Výsledky vyhledávání - "Chi-Deu Chang"

Comparison of the analytic sensitivities of a recombinant immunoblot assay and the radioimmune precipitation assay for the detection of antibodies to Trypanosoma cruzi in patients with Chagas disease

Autor: Benedict A. Marchlewicz, Dinesh O. Shah, Kevin Y. Cheng, Louis V. Kirchhoff, Chi-Deu Chang, Vince A. Salbilla, Neeraj Adya

Publikováno v: Diagnostic Microbiology and Infectious Disease. 67:402-405

The diagnosis of chronic Chagas disease usually is made by detecting antibodies to Trypanosoma cruzi, the protozoan parasite that causes this illness. A highly sensitive and specific immunoblot assay developed by us showed a higher analytic sensitivi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb3a2e51fe41af0cd32ca724111333af
https://doi.org/10.1016/j.diagmicrobio.2010.03.013

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SOLID PHASE SYNTHESIS WITHOUT REPETITIVE ACIDOLYSIS

Autor: Theodore Lambros, M Waki, Chi-Deu Chang, Raymond Makofske, Johannes Meienhofer, Edgar P. Heimer

Publikováno v: International Journal of Peptide and Protein Research. 13:35-42

The utility of repetitive nonhydrolytic base cleavage of alpha-amino protective groups in solid phase peptide synthesis is shown by a preparation of the model tetrapeptide leucyl-alanyl-glycyl-valine on a p-benzyloxybenzyl ester polystyrene--1% divin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::02e5b31572dd475b8f0064827063fee6
https://doi.org/10.1111/j.1399-3011.1979.tb01847.x

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SOLID-PHASE PEPTIDE SYNTHESIS USING MILD BASE CLEAVAGE OF NαFLUORENYLMETHYLOXYCARBONYLAMINO ACIDS, EXEMPLIFIED BY A SYNTHESIS OF DIHYDROSOMATOSTATIN

Autor: Johannes Meienhofer, Chi-Deu Chang

Publikováno v: International Journal of Peptide and Protein Research. 11:246-249

N alpha-9-Fluorenylmethyloxycarbonyl (Fmoc) amino acids will be of advantage in solid phase peptide synthesis. The Fmoc-group is quantitatively cleaved by mild base (piperidine). This permits the use of tert-butyl-type side chain blocking and of pept

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11dc16cc1762c5426493f5d0999eae0f
https://doi.org/10.1111/j.1399-3011.1978.tb02845.x

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STABLE ISOLATED SYMMETRICAL ANHYDRIDES OF Nα-9-FLUORENYLMETHYLOXYCARBONYLAMINO ACIDS IN SOLID-PHASE PEPTIDE SYNTHESIS

Autor: Edgar P. Heimer, Johannes Meienhofer, Chi-Deu Chang, Theodore Lambros

Publikováno v: International Journal of Peptide and Protein Research. 18:237-241

The synthesis and isolation of symmetrical anhydrides of N alpha-9-fluorenylmethyloxycarbonyl (Fmoc) amino acids using water soluble carbodiimide is described. These compounds were used in a solid phase peptide synthesis of methionine-enkephalin on a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c858598ba13dbf23676a0ed218df0ea4
https://doi.org/10.1111/j.1399-3011.1981.tb02977.x

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SOLID-PHASE PEPTIDE SYNTHESIS OF SOMATOSTATIN USING MILD BASE CLEAVAGE OF Nα-9- FLUORENYLMETHYLOXYCARBONYLAMINO ACIDS

Autor: Arthur Felix, Chi-Deu Chang, Johannes Meienhofer, Manuel H. Jimenez

Publikováno v: International Journal of Peptide and Protein Research. 15:485-494

Experimental details for the "Fmoc solid phase peptide synthesis" of somatostatin are described. The 9-fluorenylmethyloxycarbonyl group was rapidly and quantitatively cleaved by 55% piperidine in dimethylformamide and monitored (u.v.) manually. For a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbe7658f3483c661036ba3920753a5b9
https://doi.org/10.1111/j.1399-3011.1980.tb02926.x

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Immunoblot Assay Using Recombinant Antigens as a Supplemental Test To Confirm the Presence of Antibodies to Trypanosoma cruzi

Autor: Vince A. Salbilla, David A. Leiby, Louis V. Kirchhoff, Kevin Y. Cheng, Dinesh O. Shah, Gerald Schochetman, Chi-Deu Chang

Publikováno v: Clinical and Vaccine Immunology. 14:355-361

The diagnosis of chronic Chagas' disease is generally made by detecting antibodies to Trypanosoma cruzi . Most conventional serological tests are based on lysates of whole parasites or semipurified antigen fractions from T. cruzi epimastigotes grown

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aa8a45d15153dc75d49142633e4a798
https://doi.org/10.1128/cvi.00401-06

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Evaluation of a prototype Trypanosoma cruzi antibody assay with recombinant antigens on a fully automated chemiluminescence analyzer for blood donor screening

Autor: Kevin Y. Cheng, David A. Leiby, Dinesh O. Shah, Alla S. Haller, Vince A. Salbilla, Jane D. Bryant, Gerald Schochetman, Louis V. Kirchhoff, Chi-Deu Chang, Alex W. Yem, Lily Jiang

Publikováno v: Transfusion. 46:1737-1744

BACKGROUND: Chagas disease is caused by Trypanosoma cruzi, a protozoan parasite that can be transmitted by transfusion. The diagnosis of chronic T. cruzi infection is generally made by detecting specific antibodies that bind to parasite antigens. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a63d8df58d353638dad2a4f722f22235
https://doi.org/10.1111/j.1537-2995.2006.00965.x

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