Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Chi Wai Yip"'
Autor:
Nejc Haberman, Holly Digby, Rupert Faraway, Rebecca Cheung, Anob M. Chakrabarti, Andrew M. Jobbins, Callum Parr, Kayoko Yasuzawa, Takeya Kasukawa, Chi Wai Yip, Masaki Kato, Hazuki Takahashi, Piero Carninci, Santiago Vernia, Jernej Ule, Christopher R. Sibley, Aida Martinez-Sanchez, Boris Lenhard
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-23 (2024)
Abstract The 3′ untranslated region (3′UTR) plays a crucial role in determining mRNA stability, localisation, translation and degradation. Cap analysis of gene expression (CAGE), a method for the detection of capped 5′ ends of mRNAs, additional
Externí odkaz:
https://doaj.org/article/ad037dcdd70a4cf1aefd83bb7b5773ce
Autor:
Saumya Agrawal, Andrey Buyan, Jessica Severin, Masaru Koido, Tanvir Alam, Imad Abugessaisa, Howard Y Chang, Josée Dostie, Masayoshi Itoh, Juha Kere, Naoto Kondo, Yunjing Li, Vsevolod J Makeev, Mickaël Mendez, Yasushi Okazaki, Jordan A Ramilowski, Andrey I Sigorskikh, Lisa J Strug, Ken Yagi, Kayoko Yasuzawa, Chi Wai Yip, Chung Chau Hon, Michael M Hoffman, Chikashi Terao, Ivan V Kulakovskiy, Takeya Kasukawa, Jay W Shin, Piero Carninci, Michiel J L de Hoon
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0295971 (2024)
The human genome is pervasively transcribed and produces a wide variety of long non-coding RNAs (lncRNAs), constituting the majority of transcripts across human cell types. Some specific nuclear lncRNAs have been shown to be important regulatory comp
Externí odkaz:
https://doaj.org/article/cd55b6045f20467eb83991410871c30d
Autor:
Phyllis F. Cheung, JiaJin Yang, Rui Fang, Arianna Borgers, Kirsten Krengel, Anne Stoffel, Kristina Althoff, Chi Wai Yip, Elaine H. L. Siu, Linda W. C. Ng, Karl S. Lang, Lamin B. Cham, Daniel R. Engel, Camille Soun, Igor Cima, Björn Scheffler, Jana K. Striefler, Marianne Sinn, Marcus Bahra, Uwe Pelzer, Helmut Oettle, Peter Markus, Esther M. M. Smeets, Erik H. J. G. Aarntzen, Konstantinos Savvatakis, Sven-Thorsten Liffers, Smiths S. Lueong, Christian Neander, Anna Bazarna, Xin Zhang, Annette Paschen, Howard C. Crawford, Anthony W. H. Chan, Siu Tim Cheung, Jens T. Siveke
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Immune responses to pancreatic ductal adenocarcinoma can be inhibited by cancer cells. Here the authors show that high levels of progranulin in PDAC inhibits immune responses by reducing MHC class I antigen presentation through enhanced degradation o
Externí odkaz:
https://doaj.org/article/c9aa189db2194c2eba13f30f461a6fdd
Autor:
Chi Wai Yip, Ching Yan Lam, Terence C. W. Poon, Tan To Cheung, Phyllis F. Y. Cheung, Sze Wai Fung, Xiao Qi Wang, Idy C.Y. Leung, Linda W. C. Ng, Chung Mau Lo, George S. W. Tsao, Siu Tim Cheung
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-8 (2017)
Abstract Background Granulin-epithelin precursor (GEP) is a secretory growth factor, which has been demonstrated to control cancer growth, invasion, drug resistance and immune escape. Our previous studies and others also demonstrated its potential in
Externí odkaz:
https://doaj.org/article/6bc88201718349b7a6a31d705161c1dd
Autor:
Ching Yan Lam, Chi Wai Yip, Terence C W Poon, Christine K C Cheng, Eddy W Y Ng, Nicholas C L Wong, Phyllis F Y Cheung, Paul B S Lai, Irene O L Ng, Sheung Tat Fan, Siu Tim Cheung
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40324 (2012)
