Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Chi-Tat Lam"'
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0177276 (2017)
PURPOSE:This study aims to establish a highly adaptable workflow downstream of microfluidic enrichment for facilitating systematic CTC enumeration and genetic discovery. METHODS:To facilitate CTC enumeration, we established a CK/EPCAM-combined immuno
Externí odkaz:
https://doaj.org/article/a72c4decaf834e30848de9cd937ee1f8
Supplementary Figures S1-S4; Supplementary Tables S1-S5.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e827e05076fc19ec8a6c2bdc4c33df4
https://doi.org/10.1158/1078-0432.22441372
https://doi.org/10.1158/1078-0432.22441372
Purpose: Brain-derived neurotrophic factor (BDNF) has emerged as a novel angiogenic factor, and yet its impact on tumorigenesis is unclear. This study aimed at investigating the roles of BDNF in angiogenesis and tumor development.Experimental Design:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::446a498f53479e7f6908be596cf550c6
https://doi.org/10.1158/1078-0432.c.6518458
https://doi.org/10.1158/1078-0432.c.6518458
Publikováno v:
Journal of Cancer
Purpose: This study aims to develop a liquid biopsy assay to identify HCC and differentially diagnose hepatocellular carcinoma (HCC) from colorectal carcinoma (CRC) liver metastasis. Methods: Thirty-two microRNAs ("HallMark-32" panel) were designed t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a3277dbb6194cf51900b47e99dfa316
https://pubmed.ncbi.nlm.nih.gov/34149922
https://pubmed.ncbi.nlm.nih.gov/34149922
Autor:
Jin-zhong Pang, Mei-Yu Hu, Jie Chen, Lun-xiu Qin, Jmc Luk, Zhi Xu, Yvonne C. F. Su, Felice Ho-Ching Tsang, Kang-da Liu, Chi-tat Lam, Sarwat Fatima
Publikováno v:
Protein & Peptide Letters. 16:479-485
A monoclonal antibody, McAb9E (IgG3), was generated against a metastatic HCC cell line, MHCC-1. The antigen was characterized as human Caveolin-1 (Cav-1, 21kDa), with pI of 5.65. The Cav-1 antigen was found significantly over expressed in metastatic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::038c18cf2f0e6e1305ea19b481e44abe
https://doi.org/10.2174/092986609788167743
https://doi.org/10.2174/092986609788167743
Publikováno v:
Cancer Letters. 273:201-209
The present study investigated the effect of mammalian target of rapamycin (mTOR) inhibition on HCC cells in vitro and in vivo, either alone or in combination with cytotoxic agents. In vitro, HCC cell lines were exposed to RAD001, an mTOR inhibitor,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f451370c9a17495d6f7527edb0b2939c
https://doi.org/10.1016/j.canlet.2008.08.018
https://doi.org/10.1016/j.canlet.2008.08.018
Publikováno v:
Biochemical and Biophysical Research Communications. 348:1443-1448
Inhibition of HIF-1alpha activity provides an important strategy for the treatment of cancer. Recently, 3-(5'-hydroxymethyl-2'-furyl)-1-benzyl indazole (YC-1) has been identified as an anti-HIF-1alpha drug in cancer therapy with unclear molecular mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e457721a5b1065afe4720aaf4724409
https://doi.org/10.1016/j.bbrc.2006.08.015
https://doi.org/10.1016/j.bbrc.2006.08.015
Autor:
Zhen Fan Yang, Sheung Tat Fan, David W. Ho, Ronnie T.P. Poon, Chi Keung Lau, Chi Tat Lam, KH Tam
Publikováno v:
Biochemical and Biophysical Research Communications. 346:981-985
Platelets are an important place for the storage of angiogenic factors, such as vascular endothelial growth factor (VEGF) and brain-derived neurotrophic factor (BDNF). The present study aims to investigate the interaction between BDNF-TrkB pathway an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::531c9473ae1956b82e2def42d04e5b86
https://doi.org/10.1016/j.bbrc.2006.06.007
https://doi.org/10.1016/j.bbrc.2006.06.007
Autor:
Chi Keung Lau, David W. Ho, Zhen Fan Yang, Sheung Tat Fan, Chi Tat Lam, Ronnie T.P. Poon, Ching Tung Lum
Publikováno v:
International Immunology. 17:1391-1397
Our previous studies revealed that macrophages played an important role in linking injury, inflammatory and immune response in small-for-size liver transplantation. However, the molecular basis that promoted macrophage activation was not clear. In th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c24fa1af176a0fc605f00c4c6d9e9928
https://doi.org/10.1093/intimm/dxh316
https://doi.org/10.1093/intimm/dxh316