Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Chia Kuang Yen"'
Publikováno v:
Life, Vol 11, Iss 12, p 1371 (2021)
Colorectal cancer (CRC) is a highly lethal malignant cancer. Capecitabine, a 5-fluororacil (5-FU) derivate, is its first-line drug, but the resistance of CRC to capecitabine is still the most challenging factor for curing patients. It has been sugges
Externí odkaz:
https://doaj.org/article/ea556df585864fb1a48f8b7509143932
Autor:
Shun-Fu Chang, Cheng-Nan Chen, Jung-Chung Lin, Hsin-Ell Wang, Shigetarou Mori, Jia-Je Li, Chia-Kuang Yen, Ching-Yun Hsu, Chang-Phone Fung, Pele Choi-Sing Chong, Chih-Hsiang Leng, Yi-Jun Ding, Feng-Yee Chang, L. Kristopher Siu
Publikováno v:
Cells, Vol 9, Iss 5, p 1183 (2020)
Microbial proteins have recently been found to have more benefits in clinical disease treatment because of their better-developed strategy and properties than traditional medicine. In this study, we investigated the effectiveness of a truncated pepti
Externí odkaz:
https://doaj.org/article/6806e1d247c14f9aad73301aabdac450
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e113752 (2014)
Macrophage accumulation in the arterial wall and smooth muscle cell (SMC) proliferation are features of type 2 diabetes mellitus (DM) and its vascular complications. However, the effects of diabetic monocyte-derived macrophages on vascular SMC prolif
Externí odkaz:
https://doaj.org/article/73283034537b495cb6fd4ea39058901d
Autor:
Shun-Fu, Chang, Cheng-Nan, Chen, Jung-Chung, Lin, Hsin-Ell, Wang, Shigetarou, Mori, Jia-Je, Li, Chia-Kuang, Yen, Ching-Yun, Hsu, Chang-Phone, Fung, Pele Choi-Sing, Chong, Chih-Hsiang, Leng, Yi-Jun, Ding, Feng-Yee, Chang, L Kristopher, Siu
Publikováno v:
Cells
Microbial proteins have recently been found to have more benefits in clinical disease treatment because of their better-developed strategy and properties than traditional medicine. In this study, we investigated the effectiveness of a truncated pepti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6c5097896cef74fbb8c5b746e78905d1
https://pubmed.ncbi.nlm.nih.gov/32397494
https://pubmed.ncbi.nlm.nih.gov/32397494
Autor:
Jiunn-Ming Sheen, Te-Chuan Chen, Shao-Ju Chien, Mao-Lin Sung, Wen-Shih Huang, Tseng-Hsi Lin, Cheng-Nan Chen, Hsing-Chun Kuo, Chia-Kuang Yen
Publikováno v:
Journal of Biological Chemistry. 286:25564-25573
E-selectin expression by endothelial cells (ECs) is crucial for leukocyte recruitment during the inflammatory response. Macrophage accumulation and serum E-selectin elevation are features of type 2 diabetes mellitus. However, the interactions between
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb8e681a585396d4aa996bd0f4f7e781
https://doi.org/10.1074/jbc.m111.230540
https://doi.org/10.1074/jbc.m111.230540
Autor:
Yen Jen Chen, Ruei Ren Wu, Miao Ying Chang, Tzeng Horng Leu, Ching Jau Yang, Yung Kuo Li, Zuei Ching Chen, Ming Chei Maa, Ming Yu Hsieh, Chia Kuang Yen
Publikováno v:
The Journal of Nutritional Biochemistry. 21:1186-1192
Macrophage motility is vital in innate immunity. Lipopolysaccharide (LPS)-mediated macrophage migration requires the enhancement of Src expression and enzymatic activity, which can be regulated by inducible nitric oxide synthase (iNOS). As a major sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e94d4a8d1b6caddde61e1b38f04bf219
https://doi.org/10.1016/j.jnutbio.2009.10.004
https://doi.org/10.1016/j.jnutbio.2009.10.004
Autor:
Cheng-Nan Chen, Hsin-I Chang, Shu Chien, Ju-Chien Cheng, Mao Lin Sung, Chia Kuang Yen, Heng Jung Chen, Chia Ching Wu
Publikováno v:
Circulation Research. 105:755-763
Rationale : Hyperhomocysteinemia contributes to vascular dysfunction and risks of cardiovascular diseases. Stromal cell–derived factor (SDF)-1, a chemokine expressed by endothelial cells (ECs), is highly expressed in advanced atherosclerotic lesion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2288126af95d33276596f3126feb889
https://doi.org/10.1161/circresaha.109.206524
https://doi.org/10.1161/circresaha.109.206524
Publikováno v:
Molecular Immunology. 43:308-316
As tyrosine kinases are indispensable in lipopolysaccharide (LPS)-induced macrophage activation, the myeloid-specific Src members (i.e. Lyn, Fgr and Hck) are speculated to play important roles in this process. However, the normal LPS responsiveness i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a119db28ee8db2eae6507b355450be5e
https://doi.org/10.1016/j.molimm.2005.03.015
https://doi.org/10.1016/j.molimm.2005.03.015
Autor:
Mao-Lin Sung, Hsin-I Chang, Tzung-Chieh Tsai, Hong-Ren Yu, Jui-Kun Chiang, Hsing-Chun Kuo, Cheng-Nan Chen, Chia-Kuang Yen
Publikováno v:
Journal of cellular physiology. 226(4)
The mechanism of homocysteine-induced cell proliferation in human vascular smooth muscle cells (SMCs) remains unclear. We investigated the molecular mechanisms by which homocysteine affects the expression of cyclins A and D1 in human umbilical artery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::381d4fe0438e7ea57f51a27ce6592a04
https://pubmed.ncbi.nlm.nih.gov/20857402
https://pubmed.ncbi.nlm.nih.gov/20857402
Autor:
Ying Tai Jin, Hsiu Shan Yu, Yen Jen Chen, Ming Chei Maa, Jenq Chang Lee, Shan Tair Wang, Jung Hui Wang, Yuan Liu, Tzeng Horng Leu, Chia Kuang Yen
Publikováno v:
Molecular carcinogenesis. 43(4)
Epidemiological studies indicate that dietary fiber-derived fermentation products such as butyrate can prevent colon cancer development. To further dissect the role of butyrate in anticarcinogenesis, its effect on cellular growth and invasion as well
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8808872ec74f6eeff864fef66fb37bd8
https://pubmed.ncbi.nlm.nih.gov/16001424
https://pubmed.ncbi.nlm.nih.gov/16001424