Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Chi-Bun Chan"'
Autor:
Brian Pak Shing Pang, Elsie Chit Yu Iu, Miaojia Hang, Wing Suen Chan, Margaret Chui Ling Tse, Connie Tsz Ying Yeung, Mingfu Wang, Parco Ming Fai Siu, Chi Wai Lee, Keqiang Ye, Ho So, Chi Bun Chan
Publikováno v:
Redox Biology, Vol 78, Iss , Pp 103418- (2024)
Idiopathic inflammatory myopathy (commonly known as myositis) is a group of immune-related diseases characterized by muscle damage, weakness, and fatigue with unknown causes. Although overactivated innate immunity is a widely believed cause of myosit
Externí odkaz:
https://doaj.org/article/b6aa2e0182fa4232ab5528cb781dfb07
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Sporadic inclusion body myositis (sIBM) is a distinct subcategory of Idiopathic Inflammatory Myopathies (IIM), characterized by unique pathological features such as muscle inflammation, rimmed vacuoles, and protein aggregation within the myofibers. A
Externí odkaz:
https://doaj.org/article/d204be5e6dee4eb98ac97704226a43ac
Autor:
Ruolin Yan, Vivian Wai Wan Choi, Tania Hartono, Iris Mei Ying Tse, Margaret Chui Ling Tse, Yunpeng Zhou, Jinfeng Xu, Wai Hung Sit, Jennifer Man Fan Wan, Edmund Tsz Shing Li, Chi Bun Chan, Jimmy Chun Yu Louie
Publikováno v:
Frontiers in Nutrition, Vol 9 (2022)
IntroductionControversies surround the issue if chronic consumption of a high-sugar diet is detrimental to health or not. This study investigates whether lifelong consumption of a higher sucrose diet will induce overeating, and obesity, and cause met
Externí odkaz:
https://doaj.org/article/1d3f021a890343e994edff81b727a720
Autor:
Wei-hua Jia, Nuo-qi Wang, Lin Yin, Xi Chen, Bi-yu Hou, Jin-hua Wang, Gui-fen Qiang, Chi Bun Chan, Xiu-ying Yang, Guan-hua Du
Publikováno v:
Biology of Sex Differences, Vol 11, Iss 1, Pp 1-13 (2020)
Abstract Fibroblast growth factors (FGFs) belong to a large family comprising 22 FGF polypeptides that are widely expressed in tissues. Most of the FGFs can be secreted and involved in the regulation of skeletal muscle function and structure. However
Externí odkaz:
https://doaj.org/article/0f22bd2693ef47f593565f477e2aed12
Autor:
Elsie Chit Yu Iu, Chi Bun Chan
Publikováno v:
Biology, Vol 11, Iss 7, p 1063 (2022)
Brain-derived neurotrophic factor (BDNF) is an important growth factor in the central nervous system. In addition to its well-known activities in promoting neuronal survival, neuron differentiation, and synaptic plasticity, neuronal BDNF also regulat
Externí odkaz:
https://doaj.org/article/f5f5dd77e5614f119cb0522678009132
Autor:
Zora Chui-Kuen Chan, Hiu-Lam Rachel Kwan, Yin Shun Wong, Zhixin Jiang, Zhongjun Zhou, Kin Wai Tam, Ying-Shing Chan, Chi Bun Chan, Chi Wai Lee
Publikováno v:
eLife, Vol 9 (2020)
At vertebrate neuromuscular junctions (NMJs), the synaptic basal lamina contains different extracellular matrix (ECM) proteins and synaptogenic factors that induce and maintain synaptic specializations. Here, we report that podosome-like structures (
Externí odkaz:
https://doaj.org/article/41831c1fbf05419382d5b06f6cc8b329
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
In mammals, local production of tumor necrosis factor α (TNFα) inhibits growth hormone (GH)-induced IGF-I expression at tissue level and contributes to GH resistance caused by sepsis/endotoxemia and inflammation. Although the loss of GH responsiven
Externí odkaz:
https://doaj.org/article/48b8fbeaed8f48a5ae45a5b6495525b6
Publikováno v:
Cellular Physiology and Biochemistry, Vol 50, Iss 4, Pp 1574-1584 (2018)
Background/Aims: Fibronectin type III domain-containing protein 5 (FNDC5), also known as irisin, is a myokine secreted from muscle in response to exercise. However, the molecular mechanisms that regulate FNDC5 expression and the functional significan
Externí odkaz:
https://doaj.org/article/e973227504af4ba28ca4a257c4902ff6
Publikováno v:
The American Journal of Clinical Nutrition. 116:15-39
Publikováno v:
Mol Psychiatry
Diabetes is a risk factor for Alzheimer's disease (AD), which is also called type 3 diabetes with insulin reduction and insulin resistance in AD patient brains. However, the molecular mechanism coupling diabetes to AD onset remains incompletely under