Newly synthesised oxime and lactone derivatives from Dipterocarpus alatus dipterocarpol as anti-diabetic inhibitors: experimental bioassay-based evidence and theoretical computation-based prediction.

Autor: Phuong Thao TT; Institute of Chemistry, Vietnam Academy of Science and Technology (VAST) 18 Hoang Quoc Viet Road, Cau Giay Ha Noi Vietnam tranvansungvhh@gmail.com.; Graduate University of Science and Technology, VAST 18 Hoang Quoc Viet Road, Cau Giay Ha Noi Vietnam., Bui TQ; Department of Chemistry, University of Sciences, Hue University Hue City Vietnam ntanhung@hueuni.edu.vn., Thi Thanh Hai N; Department of Chemistry, University of Sciences, Hue University Hue City Vietnam ntanhung@hueuni.edu.vn., Huynh LK; International University Quarter 6, Linh Trung Ward, Thu Duc District Ho Chi Minh City Vietnam.; Vietnam National University Ho Chi Minh City Vietnam., Quy PT; Department of Natural Sciences & Technology, Tay Nguyen University Buon Ma Thuot Vietnam., Bao NC; Hue University Hue City Vietnam., Dung NT; Institute of Chemistry, Vietnam Academy of Science and Technology (VAST) 18 Hoang Quoc Viet Road, Cau Giay Ha Noi Vietnam tranvansungvhh@gmail.com., Chi NL; Institute of Chemistry, Vietnam Academy of Science and Technology (VAST) 18 Hoang Quoc Viet Road, Cau Giay Ha Noi Vietnam tranvansungvhh@gmail.com.; Graduate University of Science and Technology, VAST 18 Hoang Quoc Viet Road, Cau Giay Ha Noi Vietnam., Van Loc T; Institute of Chemistry, Vietnam Academy of Science and Technology (VAST) 18 Hoang Quoc Viet Road, Cau Giay Ha Noi Vietnam tranvansungvhh@gmail.com.; Graduate University of Science and Technology, VAST 18 Hoang Quoc Viet Road, Cau Giay Ha Noi Vietnam., Smirnova IE; Ufa Institute of Chemistry-Subdivision of the Ufa Federal Research Centre of the Russian Academy of Sciences Prospekt Oktyabrya 71 Ufa Russian Federation., Petrova AV; Ufa Institute of Chemistry-Subdivision of the Ufa Federal Research Centre of the Russian Academy of Sciences Prospekt Oktyabrya 71 Ufa Russian Federation., Ninh PT; Institute of Chemistry, Vietnam Academy of Science and Technology (VAST) 18 Hoang Quoc Viet Road, Cau Giay Ha Noi Vietnam tranvansungvhh@gmail.com.; Graduate University of Science and Technology, VAST 18 Hoang Quoc Viet Road, Cau Giay Ha Noi Vietnam., Van Sung T; Institute of Chemistry, Vietnam Academy of Science and Technology (VAST) 18 Hoang Quoc Viet Road, Cau Giay Ha Noi Vietnam tranvansungvhh@gmail.com.; Graduate University of Science and Technology, VAST 18 Hoang Quoc Viet Road, Cau Giay Ha Noi Vietnam., Nhung NTA; Department of Chemistry, University of Sciences, Hue University Hue City Vietnam ntanhung@hueuni.edu.vn.

Publikováno v: RSC advances [RSC Adv] 2021 Nov 04; Vol. 11 (57), pp. 35765-35782. Date of Electronic Publication: 2021 Nov 04 (Print Publication: 2021).

A unique CDK4/6 inhibitor: Current and future therapeutic strategies of abemaciclib.

Autor: Chong QY; Cancer Science Institute of Singapore, National University of Singapore, Singapore., Kok ZH; Cancer Science Institute of Singapore, National University of Singapore, Singapore., Bui NL; Cancer Science Institute of Singapore, National University of Singapore, Singapore., Xiang X; Department of Clinical Pharmacy, School of Pharmacy, Fudan University, Shanghai, China., Wong AL; Cancer Science Institute of Singapore, National University of Singapore, Singapore; Department of Haematology-Oncology, National University Cancer Institute Singapore, National University Health System, Singapore., Yong WP; Cancer Science Institute of Singapore, National University of Singapore, Singapore; Department of Haematology-Oncology, National University Cancer Institute Singapore, National University Health System, Singapore., Sethi G; Department of Pharmacology, National University of Singapore, Singapore., Lobie PE; Cancer Science Institute of Singapore, National University of Singapore, Singapore; Tsinghua Berkeley Shenzhen Institute (TBSI), Tsinghua University, Shenzhen, China., Wang L; Cancer Science Institute of Singapore, National University of Singapore, Singapore; Department of Haematology-Oncology, National University Cancer Institute Singapore, National University Health System, Singapore. Electronic address: csiwl@nus.edu.sg., Goh BC; Cancer Science Institute of Singapore, National University of Singapore, Singapore; Department of Haematology-Oncology, National University Cancer Institute Singapore, National University Health System, Singapore; Department of Pharmacology, National University of Singapore, Singapore; Department of Medicine, National University Cancer Institute Singapore, National University Health System, Singapore. Electronic address: phcgbc@nus.edu.sg.

Publikováno v: Pharmacological research [Pharmacol Res] 2020 Jun; Vol. 156, pp. 104686. Date of Electronic Publication: 2020 Feb 14.

Bad phosphorylation as a target of inhibition in oncology.

Autor: Bui NL; Cancer Science Institute of Singapore, National University of Singapore, Singapore., Pandey V; Tsinghua Berkeley Shenzhen Institute, Tsinghua University, Shenzhen, Guangdong, PR China., Zhu T; Hefei National Laboratory for Physical Sciences at Microscale and School of Life Sciences, University of Science and Technology of China, Hefei, Anhui, China; The CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences, University of Science and Technology of China, Hefei, Anhui, China., Ma L; Tsinghua Berkeley Shenzhen Institute, Tsinghua University, Shenzhen, Guangdong, PR China., Basappa; Laboratory of Chemical Biology, Department of Studies in Organic Chemistry, University of Mysore, Manasagangotri, Mysore, 570006, India., Lobie PE; Cancer Science Institute of Singapore, National University of Singapore, Singapore; Tsinghua Berkeley Shenzhen Institute, Tsinghua University, Shenzhen, Guangdong, PR China; National University Cancer Institute, National University Health System, Singapore. Electronic address: pelobie@sz.tsinghua.edu.cn.

Publikováno v: Cancer letters [Cancer Lett] 2018 Feb 28; Vol. 415, pp. 177-186. Date of Electronic Publication: 2017 Nov 23.