BACKGROUND AND AIM: Granulin-epithelin precursor (GEP) has previously been reported to control cancer growth, invasion, chemo-resistance, and served as novel therapeutic target for cancer treatment. However, the nature and characteristics of GEP inte
Externí odkaz:
https://doaj.org/article/f149f9647d2245889a6f20ab06cf103c
Autor:
Phyllis Fung Yi Cheung, Christine Kei Chin Cheng, Nicholas Chun Lim Wong, Jenny Chung Yee Ho, Chi Wai Yip, Vincent Chi Hang Lui, Annie Nga Yin Cheung, Sheung Tat Fan, Siu Tim Cheung
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28246 (2011)
BACKGROUND AND AIMS: Increasing evidence has suggested that hepatocellular carcinoma (HCC) might originate from a distinct subpopulation called cancer stem cells (CSCs), which are responsible for the limited efficacy of conventional therapies. We hav
Externí odkaz:
https://doaj.org/article/a22462a0fb054dd18d32b07ae945b344
Autor:
Nejc Haberman, Holly Digby, Rupert Faraway, Rebecca Cheung, Andrew M Jobbins, Callum Parr, Kayoko Yasuzawa, Takeya Kasukawa, Chi Wai Yip, Masaki Kato, Hazuki Takahashi, Piero Carninci, Santiago Vernia, Jernej Ule, Christopher R Sibley, Aida Martinez-Sanchez, Boris Lenhard
SummaryThe 3’ untranslated region (3’UTR) plays a crucial role in determining mRNA stability, localisation, translation and degradation. Cap analysis gene expression (CAGE), a method for the detection of capped 5’ ends of mRNAs, additionally re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18bb72c57a82b070076c02347f548466
http://hdl.handle.net/10044/1/105362
http://hdl.handle.net/10044/1/105362
Autor:
Siu Tim Cheung, Sheung Tat Fan, Irene Oi-Lin Ng, Kui Fat Chan, Chi Wai Yip, Phyllis F.Y. Cheung, Nicholas C.L. Wong
Supplementary Figure S1: IgG negative control demonstrated no added effect on the chemotherapy induced apoptosis; Supplementary Figure S2: Secretory GEP levels in Hep3B and Huh7 culture supernatants; Supplementary Figure S3: Combined GEP antibody and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2af2897db753ab52b5ab82a4d7b51f48
https://doi.org/10.1158/1535-7163.22502074
https://doi.org/10.1158/1535-7163.22502074
Autor:
Siu Tim Cheung, Sheung Tat Fan, Ronnie T.P. Poon, Irene O.L. Ng, Tan To Cheung, Chun Kwok Wong, Angus M.Y. Wan, Linda W.C. Ng, Daniel Y.T. Fong, Nicholas C.L. Wong, Chi Wai Yip, Phyllis F.Y. Cheung
Immunoevasion is an emerging hallmark of cancer. Impairment of natural killer (NK) cytotoxicity is a mechanism to evade host immunosurveillance. Granulin–epithelin precursor (GEP) is a hepatic oncofetal protein regulating growth, invasion, and chem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5947d5135f01e70b350df69570bde58b
https://doi.org/10.1158/2326-6066.c.6548260.v1
https://doi.org/10.1158/2326-6066.c.6548260.v1
Autor:
Siu Tim Cheung, Sheung Tat Fan, Ronnie T.P. Poon, Irene O.L. Ng, Tan To Cheung, Chun Kwok Wong, Angus M.Y. Wan, Linda W.C. Ng, Daniel Y.T. Fong, Nicholas C.L. Wong, Chi Wai Yip, Phyllis F.Y. Cheung
Supplementary Table 1. Clinico-pathological features of HCC in relation to sGEP and sMICA levels. Supplementary Table 2. Cox regression analyses for recurrence-free survival on sGEP/sMICA levels and tumor stage. Supplementary Figure 1. Cytotoxicity o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3251c8e3a0ee526ad1013cb15410d846
https://doi.org/10.1158/2326-6066.22536886.v1
https://doi.org/10.1158/2326-6066.22536886.v1