Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Chi Ming Laurence Lau"'
Autor:
Yu Yu, Derek Wai Yee Chow, Chi Ming Laurence Lau, Guanqun Zhou, Woojin Back, Jing Xu, Sean Carim, Ying Chau
Publikováno v:
Bioengineering & Translational Medicine, Vol 6, Iss 3, Pp n/a-n/a (2021)
Abstract Natural soft hydrogels are unique elastic soft materials utilized by living organisms for protecting delicate tissues. Under a theoretical framework derived from the Blob model, we chemically crosslinked high molecular weight hyaluronic acid
Externí odkaz:
https://doaj.org/article/8869c731845048fb8c03024ff94076aa
Publikováno v:
ACS biomaterials scienceengineering. 8(10)
A three-dimensional lattice-based model has been developed to describe the release of a macromolecular drug encapsulated in a degradable hydrogel. The degradation-induced network heterogeneity is considered by assigning varying diffusion coefficients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83cab57be61df5a31c619f27cc4537b2
https://pubmed.ncbi.nlm.nih.gov/36057096
https://pubmed.ncbi.nlm.nih.gov/36057096
Publikováno v:
Acta Biomaterialia. 101:219-226
We have demonstrated the use of a simple 1H NMR spectrometry-based method to directly measure the pseudo first-order hydrolytic cleavage rate constant (kobs) of methacrylate-derived ester crosslinkers in hydrogels composed of PEG, dextran, carboxymet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8c92bb8bfc1129f9680050d67aedb1d
https://doi.org/10.1016/j.actbio.2019.10.030
https://doi.org/10.1016/j.actbio.2019.10.030
Publikováno v:
ACS applied bio materials. 3(7)
A three-dimensional model has been developed to describe the multiphase release of macromolecular drugs encapsulated in a hydrogel. The heterogeneity of network mesh size was considered by assigning varying diffusion coefficients to the network latti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a170f8c3f261be359c8364eeed301b2f
https://pubmed.ncbi.nlm.nih.gov/35025422
https://pubmed.ncbi.nlm.nih.gov/35025422
Autor:
Shuhuai Yao, Yuzi Zhang, Jin Teng Chung, Ying Chau, Casper Ho Yin Chung, Chi Ming Laurence Lau, Dixon T. Sin
Publikováno v:
ACS applied bio materials. 4(8)
Hydrogel microparticles (HMPs) have been widely applied in biological, pharmacologic, and biomedical industries due to their versatility. Particle size is a paramount factor for controlling drug release profiles from HMPs. Conventional fabrication me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::865d46ab690a85a557afdc1f91d67ff6
https://pubmed.ncbi.nlm.nih.gov/35006890
https://pubmed.ncbi.nlm.nih.gov/35006890
Autor:
Sean Carim, Guanqun Zhou, Jing Xu, Yu Yu, Woo Jin Back, Chi Ming Laurence Lau, Derek Wai Yee Chow, Ying Chau
Publikováno v:
Bioengineering & Translational Medicine, Vol 6, Iss 3, Pp n/a-n/a (2021)
Bioengineering & Translational Medicine
Bioengineering & Translational Medicine
Natural soft hydrogels are unique elastic soft materials utilized by living organisms for protecting delicate tissues. Under a theoretical framework derived from the Blob model, we chemically crosslinked high molecular weight hyaluronic acid at a con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a03b156f71ed88bb1e0dfbce97fb61c
https://doaj.org/article/8869c731845048fb8c03024ff94076aa
https://doaj.org/article/8869c731845048fb8c03024ff94076aa
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 335
Using hydrogels to control the long-term release of protein remains challenging, especially for in-situ forming formulations. The uncontrollable burst release in the initial phase, the halted release in the subsequent phase, and the undesired drug du
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aef33577c17342a76fa38c0e4ac5076
https://pubmed.ncbi.nlm.nih.gov/33971140
https://pubmed.ncbi.nlm.nih.gov/33971140
Publikováno v:
Acta biomaterialia. 101
We have demonstrated the use of a simple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::caa3530468d21f6eacf37334ca251e69
https://pubmed.ncbi.nlm.nih.gov/31669542
https://pubmed.ncbi.nlm.nih.gov/31669542
Publikováno v:
Advanced drug delivery reviews. 126
Antiangiogenic therapeutics, such as corticosteroids, VEGF targeting antibodies and aptamers have been demonstrated effective in controlling retinal and choroidal neovascularization related vision loss. However, to manage the chronic conditions, it r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0116789accc4723c3e1f9d0ab3fd8aa9
https://pubmed.ncbi.nlm.nih.gov/29625138
https://pubmed.ncbi.nlm.nih.gov/29625138