Zobrazeno 1 - 10
of 345
pro vyhledávání: '"Chi ZHU"'
Autor:
Li Zhuang, Chi Zhu, Jincheng Ma, Dan Zhu, Hengkai Zhu, Siyi Zhong, Xiangyan Liu, Zhuoyi Wang, Zhe Yang, Wu Zhang, Ran Ding, Dongsheng Chen, Shusen Zheng
Publikováno v:
Heliyon, Vol 10, Iss 16, Pp e36405- (2024)
Objective: To evaluate the predictive performance of metagenomic next-generation sequencing (mNGS) in identifying and predicting pulmonary infections following liver transplantation and to investigate its association with patient outcomes within the
Externí odkaz:
https://doaj.org/article/5a06d45336c64632bb2a3af6be68bf52
Autor:
Jing Zhang, Lin Gao, Chi Zhu, Jiajia Jin, Chao Song, Hang Dong, Zhenzhong Li, Zheng Wang, Yubao Chen, Zhenhua Yang, Yan Tan, Li Wang
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
Externí odkaz:
https://doaj.org/article/f09e9e91f3374785b0405a33f2eac5a9
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
ObjectiveTo evaluate the diagnostic value of metagenomic sequencing technology based on Illumina and Nanopore sequencing platforms for patients with suspected lower respiratory tract infection whose pathogen could not be identified by conventional mi
Externí odkaz:
https://doaj.org/article/d7bb3b9917274873814a064b15e04994
Autor:
Scott B. Biering, Francielle Tramontini Gomes de Sousa, Laurentia V. Tjang, Felix Pahmeier, Chi Zhu, Richard Ruan, Sophie F. Blanc, Trishna S. Patel, Caroline M. Worthington, Dustin R. Glasner, Bryan Castillo-Rojas, Venice Servellita, Nicholas T. N. Lo, Marcus P. Wong, Colin M. Warnes, Daniel R. Sandoval, Thomas Mandel Clausen, Yale A. Santos, Douglas M. Fox, Victoria Ortega, Anders M. Näär, Ralph S. Baric, Sarah A. Stanley, Hector C. Aguilar, Jeffrey D. Esko, Charles Y. Chiu, John E. Pak, P. Robert Beatty, Eva Harris
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Severe COVID-19 is associated with epithelial and endothelial barrier dysfunction, however, the molecular pathways resulting in endothelial barrier dysfunction and vascular leakage are only sparsely understood. Here, Biering et al. show that SARS-CoV
Externí odkaz:
https://doaj.org/article/4d267ba8c95f4d14abd51985e3d493fd
Autor:
Xammy Nguyenla, Eddie Wehri, Erik Van Dis, Scott B. Biering, Livia H. Yamashiro, Chi Zhu, Julien Stroumza, Claire Dugast-Darzacq, Thomas G. W. Graham, Xuanting Wang, Steffen Jockusch, Chuanjuan Tao, Minchen Chien, Wei Xie, Dinshaw J. Patel, Cindy Meyer, Aitor Garzia, Thomas Tuschl, James J. Russo, Jingyue Ju, Anders M. Näär, Sarah Stanley, Julia Schaletzky
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract SARS coronavirus 2 (SARS-CoV-2) has caused an ongoing global pandemic with significant mortality and morbidity. At this time, the only FDA-approved therapeutic for COVID-19 is remdesivir, a broad-spectrum antiviral nucleoside analog. Efficac
Externí odkaz:
https://doaj.org/article/9e4aeb4597b84bd5b8c7f7298e96338a
Autor:
Chi Zhu, Justin Y. Lee, Jia Z. Woo, Lei Xu, Xammy Nguyenla, Livia H. Yamashiro, Fei Ji, Scott B. Biering, Erik Van Dis, Federico Gonzalez, Douglas Fox, Eddie Wehri, Arjun Rustagi, Benjamin A. Pinsky, Julia Schaletzky, Catherine A. Blish, Charles Chiu, Eva Harris, Ruslan I. Sadreyev, Sarah Stanley, Sakari Kauppinen, Silvi Rouskin, Anders M. Näär
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Despite approved vaccines and anti-virals to prevent and treat SARS-CoV-2 infection, there is a need for further development of efficient antiviral therapeutic strategy. Here, Zhu et al. develop locked nucleic acid antisense oligonucleotides (LNA ASO
Externí odkaz:
https://doaj.org/article/465980a86b3646a5914f997d2bfea608
Autor:
Kiyoshi Yamaguchi, Saya Nakagawa, Akari Saku, Yumiko Isobe, Rui Yamaguchi, Paul Sheridan, Kiyoko Takane, Tsuneo Ikenoue, Chi Zhu, Masashi Miura, Yuya Okawara, Satoru Nagatoishi, Hiroko Kozuka-Hata, Masaaki Oyama, Susumu Aikou, Yuka Ahiko, Dai Shida, Kouhei Tsumoto, Satoru Miyano, Seiya Imoto, Yoichi Furukawa
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106563- (2023)
Summary: Bromodomain-containing protein 8 (BRD8) is a subunit of the NuA4/TIP60-histone acetyltransferase complex. Although BRD8 has been considered to act as a co-activator of the complex, its biological role remains to be elucidated. Here, we uncov
Externí odkaz:
https://doaj.org/article/40eae7249af94873810670d3565eb286
Autor:
Hui Yang, Xinzhi Wang, Pin Wang, Li He, Suzyann F. Schick, Peyton Jacob, III, Neal Benowitz, Lara A. Gundel, Chi Zhu, Yankai Xia, Jamie L. Inman, Hang Chang, Antoine M. Snijders, Jian-Hua Mao, Bo Hang
Publikováno v:
Environment International, Vol 174, Iss , Pp 107876- (2023)
Increasing evidence has shown that thirdhand smoke (THS) exposure is likely to induce adverse health effects. An important knowledge gap remains in our understanding of THS exposure related to cancer risk in the human population. Population-based ani
Externí odkaz:
https://doaj.org/article/f9446a229d244f1b988a422f110d0d69
Autor:
Zheng Wang, Chen Chen, Hu Lu, Li Wang, Lin Gao, Jing Zhang, Chi Zhu, Furong Du, Lunbiao Cui, Yan Tan
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
BackgroundWith the development of metagenomic sequencing technologies, more and more cases of pneumonia caused with Chlamydia psittaci (C. psittaci) have been reported. However, it remains unknown about the characteristics of patients with pneumonia
Externí odkaz:
https://doaj.org/article/b32e94235cd643bbbb23d1ced64af8b2
Autor:
Tammy C. T. Lan, Matty F. Allan, Lauren E. Malsick, Jia Z. Woo, Chi Zhu, Fengrui Zhang, Stuti Khandwala, Sherry S. Y. Nyeo, Yu Sun, Junjie U. Guo, Mark Bathe, Anders Näär, Anthony Griffiths, Silvi Rouskin
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Lan et al. report RNA structure ensembles across the entire SARSCoV-2 genome in infected human cells at single nucleotide resolution. They find alternative RNA conformations critical for promoting near-native frameshifting rates in ORF1ab.
Externí odkaz:
https://doaj.org/article/a24301ced5994fcabcdc3524241e53c4