Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Chi-Hui Tsai"'
Publikováno v:
Journal of Natural Products. 79:1719-1723
The new flavone-glycoside aciculatin (1), from Chrysopogon aciculatus, has been shown to have cytotoxic, anti-inflammatory, and antiarthritis activity. Further biological studies have been limited because of the limited availability of 1 from natural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00ab8f47dfce65f8c7782440c0f7e176
https://doi.org/10.1021/acs.jnatprod.5b01051
https://doi.org/10.1021/acs.jnatprod.5b01051
Publikováno v:
Organic Letters. 10:1927-1930
The direct coupling of a variety of amides with CH2 Cl2 or CD2 Cl2 promoted by TiCl 4/Mg/THF provides an extremely simple, practical, selective, and efficient approach for the construction of methyl ketones. The efficiency and practicability of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aea59ee963e739ff82789d70ddbfd7e
https://doi.org/10.1021/ol8004326
https://doi.org/10.1021/ol8004326
Autor:
Szu-Huei Wu, Teng-Kuang Yeh, Jinq-Chyi Lee, Chidambaram Ramesh Kumar, Yu-Wei Liu, Chun-Hsu Yao, Jen-Shin Song, Yu-Lin Huang, Tsung-Chih Hsieh, Min-Hsien Wang, Chi-Hui Tsai, Chiung-Tong Chen, Chung-Yu Huang
Publikováno v:
European journal of medicinal chemistry. 55
Sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors are the current focus on the indication for the management of hyperglycemia in diabetes. Here, a novel series of C-linked indolylxyloside-based inhibitors of SGLT2 has been discovered. Stru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83e9944e1593bccdf6152223a67e34fe
https://pubmed.ncbi.nlm.nih.gov/22818040
https://pubmed.ncbi.nlm.nih.gov/22818040
Publikováno v:
ChemInform. 42
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::063c7d026c43a4acd9b2d04e5760d316
https://doi.org/10.1002/chin.201149195
https://doi.org/10.1002/chin.201149195
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 17(31)
The first total synthesis of cytopiloyne 1, a novel bioactive polyacetylenic glucoside isolated from the extract of Bidens pilosa, is described. The structure of cytopiloyne was determined to be 2-β-D-glucopyranosyloxy-1-hydroxytrideca-5,7,9,11-tetr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64fdfd89cb96d2802db321aecebdc74d
https://pubmed.ncbi.nlm.nih.gov/21681841
https://pubmed.ncbi.nlm.nih.gov/21681841
Autor:
Ming-Shiu Hung, Chun-Hsu Yao, Ching-Hui Chiu, Kuang-Feng Chu, Jinq-Chyi Lee, Chiung-Tong Chen, Wen-Chi Hsiao, Chieh-Jui Hsieh, Chi-Hui Tsai, Min-Hsien Wang, Szu-Huei Wu, Jen-Shin Song, Chih-Chun Chang, Chung-Yu Huang, Tsung-Chih Hsieh, Teng-Kuang Yeh, Mao-Chia Yuan, Yu-Wei Liu, Yu-Sheng Chao
Publikováno v:
Journal of medicinal chemistry. 54(1)
A novel series of N-linked β-D-xylosides were synthesized and evaluated for inhibitory activity against sodium-dependent glucose cotransporter 2 (SGLT2) in a cell-based assay. Of these, the 4-chloro-3-(4-cyclopropylbenzyl)-1-(β-D-xylopyranosyl)-1H-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::498249353d9bfcc5ef610e29ef3bcdd4
https://pubmed.ncbi.nlm.nih.gov/21128592
https://pubmed.ncbi.nlm.nih.gov/21128592
Autor:
Chieh-Jui Hsieh, Yi-Hui Peng, Jen-Shin Song, Mohane Selvaraj Coumar, Jian-Sung Wu, Su-Ying Wu, Jiun-Ming Wu, Chi-Hui Tsai, Chiung-Tong Chen, Jinq-Chyi Lee, Szu-Huei Wu, Yu-Sheng Chao, Yu-Wei Liu
Publikováno v:
Journal of medicinal chemistry. 53(24)
A ligand-based virtual screening strategy (a combination of pharmacophore model generation, shape-based scoring, and structure clustering analysis) was developed to discover novel SGLT2 inhibitors. The best pharmacophore model, generated from eight g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fa5f4b6910b281a9a8fd96f5031b58b
https://pubmed.ncbi.nlm.nih.gov/21090651
https://pubmed.ncbi.nlm.nih.gov/21090651
Publikováno v:
ChemInform. 39
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::488227deef8992f9133d6c9e3eaf97a7
https://doi.org/10.1002/chin.200841082
https://doi.org/10.1002/chin.200841082
Autor:
Chia-Chung Tsai, Chi-Hui Tsai, Tu-Hsin Yan, Ching-Ting Chien, Ying-Chuan Wang, Ping-Kuei Tsai, Tsai-Yuan Chang
Publikováno v:
The Journal of organic chemistry. 71(11)
The Ti−Mg−dichloromethylene complexes derived from the oxidative addition of CCl4 to the Mg−TiCl4 bimetallic species serve as a novel class of ambiphilic dichlorocarbenoid equivalents. Not only is Ti−Mg−dichlorocarbenoid highly selective bu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c7eb6319f11717dac0574f58638e07e
https://pubmed.ncbi.nlm.nih.gov/16709081
https://pubmed.ncbi.nlm.nih.gov/16709081
Autor:
Liang-Rui Chen1,2 lrchen@cc.ncue.edu.tw, Chi-Hui Tsai3 chtsai@cc.hwh.edu.tw, Yuan-Li Lin2, Yen-Shin Lai3,4 yslai@ntut.edu.tw
Publikováno v:
IEEE Transactions on Energy Conversion. Jun2010, Vol. 25 Issue 2, p484-493. 10p.