Zobrazeno 1 - 10
of 231
pro vyhledávání: '"Chia‐Lin Chen"'
Publikováno v:
Urban Planning, Vol 8, Iss 3, Pp 69-83 (2023)
The need to prioritise the development of bus transport has attracted widespread attention in the literature. This study aims to investigate how buses can be used to facilitate a sustainable transport system, using Heze, in China, as a case study. Ou
Externí odkaz:
https://doaj.org/article/2fe1dda6548b49cf967ff2a346d5c230
Autor:
Chia‐Lin Chen, Juan Carlos Hernandez, Dinesh Babu Uthaya Kumar, Tatsuya Machida, Stanley M. Tahara, Anthony El‐Khoueiry, Meng Li, Vasu Punj, Suresh Kumar Swaminathan, Ameya Kirtane, Yibu Chen, Jayanth Panyam, Keigo Machida
Publikováno v:
Advanced Science, Vol 10, Iss 14, Pp n/a-n/a (2023)
Abstract A critical barrier to effective cancer therapy is the improvement of drug selectivity, toxicity, and reduced recurrence of tumors expanded from tumor‐initiating stem‐like cells (TICs). The aim is to identify circulating tumor cell (CTC)
Externí odkaz:
https://doaj.org/article/999c7bce83734a00a201565cd6d18f4d
Autor:
Yu‐Sheng Tseng, Yun‐Han Su, Chia‐Lin Chen, Ji Zhang, Chih‐Kuang Wang, Dorian Amir Henry Hanaor, Wen‐Fan Chen
Publikováno v:
Advanced Materials Interfaces, Vol 10, Iss 12, Pp n/a-n/a (2023)
Abstract A novel glass‐ceramic strategy for synthesizing mixed phase diopside (CaMgSi2O6)–lithium oxide (Li2O) bioceramics with excellent mechanical strength, superior biodegradation resistance, low environmental pH impact, enhanced bioactivity,
Externí odkaz:
https://doaj.org/article/0e1dc1d6675e486f815a44d7c3b9d2c2
Autor:
Juan Carlos Hernandez, Chia-Lin Chen, Tatsuya Machida, Dinesh Babu Uthaya Kumar, Stanley M. Tahara, Jared Montana, Linda Sher, Jake Liang, Jae U. Jung, Hidekazu Tsukamoto, Keigo Machida
Publikováno v:
iScience, Vol 26, Iss 3, Pp 106254- (2023)
Summary: Chemoresistance and plasticity of tumor-initiating stem-like cells (TICs) promote tumor recurrence and metastasis. The gut-originating endotoxin-TLR4-NANOG oncogenic axis is responsible for the genesis of TICs. This study investigated mechan
Externí odkaz:
https://doaj.org/article/226e0646bccf467da2d2c0e828ad246d
Autor:
Olivier Sykes, Chia-Lin Chen
Publikováno v:
Transactions of the Association of European Schools of Planning, Vol 6, Iss 1 (2022)
The causes and impacts of new and enduring regional inequalities have been much debated in many regions and countries around the globe over the past decade. This has been reflected in public and political discourse with references to and imaginaries
Externí odkaz:
https://doaj.org/article/e32225c64ef8476296832138d84f02dd
Autor:
Chia-Lin Chen, Sheng-Chieh Hsu, Tan-Ya Chung, Cheng-Ying Chu, Hung-Jung Wang, Pei-Wen Hsiao, Shauh-Der Yeh, David K. Ann, Yun Yen, Hsing-Jien Kung
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Alterations in metabolism and amino acid usage are common in cancer cells. Here, the authors show in prostate cancer cells that arginine globally upregulates nuclear-encoded oxidative phosphorylation genes by altering histone acetylation and retainin
Externí odkaz:
https://doaj.org/article/d64749011def4c1eae0aaa79e53f01e3
Autor:
Raphael Serna, Ambika Ramrakhiani, Juan Carlos Hernandez, Chia-Lin Chen, Chad Nakagawa, Tatsuya Machida, Ratna B. Ray, Xiaohang Zhan, Stanley M. Tahara, Keigo Machida
Publikováno v:
iScience, Vol 25, Iss 6, Pp 104325- (2022)
Summary: Metabolic syndrome is associated with obesity, insulin resistance, and the risk of cancer. We tested whether oncogenic transcription factor c-JUN metabolically reprogrammed cells to induce obesity and cancer by reduction of glucose uptake, w
Externí odkaz:
https://doaj.org/article/20cf7cd3e2b8421cb2b038cd1b6cc348
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
TEAD4 (TEA Domain Transcription Factor 4) is well recognized as the DNA-anchor protein of YAP transcription complex, which is modulated by Hippo, a highly conserved pathway in Metazoa that controls organ size through regulating cell proliferation and
Externí odkaz:
https://doaj.org/article/21eadfce02d44faba347ce9052984e6d
Autor:
Hye Yeon Choi, Hifzur R. Siddique, Mengmei Zheng, Yi Kou, Da-Wei Yeh, Tatsuya Machida, Chia-Lin Chen, Dinesh Babu Uthaya Kumar, Vasu Punj, Peleg Winer, Alejandro Pita, Linda Sher, Stanley M. Tahara, Ratna B. Ray, Chengyu Liang, Lin Chen, Hidekazu Tsukamoto, Keigo Machida
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Normal stem cells are maintained by asymmetric cell division, but this process is dysregulated in tumour initiating stem-like cells (TICs). Here, the authors show that TBC1D15 impairs the asymmetric division machinery and activates NOTCH pathway for
Externí odkaz:
https://doaj.org/article/b860fba9de8448de8c15f0811ec7cae9
Autor:
Yi-An Ko, Yueh-Hsiang Yu, Yen-Fei Wu, Yung-Chieh Tseng, Chia-Lin Chen, King-Siang Goh, Hsin-Yu Liao, Ting-Hua Chen, Ting-Jen Rachel Cheng, An-Suei Yang, Chi-Huey Wong, Che Ma, Kuo-I Lin
Publikováno v:
PLoS Pathogens, Vol 17, Iss 8 (2021)
Hemagglutinin (HA) is the immunodominant protein of the influenza virus. We previously showed that mice injected with a monoglycosylated influenza A HA (HAmg) produced cross-strain-reactive antibodies and were better protected than mice injected with
Externí odkaz:
https://doaj.org/article/74ae43827c054dd89beda4ed1ea0e547