Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Chi W Pak"'
Autor:
Jianjie Mi, Alisa E Shaw, Chi W Pak, Keifer P Walsh, Laurie S Minamide, Barbara W Bernstein, Thomas B Kuhn, James R Bamburg
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e83609 (2013)
Filament bundles (rods) of cofilin and actin (1:1) form in neurites of stressed neurons where they inhibit synaptic function. Live-cell imaging of rod formation is hampered by the fact that overexpression of a chimera of wild type cofilin with a fluo
Externí odkaz:
https://doaj.org/article/6b6af92becf44f2bb4468f3c52a3554d
Autor:
Ali A. Yunus, Michael K. Rosen, Rustam Ali, David R. Liu, Anuradha Mittal, Alex S. Holehouse, Martyna Kosno, Chi W. Pak, Rohit V. Pappu, Shae B. Padrick
Publikováno v:
Molecular Cell. 63:72-85
Liquid-liquid phase separation, driven by collective interactions among multivalent and intrinsically disordered proteins, is thought to mediate the formation of membrane-less organelles in cells. Using parallel cellular and in vitro assays, we show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b81ac7eb6c3ac8e3efddfc3fd5cda93f
https://doi.org/10.1016/j.molcel.2016.05.042
https://doi.org/10.1016/j.molcel.2016.05.042
Autor:
Chi W. Pak, Diana R. Tomchick, Zhucheng Chen, Ali A. Yunus, Shae B. Padrick, Zhe Chen, Michael K. Rosen, Lisa Henry, Jacob A. Zahm
Publikováno v:
Cell. 155:423-434
Bacterial pathogens use secreted effector proteins to subvert host-cell defenses. VopL is an effector protein from Vibrio parahaemolyticus that nucleates actin filaments. VopL consists of a VopL C-terminal Domain (VCD) and a tandem array of three WAS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc695a1ab2b0f82277ed4327b44a1f5a
https://doi.org/10.1016/j.cell.2013.09.019
https://doi.org/10.1016/j.cell.2013.09.019
Autor:
J. R. Jensen, James R. Bamburg, Alisa E. Shaw, Michael T. Maloney, Ian T. Marsden, Barbara W. Bernstein, Kevin C. Flynn, Claire Goldsbury, Ineka T. Whiteman, O'Neil Wiggan, Laurie S. Minamide, Richard C. Davis, Chi W. Pak
Publikováno v:
Current Alzheimer Research. 7:241-250
Dephosphorylation (activation) of cofilin, an actin binding protein, is stimulated by initiators of neuronal dysfunction and degeneration including oxidative stress, excitotoxic glutamate, ischemia, and soluble forms of beta-amyloid peptide (Abeta).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a071efc112c289a2f9c07570dc9d82b1
https://doi.org/10.2174/156720510791050902
https://doi.org/10.2174/156720510791050902
Autor:
James R. Bamburg, Chi W. Pak
Publikováno v:
The Open Neuroscience Journal. 3:52-153
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17aab3731636df8267e39e79c4f851a5
https://doi.org/10.2174/1874082000903010052
https://doi.org/10.2174/1874082000903010052
Publikováno v:
Developmental Neurobiology. 69:761-779
Axonogenesis involves a shift from uniform delivery of materials to all neurites to preferential delivery to the putative axon, supporting its more rapid extension. Waves, growth cone-like structures that propagate down the length of neurites, were s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4596b4be96e46b33a5b5d5738bd76a59
https://doi.org/10.1002/dneu.20734
https://doi.org/10.1002/dneu.20734
Publikováno v:
Journal of Theoretical Biology. 252:173-183
Recent observations of F-actin dynamics call for theoretical models to interpret and understand the quantitative data. A number of existing models rely on simplifications and do not take into account F-actin fragmentation and annealing. We use Gilles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e01bad3ce8ace24996aa7d24ec7941e1
https://doi.org/10.1016/j.jtbi.2008.01.001
https://doi.org/10.1016/j.jtbi.2008.01.001
Publikováno v:
Nature Reviews Neuroscience. 9:136-147
Higher-order actin-based networks (actin superstructures) are important for growth-cone motility and guidance. Principles for generating, organizing and remodelling actin superstructures have emerged from recent findings in cell-free systems, non-neu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36d927fb14dd5d4031c9ddef60adaadd
https://doi.org/10.1038/nrn2236
https://doi.org/10.1038/nrn2236
Autor:
Yuxing Liao, Shuoyong Shi, Klaus Brinkmann, Sven Bogdan, Chi W. Pak, Baoyu Chen, Zhucheng Chen, Michael K. Rosen, Lisa Henry, Nick V. Grishin
Publikováno v:
Cell. 156(1-2)
SummaryThe WAVE regulatory complex (WRC) controls actin cytoskeletal dynamics throughout the cell by stimulating the actin-nucleating activity of the Arp2/3 complex at distinct membrane sites. However, the factors that recruit the WRC to specific loc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1113359dc4e5c45e7a804779ffd4f11
https://pubmed.ncbi.nlm.nih.gov/24439365
https://pubmed.ncbi.nlm.nih.gov/24439365
Autor:
Barbara W. Bernstein, Keifer P. Walsh, Alisa E. Shaw, Chi W. Pak, James R. Bamburg, Jianjie Mi, Thomas Kuhn, Laurie S. Minamide
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e83609 (2013)
PLoS ONE
PLoS ONE
Filament bundles (rods) of cofilin and actin (1:1) form in neurites of stressed neurons where they inhibit synaptic function. Live-cell imaging of rod formation is hampered by the fact that overexpression of a chimera of wild type cofilin with a fluo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a69b415f55935f8168b4ad459db2aaf
http://europepmc.org/articles/PMC3877059?pdf=render
http://europepmc.org/articles/PMC3877059?pdf=render