Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Chia‐Lung Wu"'
Autor:
H. Mark Kenney, Javier Rangel-Moreno, Yue Peng, Kiana L. Chen, Jennifer Bruno, Abdul Embong, Elizabeth Pritchett, Jeffrey I. Fox, Enrique Becerril-Villanueva, Armando Gamboa-Domínguez, Sally Quataert, Gowrishankar Muthukrishnan, Ronald W. Wood, Benjamin D. Korman, Jennifer H. Anolik, Lianping Xing, Christopher T. Ritchlin, Edward M. Schwarz, Chia-Lung Wu
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionDefective lymphatic drainage and translocation of B-cells in inflamed (Bin) joint-draining lymph node sinuses are pathogenic phenomena in patients with severe rheumatoid arthritis (RA). However, the molecular mechanisms underlying this ly
Externí odkaz:
https://doaj.org/article/60bcac2b046f4b6fa2b4cb7c08b2c6e3
Autor:
H. Mark Kenney, Chia-Lung Wu, Alayna E. Loiselle, Lianping Xing, Christopher T. Ritchlin, Edward M. Schwarz
Publikováno v:
Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-20 (2022)
Abstract Background Lymphatic dysfunction exists in tumor necrosis factor transgenic (TNF-Tg) mice and rheumatoid arthritis (RA) patients. While joint-draining TNF-Tg popliteal lymphatic vessels (PLVs) have deficits in contractility during end-stage
Externí odkaz:
https://doaj.org/article/4e1ae8c2a72c4427a3e1df0e23045f60
Autor:
Amanda R Dicks, Grigory I Maksaev, Zainab Harissa, Alireza Savadipour, Ruhang Tang, Nancy Steward, Wolfgang Liedtke, Colin G Nichols, Chia-Lung Wu, Farshid Guilak
Publikováno v:
eLife, Vol 12 (2023)
Mutations in the TRPV4 ion channel can lead to a range of skeletal dysplasias. However, the mechanisms by which TRPV4 mutations lead to distinct disease severity remain unknown. Here, we use CRISPR-Cas9-edited human-induced pluripotent stem cells (hi
Externí odkaz:
https://doaj.org/article/4223b454adbc4d21a9b6aaa05a607eef
Autor:
Chia-Lung Wu, Amanda Dicks, Nancy Steward, Ruhang Tang, Dakota B. Katz, Yun-Rak Choi, Farshid Guilak
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Application of human induced pluripotent stem cells (hiPSCs) for tissue regeneration is hindered by off-target cell differentiation. Here, the authors use bulk and single cell RNA-sequencing to identify WNT and MITF as off-target hubs during chondrog
Externí odkaz:
https://doaj.org/article/4749da5248df4c6c9aa0688e0fb689a9
Autor:
Kelly A. Kimmerling, Sara J. Oswald, Janet L. Huebner, Dianne Little, Virginia B. Kraus, Jing X. Kang, Chia-Lung Wu, Farshid Guilak
Publikováno v:
Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-10 (2020)
Abstract Background Dietary fatty acid (FA) content has been shown to influence the development of post-traumatic osteoarthritis (PTOA) in obesity. We used the fat-1 transgenic mouse to examine the hypothesis that endogenous reduction of ω-6 to ω-3
Externí odkaz:
https://doaj.org/article/37d54ee769984a20a71f14b945b7f49b
Autor:
Amanda Dicks, Chia-Lung Wu, Nancy Steward, Shaunak S. Adkar, Charles A. Gersbach, Farshid Guilak
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-14 (2020)
Abstract Background Articular cartilage shows little or no capacity for intrinsic repair, generating a critical need of regenerative therapies for joint injuries and diseases such as osteoarthritis. Human-induced pluripotent stem cells (hiPSCs) offer
Externí odkaz:
https://doaj.org/article/f36c5cf155da46bd94d57c44b06c5220
Autor:
Ruhang Tang, Liufang Jing, Vincent P. Willard, Chia-lung Wu, Farshid Guilak, Jun Chen, Lori A. Setton
Publikováno v:
Stem Cell Research & Therapy, Vol 9, Iss 1, Pp 1-12 (2018)
Abstract Background Intervertebral disc (IVD) degeneration is characterized by an early decrease in cellularity of the nucleus pulposus (NP) region, and associated extracellular matrix changes, reduced hydration, and progressive degeneration. Cell-ba
Externí odkaz:
https://doaj.org/article/11b5e4d701e74f959d7918880ac5509a
Autor:
Brian O. Diekman, Chia-Lung Wu, Craig R. Louer, Bridgette D. Furman, Janet L. Huebner, Virginia B. Kraus, Steven A. Olson, Farshid Guilak
Publikováno v:
Cell Transplantation, Vol 22 (2013)
Joint injury dramatically enhances the onset of osteoarthritis (OA) and is responsible for an estimated 12% of OA. Posttraumatic arthritis (PTA) is especially common after intra-articular fracture, and no disease-modifying therapies are currently ava
Externí odkaz:
https://doaj.org/article/8b5afa67372e4ef1bfd364b830e8ca53
Autor:
Chia-Lung Wu, 吳佳龍
103
In recent years, the government is dedicated to the development of cloud information and aerospace industry. Cloud computing and UAV unmanned aerial vehicle (UAV) application are the development focus for the two industries. Cloud computing
In recent years, the government is dedicated to the development of cloud information and aerospace industry. Cloud computing and UAV unmanned aerial vehicle (UAV) application are the development focus for the two industries. Cloud computing
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/25769308616239600474
Autor:
Chia-Lung Wu, 吳嘉隆
103
In recent years, applying Visual Reference Station real-time dynamic positioning technology for control surveying does bring great convenience, and surveyor who can almost be " What You See Is What You Get" like instant access to high-precis
In recent years, applying Visual Reference Station real-time dynamic positioning technology for control surveying does bring great convenience, and surveyor who can almost be " What You See Is What You Get" like instant access to high-precis
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/71323672078790693516