Zobrazeno 1 - 10
of 162
pro vyhledávání: '"Chia Lang Hsu"'
Autor:
Huai-Cheng Huang, Yen-Lin Huang, Yi-Ju Chen, Hsin-Yi Wu, Chia-Lang Hsu, Hsiang-Fong Kao, Bin-Chi Liao, Min-Shu Hsieh, Neng-Yu Lin, Yu-Hao Liao, Hsin-Lin Chen, Chun-Nan Chen, Tseng-Cheng Chen, Cheng-Ping Wang, Tsung-Lin Yang, Min-Chuan Huang, Mei-Chun Lin, Pei-Jen Lou
Publikováno v:
Oncogenesis, Vol 13, Iss 1, Pp 1-10 (2024)
Abstract Immunotherapy has revolutionized cancer treatment, but the lack of a reliable predictive biomarker for treatment response remains a challenge. Alpha-1,6-Mannosylglycoprotein 6-β-N-Acetylglucosaminyltransferase 5 (MGAT5) is a key regulator o
Externí odkaz:
https://doaj.org/article/70de69921c8547aeb318aa0db5ded965
Autor:
Kuei-Pin Chung, Chih-Ning Cheng, Yi-Jung Chen, Chia-Lang Hsu, Yen-Lin Huang, Min-Shu Hsieh, Han-Chun Kuo, Ya-Ting Lin, Yi-Hsiu Juan, Kiichi Nakahira, Yen-Fu Chen, Wei-Lun Liu, Sheng-Yuan Ruan, Jung-Yien Chien, Maria Plataki, Suzanne M. Cloonan, Peter Carmeliet, Augustine M. K. Choi, Ching-Hua Kuo, Chong-Jen Yu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-23 (2024)
Abstract Type 2 alveolar epithelial (AT2) cells of the lung are fundamental in regulating alveolar inflammation in response to injury. Impaired mitochondrial long-chain fatty acid β-oxidation (mtLCFAO) in AT2 cells is assumed to aggravate alveolar i
Externí odkaz:
https://doaj.org/article/5afa0e7fd12540ceb61a70ad3c0d6415
Autor:
Chien‐Chin Lin, Chi‐Yuan Yao, Yu‐Hung Wang, Yueh‐Chwen Hsu, Chang‐Tsu Yuan, Tsung‐Chih Chen, Chia‐Lang Hsu, Sze‐Hwei Lee, Jhih‐Yi Lee, Pin‐Tsen Shih, Chein‐Jun Kao, Po‐Han Chuang, Yuan‐Yeh Kuo, Hsin‐An Hou, Wen‐Chien Chou, Hwei‐Fang Tien
Publikováno v:
eJHaem, Vol 5, Iss 4, Pp 738-748 (2024)
Abstract Introduction IDH2 mutation is an unfavorable prognostic factor in patients with primary myelofibrosis (PMF) but its effect on myelofibrosis (MF) remains largely unclear. Methods In this study, we aimed to elucidate the roles of IDH2 mutation
Externí odkaz:
https://doaj.org/article/fa92d941b488439f9510b04086ba0152
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Background A rising population faces challenges with healing-impaired cutaneous wounds, often leading to physical disabilities. Adipose-derived stem cells (ASCs), specifically in the cell sheet format, have emerged as a promising remedy for
Externí odkaz:
https://doaj.org/article/bd0e09fe25314744a9eabe9b6af3e248
Autor:
Mei‐Chun Lin, Ya‐Ting Chuang, Hsin‐Yi Wu, Chia‐Lang Hsu, Neng‐Yu Lin, Min‐Chuan Huang, Pei‐Jen Lou
Publikováno v:
Molecular Oncology, Vol 18, Iss 2, Pp 350-368 (2024)
Cells in the tumor microenvironment (TME) communicate via membrane‐bound and secreted proteins, which are mostly glycosylated. Altered glycomes of malignant tumors influence behaviors of stromal cells. In this study, we showed that the loss of core
Externí odkaz:
https://doaj.org/article/e9ed1e8e7af94aa582632080fc33d22f
Publikováno v:
Journal of Microbiology, Immunology and Infection, Vol 57, Iss 1, Pp 64-75 (2024)
Background: B cells are essential for providing humoral protection against acute influenza A virus (IAV) infection. FcγRIIB, a regulator of antibody (Ab) production, influences immune responses during pathogen infections, but its specific impact on
Externí odkaz:
https://doaj.org/article/04486bd0b66b486ca3282ab2775994d9
Autor:
Shang-Gin Wu, Tzu-Hua Chang, Meng-Feng Tsai, Yi-Nan Liu, Yen-Lin Huang, Chia-Lang Hsu, Han-Nian Jheng, Jin-Yuan Shih
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 1, Pp 102091- (2024)
Osimertinib is an effective treatment option for patients with advanced non-small cell lung cancer (NSCLC) with EGFR activation or T790M resistance mutations; however, acquired resistance to osimertinib can still develop. This study explored novel mi
Externí odkaz:
https://doaj.org/article/0fe9a2a3fca74c738931950645a3cfe1
Autor:
Yi-Ling Chen, Yi-Nan Liu, Yen-Ting Lin, Meng-Feng Tsai, Shang-Gin Wu, Tzu-Hua Chang, Chia-Lang Hsu, Huey-Dong Wu, Jin-Yuan Shih
Publikováno v:
Journal of Biomedical Science, Vol 30, Iss 1, Pp 1-20 (2023)
Abstract Background Metastasis is a multistep process involving the migration and invasion of cancer cells and is a hallmark of cancer malignancy. Long non-coding RNAs (lncRNAs) play critical roles in the regulation of metastasis. This study aims to
Externí odkaz:
https://doaj.org/article/67e69c5d45e84907929dff4d4ef66aef
Autor:
Chun-Wei Li, Tai-Horng Young, Mu-Hui Wang, Ming-Ying Pei, Tsung-Yu Hsieh, Chia-Lang Hsu, Nai-Chen Cheng
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Background Application of autologous adipose-derived stem cells (ASC) for diabetic chronic wounds has become an emerging treatment option. However, ASCs from diabetic individuals showed impaired cell function and suboptimal wound healing eff
Externí odkaz:
https://doaj.org/article/55ff127c9c47438a8286fa0eb3aabc5e
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 14, p 7948 (2024)
Polycystic ovary syndrome (PCOS) is a female endocrine disorder with metabolic issues. Hyperandrogenism combined with hyperinsulinemia exacerbates the reproductive, metabolic, and inflammatory problems in PCOS patients. The etiology of PCOS is unclea
Externí odkaz:
https://doaj.org/article/7ecacfa0f021409694ab6dce5e745c0e