Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Chi Wang Ip"'
Autor:
Alexander Grotemeyer, Tobias Petschner, Robert Peach, Dirk Hoehl, Torsten Knauer, Uwe Thomas, Heinz Endres, Robert Blum, Michael Sendtner, Jens Volkmann, Chi Wang Ip
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract Deep brain stimulation (DBS) has emerged as a revolutionary technique for accessing and modulating brain circuits. DBS is used to treat dysfunctional neuronal circuits in neurological and psychiatric disorders. Despite over two decades of cl
Externí odkaz:
https://doaj.org/article/bb635c25d976430f86ad5ec0e9bcce7c
Autor:
Maximilian U. Friedrich, Anna-Julia Roenn, Chiara Palmisano, Jane Alty, Steffen Paschen, Guenther Deuschl, Chi Wang Ip, Jens Volkmann, Muthuraman Muthuraman, Robert Peach, Martin M. Reich
Publikováno v:
npj Digital Medicine, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Tremor is one of the most common neurological symptoms. Its clinical and neurobiological complexity necessitates novel approaches for granular phenotyping. Instrumented neurophysiological analyses have proven useful, but are highly resource-
Externí odkaz:
https://doaj.org/article/6197af9fa18c40d88cf252cc4476b262
Autor:
Robert Peach, Maximilian Friedrich, Lara Fronemann, Muthuraman Muthuraman, Sebastian R. Schreglmann, Daniel Zeller, Christoph Schrader, Joachim K. Krauss, Alfons Schnitzler, Matthias Wittstock, Ann-Kristin Helmers, Steffen Paschen, Andrea Kühn, Inger Marie Skogseid, Wilhelm Eisner, Joerg Mueller, Cordula Matthies, Martin Reich, Jens Volkmann, Chi Wang Ip
Publikováno v:
npj Digital Medicine, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract Dystonia is a neurological movement disorder characterised by abnormal involuntary movements and postures, particularly affecting the head and neck. However, current clinical assessment methods for dystonia rely on simplified rating scales w
Externí odkaz:
https://doaj.org/article/0fbad953609640cea57e36f47712b111
Autor:
Susanne Knorr, Lisa Rauschenberger, Muthuraman Muthuraman, Rhonda McFleder, Thomas Ott, Kathrin Grundmann-Hauser, Takahiro Higuchi, Jens Volkmann, Chi Wang Ip
Publikováno v:
Neurobiology of Disease, Vol 194, Iss , Pp 106462- (2024)
DYT-TOR1A (DYT1) dystonia, characterized by reduced penetrance and suspected environmental triggers, is explored using a “second hit” DYT-TOR1A rat model. We aim to investigate the biological mechanisms driving the conversion into a dystonic phen
Externí odkaz:
https://doaj.org/article/e3e0427f360e46b5810d1e70a6ce8c05
Autor:
Rhonda L. McFleder, Anastasiia Makhotkina, Janos Groh, Ursula Keber, Fabian Imdahl, Josefina Peña Mosca, Alina Peteranderl, Jingjing Wu, Sawako Tabuchi, Jan Hoffmann, Ann-Kathrin Karl, Axel Pagenstecher, Jörg Vogel, Andreas Beilhack, James B. Koprich, Jonathan M. Brotchie, Antoine-Emmanuel Saliba, Jens Volkmann, Chi Wang Ip
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Inflammation in the brain and gut is a critical component of several neurological diseases, such as Parkinson’s disease (PD). One trigger of the immune system in PD is aggregation of the pre-synaptic protein, α-synuclein (αSyn). Understa
Externí odkaz:
https://doaj.org/article/64b3f60bf6a74cc880822e0307d481d0
Autor:
Colette Reinhold, Susanne Knorr, Rhonda L. McFleder, Lisa Rauschenberger, Muthuraman Muthuraman, Panagiota Arampatzi, Tom Gräfenhan, Andreas Schlosser, Michael Sendtner, Jens Volkmann, Chi Wang Ip
Publikováno v:
Neurobiology of Disease, Vol 193, Iss , Pp 106453- (2024)
DYT-TOR1A dystonia is the most common monogenic dystonia characterized by involuntary muscle contractions and lack of therapeutic options. Despite some insights into its etiology, the disease's pathophysiology remains unclear. The reduced penetrance
Externí odkaz:
https://doaj.org/article/75730ac91a984c17901626e8ba00be1c
Autor:
Lisa Rauschenberger, Chi Wang Ip
Publikováno v:
Dystonia, Vol 3 (2024)
Dystonia is a network disorder presumed to result from abnormalities in multiple brain regions and in multiple cell populations. The specific pathomechanisms affecting the motor circuits in dystonia are, however, still largely unclear. Animal models
Externí odkaz:
https://doaj.org/article/d7060f18edbf42579eee5c4e79e7e23e
Autor:
Chi Wang Ip, Jörg Wischhusen
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-3 (2023)
Externí odkaz:
https://doaj.org/article/6457ef39e34742f79d1a276a8dce10b0
Autor:
Alexander Grotemeyer, Judith F. Fischer, James B. Koprich, Jonathan M. Brotchie, Robert Blum, Jens Volkmann, Chi Wang Ip
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-14 (2023)
Abstract Neuroinflammation has been suggested as a pathogenetic mechanism contributing to Parkinson’s disease (PD). However, anti-inflammatory treatment strategies have not yet been established as a therapeutic option for PD patients. We have used
Externí odkaz:
https://doaj.org/article/940753474ea54cd0aeec7126dbf86613
Autor:
Venkata C Chirumamilla, Chi Wang Ip, Martin Reich, Robert Peach, Jens Volkmann, Bahman Nasseroleslami, Muthuraman Muthuraman
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 9, Pp 1879-1880 (2024)
Externí odkaz:
https://doaj.org/article/adee242393064eca9dbaad863541ef25