Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Chia-I Ko"'
Publikováno v:
Stem Cell Research, Vol 12, Iss 1, Pp 296-308 (2014)
The aryl hydrocarbon receptor (AHR) is a transcription factor and environmental sensor that regulates expression of genes involved in drug-metabolism and cell cycle regulation. Chromatin immunoprecipitation analyses, Ahr ablation in mice and studies
Externí odkaz:
https://doaj.org/article/158c4dd5366a425597031faee4c663bf
Autor:
Vinicius S Carreira, Yunxia Fan, Hisaka Kurita, Qin Wang, Chia-I Ko, Mindi Naticchioni, Min Jiang, Sheryl Koch, Xiang Zhang, Jacek Biesiada, Mario Medvedovic, Ying Xia, Jack Rubinstein, Alvaro Puga
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142440 (2015)
The Developmental Origins of Health and Disease (DOHaD) Theory proposes that the environment encountered during fetal life and infancy permanently shapes tissue physiology and homeostasis such that damage resulting from maternal stress, poor nutritio
Externí odkaz:
https://doaj.org/article/1c5042e38864471a8506ad8abb49a07f
Publikováno v:
Cell Biology and Toxicology.
Key regulatory decisions during cleavage divisions in mammalian embryogenesis determine the fate of preimplantation embryonic cells. Single-cell RNA sequencing of early-stage—2-cell, 4-cell, and 8-cell—blastomeres show that the aryl hydrocarbon r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5da223a67f3093c2b6ad4c9ae7dfb36
https://doi.org/10.1007/s10565-022-09755-9
https://doi.org/10.1007/s10565-022-09755-9
Publikováno v:
Toxicol Sci
The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor well-known for its adaptive role as a sensor of environmental toxicants and mediator of the metabolic detoxification of xenobiotic ligands. In addition, a growing body of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::453365756bce35c8fbbbd2f802395c56
https://pubmed.ncbi.nlm.nih.gov/34009372
https://pubmed.ncbi.nlm.nih.gov/34009372
Autor:
Matthew de Gannes, Xiang Zhang, Alvaro Puga, Mario Medvedovic, Chia-I Ko, Jack Rubinstein, Liang Niu, Jacek Biesiada, Sheryl E. Koch
Publikováno v:
Toxicol Sci
Congenital heart disease (CHD), the leading birth defect worldwide, has a largely unknown etiology, likely to result from complex interactions between genetic and environmental factors during heart development, at a time when the heart adapts to dive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e45f9183031c734271903668cd46ac3
https://europepmc.org/articles/PMC7706406/
https://europepmc.org/articles/PMC7706406/
Publikováno v:
Stem Cells. 34:2825-2839
Lack of cell cycle checkpoints and uninterrupted passage through S-phase continuously renew the embryonic stem (ES) cell population and maintain pluripotency. Here, we show that to regulate mitotic progression and pluripotency ES cells must keep the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4ede1e5ad9f8cf324d4d56860b1ab45
https://doi.org/10.1002/stem.2456
https://doi.org/10.1002/stem.2456
Autor:
Qing Wang, Mario Medvedovic, Yunxia Fan, Sheryl E. Koch, Mindi Naticchioni, Chia-I Ko, Min Jiang, Ying Xia, Jack Rubinstein, Xiang Zhang, Vinicius Carreira, Hisaka Kurita, Alvaro Puga
Publikováno v:
Toxicological Sciences. 147:425-435
Congenital heart disease (CHD) is the most common congenital abnormality and one of the leading causes of newborn death throughout the world. Despite much emerging scientific information, the precise etiology of this disease remains elusive. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::767d320b5c816c842e57fbe84fcb2fd1
https://doi.org/10.1093/toxsci/kfv138
https://doi.org/10.1093/toxsci/kfv138
Autor:
Alexandra Rizos, K. Ray Chaudhuri, Han-I Lin, Chia-Wen Chang, Chin-Hsien Lin, Jun-Yu Fan, Chia-I. Ko, Yih-Ru Wu
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Pain is a distressing symptom of Parkinson disease (PD). We aim to determine whether the genetic variants of chronic pain-related genes contribute to pain in PD patients. We included 418 PD patients and evaluated pain severity on King’s PD pain sca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61de63fb30c69260941535a0ae3a0453
https://doi.org/10.1038/s41598-017-06782-z
https://doi.org/10.1038/s41598-017-06782-z
Autor:
Alvaro Puga, Chia-I Ko
Recent evidence from embryonic stem cells suggests that the aryl hydrocarbon receptor (AHR) plays a central role in the regulation of pluripotency, a short-lived property of cells in the early blastula inner cell mass (ICM). Four key observations sup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26f5fe03ad626345e06697f83d796dd5
https://europepmc.org/articles/PMC5597055/
https://europepmc.org/articles/PMC5597055/
Publikováno v:
Stem Cell Research, Vol 12, Iss 1, Pp 296-308 (2014)
The aryl hydrocarbon receptor (AHR) is a transcription factor and environmental sensor that regulates expression of genes involved in drug-metabolism and cell cycle regulation. Chromatin immunoprecipitation analyses, Ahr ablation in mice and studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49b2cf29d4d36cb19408c259a4c1e0c2
https://doi.org/10.1016/j.scr.2013.11.007
https://doi.org/10.1016/j.scr.2013.11.007