Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Chi-Hung Siu"'
Publikováno v:
Biochemical Journal. 459:241-249
In Dictyostelium discoideum , TgrB1 and TgrC1 are partners of a heterophilic cell-adhesion system. To investigate its assembly process, the split GFP complementation assay was used to track the oligomeric status of both proteins. The ability of TgrC1
Publikováno v:
Biochemical Journal. 452:259-269
Cell–cell adhesion plays crucial roles in cell differentiation and morphogenesis during development of Dictyostelium discoideum . The heterophilic adhesion protein TgrC1 (Tgr is transmembrane, IPT, IG, E-set, repeat protein) is expressed during cel
Publikováno v:
Indian Journal of Microbiology. 53:460-466
In Dictyostelium, soluble cell adhesion molecule, DdCAD-1, regulates cell-cell interaction through an unknown anchoring protein on the plasma membrane. Far western blot analysis using different probes revealed that the potential DdCAD-1 interacting p
Publikováno v:
FEBS Journal. 280:1795-1806
The Ca2+-dependent cell–cell adhesion molecule DdCAD-1, encoded by the cadA gene of Dictyostelium discoideum, is synthesized at the onset of development as a soluble protein and then transported to the plasma membrane by contractile vacuoles. Calmo
Autor:
Alexander Thomson, Gong Chen, Shrivani Sriskanthadevan, Jun Wang, Chunxia Yang, Chi-Hung Siu, Liansheng Hou, Xiaoqun Xu
Publikováno v:
Development, Growth & Differentiation. 53:518-527
The social amoeba Dictyostelium discoideum is a simple but powerful model organism for the study of cell–cell adhesion molecules and their role in morphogenesis during development. Three adhesive systems have been characterized and studied in detai
Publikováno v:
Molecular Biology of the Cell. 17:1261-1272
N-cadherin is recruited to the heterotypic contact during transendothelial migration of melanoma cells in a coculture system with tumor cells seeded on top of a monolayer of endothelial cells. However, β-catenin dissociates from N-cadherin and redis
Publikováno v:
Molecular Biology of the Cell. 16:4386-4397
Cancer metastasis is a multistep process involving many types of cell-cell interactions, but little is known about the adhesive interactions and signaling events during extravasation of cancer cells. Transendothelial migration of cancer cells was inv
Autor:
Tony J. C. Harris, Chi-Hung Siu
Publikováno v:
BioEssays. 24:996-1003
Cell adhesion complexes are critical for the physical coordination of cell–cell interactions and the morphogenesis of tissues and organs. Many adhesion receptors are anchored to the plasma membrane by a glycosylphosphatidylinositol (GPI) moiety and
Autor:
Paul M. Yip, Chi-Hung Siu
Publikováno v:
Journal of Neurochemistry. 76:1552-1564
Treatment of PC12 cells with nerve growth factor induces their differentiation into sympathetic neuron-like cells and the concomitant expression of the neural cell adhesion molecule L1, a member of the Ig superfamily. To investigate the mechanism of
Publikováno v:
Journal of Biological Chemistry. 276:48764-48774
The phospholipid-anchored membrane glycoprotein (gp)-80 mediates cell-cell adhesion through a homophilic trans-interaction mechanism during Dictyostelium development and is enriched in a Triton X-100-insoluble floating fraction. To elucidate how gp80