062b74cba3b53f3539
http://europepmc.org/articles/PMC7079490
http://europepmc.org/articles/PMC7079490
Autor:
Stephanie Klosek, Nandakumar Mohan, Kian Parsa, Joyce Kong, Robert Lu, Chia-Yu Guh, Marti Goldenberg, Yun Chen, Beena Biju, Judy Huang, Hsueh-Ping Chu, Hilda A. Pickett, Xiaolei Pan, Naveed Ahmed, Dong Zhang
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Cancer cells maintain their telomeres by either re-activating telomerase or adopting the homologous recombination (HR)-based Alternative Lengthening of Telomere (ALT) pathway. Among the many prominent features of ALT cells, C-circles (CC) formation i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64abb7e42cc680fd630008fc6ca505cb
https://doi.org/10.1038/s41598-019-55537-5
https://doi.org/10.1038/s41598-019-55537-5