Zobrazeno 1 - 10
of 310
pro vyhledávání: '"Chia, I. P."'
Autor:
Chao-Yu Yang, Yi-Chun Tseng, Yi-Fan Tu, Bai-Jiun Kuo, Li-Chung Hsu, Chia-I Lien, You-Sheng Lin, Yin-Ting Wang, Yen-Chen Lu, Tsung-Wei Su, Yu-Chih Lo, Su-Chang Lin
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract cFLIP, a master anti-apoptotic regulator, targets the FADD-induced DED complexes of procaspase-8 in death receptor and ripoptosome signaling pathways. Several tumor cells maintain relatively high levels of cFLIP in achieving their immortalit
Externí odkaz:
https://doaj.org/article/b5842367d1a0401d8ba54c4ee9b33b37
Autor:
Huan-Yun Wu, Chi-Sheng Wang, Yuan-Chen Liu, Ching-Chun Chung, Wan-Ling Chen, Chia-I Tsai, Chiann-Yi Hsu, Chi-Hsiang Chou
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Laser acupuncture is a proven non-invasive treatment with effects comparable to traditional acupuncture in different types of headaches, but there is still insufficient evidence for chronic migraine (CM) in adults. We aim to inves
Externí odkaz:
https://doaj.org/article/30bb47df7b5b49dd9c05084c0a9e5caf
Publikováno v:
Advanced Science, Vol 11, Iss 41, Pp n/a-n/a (2024)
Abstract Proteins with intrinsically disordered regions (IDRs) often undergo phase separation to control their functions spatiotemporally. Changing the pH alters the protonation levels of charged sidechains, which in turn affects the attractive or re
Externí odkaz:
https://doaj.org/article/4a14fefd0ad24ba6b684a449db70ba2c
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 16 (2024)
Background: Programmed cell death protein 1 ligand 1 (PD-L1) expression alone may not be the optimal predictor of immunotherapy (IO) efficacy in advanced non-small cell lung cancer (NSCLC). Evaluation of circulating immune signatures using mass cytom
Externí odkaz:
https://doaj.org/article/8791fb4a97c24b9189c6b513f7aceb20
Autor:
Chao-Yu Yang, Chia-I Lien, Yi-Chun Tseng, Yi-Fan Tu, Arkadiusz W. Kulczyk, Yen-Chen Lu, Yin-Ting Wang, Tsung-Wei Su, Li-Chung Hsu, Yu-Chih Lo, Su-Chang Lin
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Fas-associated protein with death domain (FADD), procaspase-8, and cellular FLICE-inhibitory proteins (cFLIP) assemble through death-effector domains (DEDs), directing death receptor signaling towards cell survival or apoptosis. Understandin
Externí odkaz:
https://doaj.org/article/9ebe13928bbd4e0f95f815de3b2c8bef
Autor:
Konstantin Penkov, Igor Bondarenko, Daria Viktorovna Saenko, Yaroslav Kulyaba, Jun Guo, Yi Gong, Noboru Yamamoto, Yevhen Stepanovych Hotko, Vasyl Boyko, Natalya Vladimirovna Fadeeva, Grygorii Mykolaiovych Ursol, Hee Kyung Ahn, Nikolay Viktorovich Kislov, Chia-I Shen, Craig Davis, Karey Kowalski, Elisabete Michelon, Dmitri Pavlov, Tomoko Hirohashi, Byoung Chul Cho
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 16 (2024)
Background: Sasanlimab (PF-06801591), a humanized immunoglobulin G4 monoclonal antibody, binds to programmed cell death protein-1 (PD-1), preventing ligand (PD-L1) interaction. Objectives: To evaluate pharmacokinetics (PK), safety, tolerability, and
Externí odkaz:
https://doaj.org/article/a3ad25bc9da747acad6405e92fd609c8
Publikováno v:
Foods, Vol 13, Iss 23, p 3750 (2024)
The excessive consumption of red meat, such as beef, is a growing global health concern linked to increased risks of cancer and cardiovascular diseases. The health consequences associated with red meat consumption were estimated to cost USD 285 billi
Externí odkaz:
https://doaj.org/article/3c8554f9196e4da4a183995a3d70896f
Autor:
Chao-Yu Yang, Yi-Chun Tseng, Yi-Fan Tu, Bai-Jiun Kuo, Li-Chung Hsu, Chia-I Lien, You-Sheng Lin, Yin-Ting Wang, Yen-Chen Lu, Tsung-Wei Su, Yu-Chih Lo, Su-Chang Lin
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/9d349485eb5a46b5a738415605fc051d
Autor:
Jiun-Chi Huang, Ya-Chin Huang, Chia-Hsin Lu, Yun-Shiuan Chuang, Hsu-Han Chien, Chia-I Lin, Ming-Fang Chao, Hung-Yi Chuang, Chi-Kung Ho, Chao-Ling Wang, Chia-Yen Dai
Publikováno v:
Life, Vol 14, Iss 11, p 1399 (2024)
Background: Metabolic Score for Visceral Fat (METS-VF) is a novel indicator for estimating intra-abdominal fat, yet its connection with coronary artery calcification (CAC) remains uncharted. Our research aims to explore the novel METS-VF indicator’
Externí odkaz:
https://doaj.org/article/598f11008e304663b709dd0567112ff4
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundPulmonary infections are a crucial health concern for patients with advanced non–small-cell lung cancer (NSCLC). Whether the clinical outcome of pulmonary infection is influenced by immunotherapy(IO) remains unclear. By evaluating immune
Externí odkaz:
https://doaj.org/article/e47016c1e7a845a4945899bdc26960c0