Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Chia Liang Tai"'
Publikováno v:
ISSCC
The temperature sensing of a chip becomes more critical with the increment of the process and circuit complexity. In advanced processes, the heating effect becomes more severe due to the thermal accumulation within the small chip dimension. In order
Autor:
Hua-Hao Chiu, Jen-Shin Song, Wan-Ping Hsieh, Ming-Shiu Hung, Cheng-Ming Chu, Kak-Shan Shia, Yen-Shih Tung, Chun-Ping Chang, Yu-Sheng Chao, Shi-Liang Tseng, Chien-Huang Wu, Yinchiu Lin, Wan-Ling Chung, Chia-Liang Tai, Chun-Wei Kuo
Publikováno v:
Journal of Medicinal Chemistry. 51:5397-5412
Replacing the conventional pyrazole 5-aryl substituent of 1 (SR141716A) with the 2-thienyl moiety appended with an appropriate alkynyl unit, a novel class of 5-(5-alkynyl-2-thienyl)pyrazole derivatives, behaving as highly potent CB1 receptor antagoni
Autor:
Chao Yu-Sheng, Min-Tsang Hsieh, Chia Chien Hsieh, Kak Shan Shia, Chun Wei Kuo, Hui Chuan Wu, Wan Ping Hsieh, Chia Liang Tai, Ming Shiu Hung, Jing Po Tsao, Jen Shin Song, Shi Liang Tseng, Vijay D. Pawar, Hua Hao Chiu
Publikováno v:
Org. Biomol. Chem.. 6:447-450
A novel class of (5-(pent-1-enyl)thiophen-2-yl)pyrazole antagonists was discovered, many of which exhibited potent CB1 activity and good CB1/2 selectivity, suggesting that along with a 1,3-transposition of the carbonyl of the pyrazole 3-carboxamide,
Publikováno v:
A-SSCC
A digital LDO regulator provides a wide operating range and high efficiency. Accuracy is improved by using ripple reduction, output level dependent control, and auto-calibration. Fabricated in a 16nm FinFET CMOS process, the regulator accepts an inpu
Publikováno v:
ESSCIRC
Autor:
Shin-Ru Shih, Chia-Liang Tai, Chung-Chi Lee, Ying-Ting Lin, Chih-Shiang Chang, Yen-Chun Lee, Jyh-Haur Chern, Sung-Nien Tseng
Publikováno v:
Journal of Medicinal Chemistry. 48:3522-3535
A series of pyridylimidazolidinone derivatives was synthesized and tested in vitro against enterovirus 71 (EV71). On the basis of compound 33 (DBPR103), introduction of a methyl group at the 2- or 3-position of the linker between the imidazolidinone
Autor:
Chia-Liang Tai, Chih-Shiang Chang, Jyh-Haur Chern, Chung-Chi Lee, Ying-Ting Lin, Yen-Chun Lee, Ching-Yin Lee, Shin-Ru Shih, Kak-Shan Shia
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 14:5051-5056
A series of novel, oxime ether-containing pyridyl imidazolidinones were synthesized and their antiviral activity was evaluated in a plaque reduction assay. It is very interesting that this class of compounds is specific for human enteroviruses, in pa
Autor:
Jyh-Haur Chern, Chih-Shiang Chang, Chia-Liang Tai, Chungming Chang, Chung-Chi Lee, Huan-Yi Tseng, Ying-Ting Lin, Yen-Chun Lee, Kak-Shan Shia
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 14:1169-1172
A series of 5-substituted 2-cyanoimino-4-imidazodinone and 2-cyanoimino-4-pyrimidinone derivatives were synthesized and their anticancer cytotoxicity were evaluated in in vitro assay. It was found that the bulky aryl functionality in the 5-position o
Autor:
Tai Wei Ly, Jiunn-Cheh Guo, Hsing-Jang Liu, Nai-Wen Tseng, Jen-Dar Wu, Chia-Liang Tai, Kak-Shan Shia, Jinn-Kwei Liang
Publikováno v:
Tetrahedron. 59:1209-1226
4-Cyano-2-cyclohexenones were found to be susceptible to reductive alkylation reactions, giving the corresponding 2,2-disubstituted-3-cyclohexenone derivatives in a completely regioselective manner. This newly developed methodology has been successfu
Autor:
Max K. Leong, Huan-Yi Tseng, Kuan-Chang Peng, Yen-Chun Lee, Sung-Nien Tseng, Ming-Chu Hsu, Chia-Liang Tai, Shin-Ru Shih, Jyh-Haur Chern, Chung-Chi Lee, Wen-Tai Li, Shu-Jen Chen, Kak-Shan Shia, Chungming Chang, Yi-Ling Chang
Publikováno v:
Journal of Medicinal Chemistry. 45:1644-1655
When skeletons of Win compounds were used as templates, computer-assisted drug design led to the identification of a novel series of imidazolidinone derivatives with significant antiviral activity against enterovirus 71 (EV 71), the infection of whic