Oncogenic activation of the STAT3 pathway drives PD-L1 expression in natural killer/T-cell lymphoma.

Autor: Song TL; Lymphoma Genomic Translational Research Laboratory, Division of Medical Oncology, and., Nairismägi ML; Lymphoma Genomic Translational Research Laboratory, Division of Medical Oncology, and., Laurensia Y; Lymphoma Genomic Translational Research Laboratory, Division of Medical Oncology, and., Lim JQ; Lymphoma Genomic Translational Research Laboratory, Division of Medical Oncology, and., Tan J; Lymphoma Genomic Translational Research Laboratory, Division of Medical Oncology, and.; Laboratory of Cancer Epigenome, Division of Medical Sciences, National Cancer Centre Singapore, Singapore.; State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, China., Li ZM; Laboratory of Cancer Epigenome, Division of Medical Sciences, National Cancer Centre Singapore, Singapore., Pang WL; Lymphoma Genomic Translational Research Laboratory, Division of Medical Oncology, and., Kizhakeyil A; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore., Wijaya GC; Laboratory of Cancer Epigenome, Division of Medical Sciences, National Cancer Centre Singapore, Singapore., Huang DC; Lymphoma Genomic Translational Research Laboratory, Division of Medical Oncology, and.; Laboratory of Cancer Epigenome, Division of Medical Sciences, National Cancer Centre Singapore, Singapore., Nagarajan S; Laboratory of Cancer Epigenome, Division of Medical Sciences, National Cancer Centre Singapore, Singapore., Chia BK; Lymphoma Genomic Translational Research Laboratory, Division of Medical Oncology, and., Cheah D; Lymphoma Genomic Translational Research Laboratory, Division of Medical Oncology, and., Liu YH; Department of Pathology, Guangdong General Hospital, Guangdong Academy of Medical Science, Guangzhou, China., Zhang F; Department of Pathology, Guangdong General Hospital, Guangdong Academy of Medical Science, Guangzhou, China., Rao HL; State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, China.; Department of Pathology, Sun Yat-Sen University Cancer Center, Guangzhou, China., Tang T; Division of Medical Oncology, National Cancer Centre Singapore, Singapore., Wong EK; Lymphoma Genomic Translational Research Laboratory, Division of Medical Oncology, and., Bei JX; State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, China., Iqbal J; Department of Anatomical Pathology, Division of Pathology, Singapore General Hospital, Singapore.; Duke-NUS Graduate Medical School, Singapore., Grigoropoulos NF; Department of Haematology, Singapore General Hospital, Singapore., Ng SB; Department of Pathology, Yong Loo Lin School of Medicine, and.; Department of Pathology, National University Hospital, Singapore.; National University Cancer Institute of Singapore, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore., Chng WJ; National University Cancer Institute of Singapore, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore., Teh BT; Laboratory of Cancer Epigenome, Division of Medical Sciences, National Cancer Centre Singapore, Singapore.; Division of Cancer and Stem Cell Biology, Duke-NUS Graduate Medical School, Singapore., Tan SY; Department of Pathology, Yong Loo Lin School of Medicine, and.; Department of Pathology, National University Hospital, Singapore.; Institute of Cell and Molecular Biology and., Verma NK; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore., Fan H; Bioinformatics Institute, A*STAR, Singapore.; Department of Biological Sciences, National University of Singapore, Singapore.; Centre for Computational Biology, DUKE-NUS Graduate Medical School, Singapore., Lim ST; Lymphoma Genomic Translational Research Laboratory, Division of Medical Oncology, and.; Division of Medical Oncology, National Cancer Centre Singapore, Singapore.; Office of Education, Duke-NUS Graduate Medical School, Singapore; and., Ong CK; Lymphoma Genomic Translational Research Laboratory, Division of Medical Oncology, and.; Genome Institute of Singapore, A*STAR, Singapore.

Publikováno v: Blood [Blood] 2018 Sep 13; Vol. 132 (11), pp. 1146-1158. Date of Electronic Publication: 2018 Jul 27.

OPERA-LG: efficient and exact scaffolding of large, repeat-rich eukaryotic genomes with performance guarantees.

Autor: Gao S; Computational and Systems Biology, Genome Institute of Singapore, Singapore, 138672, Singapore.; NUS Graduate School for Integrative Sciences and Engineering, Singapore, 117456, Singapore.; South Australian Health & Medical Research Institute, North Terrace, Adelaide, 5000, SA, Australia., Bertrand D; Computational and Systems Biology, Genome Institute of Singapore, Singapore, 138672, Singapore., Chia BK; Computational and Systems Biology, Genome Institute of Singapore, Singapore, 138672, Singapore., Nagarajan N; Computational and Systems Biology, Genome Institute of Singapore, Singapore, 138672, Singapore. nagarajann@gis.a-star.edu.sg.

Publikováno v: Genome biology [Genome Biol] 2016 May 11; Vol. 17, pp. 102. Date of Electronic Publication: 2016 May 11.

Systematic review on the efficacy, safety, and cost-effectiveness of topical calcineurin inhibitors in atopic dermatitis.

Autor: Chia BK; From the National Skin Centre, Singapore., Tey HL

Publikováno v: Dermatitis : contact, atopic, occupational, drug [Dermatitis] 2015 May-Jun; Vol. 26 (3), pp. 122-32.

The importance of study design for detecting differentially abundant features in high-throughput experiments.

Autor: Luo H, Li J, Chia BK, Robson P, Nagarajan N

Publikováno v: Genome biology [Genome Biol] 2014 Dec 03; Vol. 15 (12), pp. 527. Date of Electronic Publication: 2014 Dec 03.

Differential co-expression framework to quantify goodness of biclusters and compare biclustering algorithms.

Autor: Chia BK; Computational & Systems Biology, Genome Institute of Singapore, A-STAR, 60 Biopolis ST, Singapore. karuturikm@gis.a-star.edu.sg., Karuturi RK

Publikováno v: Algorithms for molecular biology : AMB [Algorithms Mol Biol] 2010 May 28; Vol. 5, pp. 23. Date of Electronic Publication: 2010 May 28.