Zobrazeno 1 - 10 of 39 pro vyhledávání: '"Chia Nung Hung"'
1
Akademický článek
Phagocytosis-initiated tumor hybrid cells acquire a c-Myc-mediated quasi-polarization state for immunoevasion and distant dissemination
Autor: Chih-Wei Chou, Chia-Nung Hung, Cheryl Hsiang-Ling Chiu, Xi Tan, Meizhen Chen, Chien-Chin Chen, Moawiz Saeed, Che-Wei Hsu, Michael A. Liss, Chiou-Miin Wang, Zhao Lai, Nathaniel Alvarez, Pawel A. Osmulski, Maria E. Gaczynska, Li-Ling Lin, Veronica Ortega, Nameer B. Kirma, Kexin Xu, Zhijie Liu, Addanki P. Kumar, Josephine A. Taverna, Gopalrao V. N. Velagaleti, Chun-Liang Chen, Zhao Zhang, Tim Hui-Ming Huang
Publikováno v: Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract While macrophage phagocytosis is an immune defense mechanism against invading cellular organisms, cancer cells expressing the CD47 ligand send forward signals to repel this engulfment. Here we report that the reverse signaling using CD47 as
Externí odkaz: https://doaj.org/article/2948fd02380348cca98fb04b6c8cbabb
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3
Akademický článek
AXL-initiated paracrine activation of pSTAT3 enhances mesenchymal and vasculogenic supportive features of tumor-associated macrophages
Autor: Chia-Nung Hung, Meizhen Chen, Daniel T. DeArmond, Cheryl H.-L. Chiu, Catherine A. Limboy, Xi Tan, Meena Kusi, Chih-Wei Chou, Li-Ling Lin, Zhao Zhang, Chiou-Miin Wang, Chun-Liang Chen, Kohzoh Mitsuya, Pawel A. Osmulski, Maria E. Gaczynska, Nameer B. Kirma, Ratna K. Vadlamudi, Don L. Gibbons, Steve Warner, Andrew J. Brenner, Daruka Mahadevan, Joel E. Michalek, Tim H.-M. Huang, Josephine A. Taverna
Publikováno v: Cell Reports, Vol 42, Iss 9, Pp 113067- (2023)
Summary: Tumor-associated macrophages (TAMs) are integral to the development of complex tumor microenvironments (TMEs) and can execute disparate cellular programs in response to extracellular cues. However, upstream signaling processes underpinning t
Externí odkaz: https://doaj.org/article/81e2c4bf9d664349a0f9840fc517001b
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4
Akademický článek
ERα-related chromothripsis enhances concordant gene transcription on chromosome 17q11.1-q24.1 in luminal breast cancer
Autor: Chun-Lin Lin, Xi Tan, Meizhen Chen, Meena Kusi, Chia-Nung Hung, Chih-Wei Chou, Ya-Ting Hsu, Chiou-Miin Wang, Nameer Kirma, Chun-Liang Chen, Ching-Hung Lin, Kate I. Lathrop, Richard Elledge, Virginia G. Kaklamani, Kohzoh Mitsuya, Tim H.-M. Huang
Publikováno v: BMC Medical Genomics, Vol 13, Iss 1, Pp 1-18 (2020)
Abstract Background Chromothripsis is an event of genomic instability leading to complex chromosomal alterations in cancer. Frequent long-range chromatin interactions between transcription factors (TFs) and targets may promote extensive translocation
Externí odkaz: https://doaj.org/article/91f5a5e5bf7c4250aa876d533ff61028
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10
Akademický článek
Characterization of sensory neuronal subtypes innervating mouse tongue.
Autor: Ping Wu, Dominic Arris, Max Grayson, Chia-Nung Hung, Shivani Ruparel
Publikováno v: PLoS ONE, Vol 13, Iss 11, p e0207069 (2018)
The tongue is uniquely exposed to water-soluble environmental chemicals that may lead to injury or tumorigenesis. However, comparatively little research has focused on the molecular and functional organization of trigeminal ganglia (TG) afferent neur
Externí odkaz: https://doaj.org/article/8e55bae867e540dca62d2467a0953cdb
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