Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Chi-Chung Wu"'
Autor:
Chi-Chung Wu, Arica Beisaw
Publikováno v:
Developmental dynamics : an official publication of the American Association of Anatomists.
Cardiovascular disease is a leading cause of death worldwide. Due to the limited proliferative and regenerative capacity of adult cardiomyocytes, the lost myocardium is not replenished efficiently and is replaced by a fibrotic scar, which eventually
Publikováno v:
Journal of Medical Sciences, Vol 35, Iss 1, Pp 22-27 (2015)
Purpose: Prednisolone (Kidsolone) is an anti-inflammatory drug that is mainly used for patients with chronic obstructive airway diseases (COAD), such as asthma and chronic obstructive pulmonary diseases (COPD). The objective of this study was to dete
Externí odkaz:
https://doaj.org/article/eebe563c0bee4c3f8939af507dc73851
Autor:
Linda Kessler, Rui Gao, Nalan Tetik-Elsherbiny, Olga Lityagina, Azhar Zhailauova, Yonggang Ren, Felix A. Trogisch, Julio Cordero, Yanliang Dou, Yinuo Wang, Evgeny Chichelnitskiy, Joscha Alexander Kraske, Patricia Laura Schäfer, Chi-Chung Wu, Guillermo Barreto, Michael Potente, Thomas Wieland, Roxana Ola, Joerg Heineke, Gergana Dobreva
SummaryDuring embryogenesis, distinct cardiac cell types form, which shape the structural and functional properties of the heart. How their activity is coordinated is largely unknown. Here we show that Rnf20 is a multifaceted regulator of cardiac mor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78bbdc7923cb36fe8a3a715995f874ca
https://doi.org/10.1101/2022.09.16.508288
https://doi.org/10.1101/2022.09.16.508288
Publikováno v:
Journal of Orthopaedic Surgery, Vol 25 (2017)
Purpose: Pipkin type IV femoral head (FH) fracture was thought as poor prognosis. There were several surgical approaches and treatments for this difficult fracture. However, there was no one treatment superior to another. We reviewed a serious of pat
Externí odkaz:
https://doaj.org/article/4643289706f84eb59501d66236645675
Autor:
Jeroen Bakkers, Teun P. de Boer, Mohankrishna Dalvoy Vasudevarao, Alberto Bertozzi, Medhanie A. Mulaw, Charlotte D. Koopman, Chi-Chung Wu, Phong D. Nguyen, Gilbert Weidinger
Publikováno v:
Developmental Biology. Academic Press
Adult zebrafish are frequently described to be able to "completely" regenerate the heart. Yet, the extent to which cardiomyocytes lost to injury are replaced is unknown, since existing evidence for cardiomyocyte proliferation is indirect or non-quant
Publikováno v:
Circulation Research. 127:896-907
Rationale: After birth, cycling mammalian CMs (cardiomyocytes) progressively lose the ability to undergo cytokinesis and hence they become binucleated, which leads to cell cycle exit and loss of regenerative capacity. During late embryonic and early
Autor:
Arica Beisaw, Julia Dallmann, Mario Looso, Stefan Guenther, Chi-Chung Wu, Mette Bentsen, Didier Y.R. Stainier, Carsten Kuenne
Publikováno v:
Circ Res
Rationale: The adult human heart is an organ with low regenerative potential. Heart failure following acute myocardial infarction is a leading cause of death due to the inability of cardiomyocytes to proliferate and replenish lost cardiac muscle. Whi
Publikováno v:
In Free Radical Biology and Medicine 1999 27 Supplement 1:S122-S122
Publikováno v:
Developmental biology. 481
Zebrafish can achieve scar-free healing of heart injuries, and robustly replace all cardiomyocytes lost to injury via dedifferentiation and proliferation of mature cardiomyocytes. Previous studies suggested that Wnt/β-catenin signaling is active in
Autor:
David C Zebrowski, Silvia Vergarajauregui, Chi-Chung Wu, Tanja Piatkowski, Robert Becker, Marina Leone, Sofia Hirth, Filomena Ricciardi, Nathalie Falk, Andreas Giessl, Steffen Just, Thomas Braun, Gilbert Weidinger, Felix B Engel
Publikováno v:
eLife, Vol 4 (2015)
Mammalian cardiomyocytes become post-mitotic shortly after birth. Understanding how this occurs is highly relevant to cardiac regenerative therapy. Yet, how cardiomyocytes achieve and maintain a post-mitotic state is unknown. Here, we show that cardi
Externí odkaz:
https://doaj.org/article/73a4b7d81d6f4b3db404f9f302d8a689