Zobrazeno 1 - 10
of 125
pro vyhledávání: '"Chi Man, Tsang"'
Autor:
Man Wu, Pok Man Hau, Linxian Li, Chi Man Tsang, Yike Yang, Aziz Taghbalout, Grace Tin-Yun Chung, Shin Yee Hui, Wing Chung Tang, Nathaniel Jillette, Jacqueline Jufen Zhu, Horace Hok Yeung Lee, Ee Ling Kong, Melissa Sue Ann Chan, Jason Ying Kuen Chan, Brigette Buig Yue Ma, Mei-Ru Chen, Charles Lee, Ka Fai To, Albert Wu Cheng, Kwok-Wai Lo
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract The unique virus-cell interaction in Epstein-Barr virus (EBV)-associated malignancies implies targeting the viral latent-lytic switch is a promising therapeutic strategy. However, the lack of specific and efficient therapeutic agents to indu
Externí odkaz:
https://doaj.org/article/5ea7e874509d4bf389c2b2f00f71f2fc
Autor:
Bonan Chen, Xiaoli Liu, Peiyao Yu, Fuda Xie, Johnny S. H. Kwan, Wai Nok Chan, Canbin Fang, Jinglin Zhang, Alvin H. K. Cheung, Chit Chow, Gloria W. M. Leung, Kam Tong Leung, Shihua Shi, Bin Zhang, Shouyu Wang, Dazhi Xu, Kaili Fu, Chi Chun Wong, William K. K. Wu, Michael W. Y. Chan, Patrick M. K. Tang, Chi Man Tsang, Kwok Wai Lo, Gary M. K. Tse, Jun Yu, Ka Fai To, Wei Kang
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 11, Pp n/a-n/a (2023)
Abstract Background Gastric cancer (GC) is one of the most common tumours in East Asia countries and is associated with Helicobacter pylori infection. H. pylori utilizes virulence factors, CagA and VacA, to up‐regulate pro‐inflammatory cytokines
Externí odkaz:
https://doaj.org/article/7bfa61a822b64b09a39959da5d928f18
Autor:
Jeff P. Bruce, Ka-Fai To, Vivian W. Y. Lui, Grace T. Y. Chung, Yuk-Yu Chan, Chi Man Tsang, Kevin Y. Yip, Brigette B. Y. Ma, John K. S. Woo, Edwin P. Hui, Michael K. F. Mak, Sau-Dan Lee, Chit Chow, Sharmila Velapasamy, Yvonne Y. Y. Or, Pui Kei Siu, Samah El Ghamrasni, Stephenie Prokopec, Man Wu, Johnny S. H. Kwan, Yuchen Liu, Jason Y. K. Chan, C. Andrew van Hasselt, Lawrence S. Young, Christopher W. Dawson, Ian C. Paterson, Lee-Fah Yap, Sai-Wah Tsao, Fei-Fei Liu, Anthony T. C. Chan, Trevor J. Pugh, Kwok-Wai Lo
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
The genomic characterisation of nasopharyngeal carcinoma (NPC) remains crucial. Here, the authors perform whole-genome sequencing for 70 NPCs with EBV gene expression, report the somatic alterations and EBV-mediated effects converging on NF-κB activ
Externí odkaz:
https://doaj.org/article/84b65b92c11446b886dec64811b68199
Autor:
Matt Lechner, Volker H. Schartinger, Christopher D. Steele, Wen Long Nei, Marc Lucas Ooft, Liesa-Marie Schreiber, Christodoulos P. Pipinikas, Grace Tin-Yun Chung, Yuk Yu Chan, Feng Wu, Ka-Fai To, Chi Man Tsang, Wayne Pearce, Daniele Morelli, Martin Philpott, Liam Masterson, Reshma Nibhani, Graham Wells, Christopher G. Bell, Julia Koller, Susanne Delecluse, Yim Ling Yip, Jacklyn Liu, Cillian T. Forde, Martin D. Forster, Amrita Jay, József Dudás, Annika Krapp, Simon Wan, Christian Uprimny, Susanne Sprung, Johannes Haybaeck, Tim R. Fenton, Kerry Chester, Christina Thirlwell, Gary Royle, Teresa Marafioti, Rajeev Gupta, Sagung Rai Indrasari, Camelia Herdini, Mohd Afiq Mohd Slim, I. Indrawati, Liam Sutton, Renske Fles, Bing Tan, Joe Yeong, Amit Jain, Shuting Han, Haitao Wang, Kelvin S. H. Loke, Wan He, Ruilian Xu, Hongtao Jin, Zhiqiang Cheng, David Howard, Peter H. Hwang, Quynh-Thu Le, Joshua K. Tay, Robert B. West, Sai Wah Tsao, Tim Meyer, Herbert Riechelmann, Udo Oppermann, Henri-Jacques Delecluse, