Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Chi-Qi Chen"'
Publikováno v:
Journal of Cellular Biochemistry. 116:287-298
Honokiol, a constituent of Magnolia officinalis, has been reported to possess potent anti-cancer activity through targeting multiple signaling pathways in numerous malignancies including acute myeloid leukemia (AML). However, the underlying mechanism
Autor:
Jun Jie Chen, Cheng-shui Chen, Shenmeng Gao, Chi-qi Chen, Lian-ping Zhou, Jianbo Wu, Wei-wei Jin, Hong-lei Xu
Publikováno v:
Molecular and Cellular Biochemistry. 383:137-148
Histone deacetylases (HDACs) inhibitor is a promising new approach to the treatment of lung cancer therapy via inhibiting cell growth and inducing apoptosis. miR-15a and miR-16-1 are important tumor suppressors through modulating B cell lymphoma 2 (B
Autor:
Jianbo Wu, Shen-meng Gao, Chong-yun Xing, Shenghui Zhang, Chi-qi Chen, Junjun Yang, Haiying Li, Lei Jiang
Publikováno v:
Leukemia & Lymphoma. 52:2365-2371
miR-15a and miR-16-1 (miR-15a/16-1) have been implicated in apoptosis, cell cycle regulation and chemosensitivity of tumor cells, but little is known about the role of miR-15a/16-1 in the differentiation of leukemic cells. In this study, we found tha
Autor:
Fule Wang, Feiyan Lin, Yingxia Tan, Yixiang Han, Shen Meng Gao, Lei Jiang, Chi-qi Chen, Jianbo Wu
Publikováno v:
Cell Biology International. 35:891-896
TIEG1 (TGF-β inducible early gene 1) plays a significant role in regulating cell proliferation and apoptosis in various cell types. Previous studies have shown a close relationship between the expression level of TIEG1 and various cancers, including
Autor:
Shen-meng Gao, Jianbo Wu, Lihui Yin, Chi-qi Chen, Chong-yun Xing, Yanxia Tan, Aifang Ye, Lei Jiang, Kang Yu
Publikováno v:
Biochemical and Biophysical Research Communications. 403:203-208
MicroRNAs (miRNAs) are small noncoding RNAs that regulate target gene expression through translation repression or messenger RNA degradation. MiR-15a and 16-1 form a cluster at the chromosomal region 13q14, which is frequently deleted or down-regulat
Publikováno v:
Zhongguo shi yan xue ye xue za zhi. 22(5)
This study was aimed to detect the expression of Musashi-2 (Msi2) in acute myeloid leukemia (AML) and investigate the relationship between Msi2 and other clinical parameters, especially CD34. A total RNA was extracted from bone marrow of newly diagno
Publikováno v:
Journal of cellular biochemistry. 116(2)
Honokiol, a constituent of Magnolia officinalis, has been reported to possess potent anti-cancer activity through targeting multiple signaling pathways in numerous malignancies including acute myeloid leukemia (AML). However, the underlying mechanism
Autor:
Chi-qi Chen, Kang Yu, Qing-xian Yan, Yi Chen, Shen-meng Gao, Chong-yun Xing, Zhuang Yan, Yi-fen Shi, Ke-Wen Zhao
Publikováno v:
Carcinogenesis. 34(7)
Suppressors of cytokine signaling, SOCS1 and SOCS3, are important negative regulators of Janus kinase 2/signal transducers and activators of transcription signaling, which is constitutively activated in myeloproliferative neoplasms (MPNs) and leukemi
Autor:
Jianbo Wu, Jun Jun Yang, Lu Yao Wang, Kang Yu, Chi Qi Chen, Chong Yun Xing, Jun Jie Chen, Li Ping Ye, Shen Meng Gao
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 31, Iss 1, p 27 (2012)
Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research : CR
Background Pure curcumin has been reported to down-regulate the expression of WT1 in leukemic cells. However, the molecular mechanism underlying the down-regulation of WT1 by curcumin is not completely delineated. The purpose of this present study is
Publikováno v:
Experimental Hematology. 41:261-270.e4
Constitutive activation of Janus kinase 2/signal transducers and activators of transcription (JAK2/STAT) signaling has an important role in the oncogenesis of myeloproliferative neoplasms (MPNs) and leukemia. Histone deacetylases (HDACs) inhibitors h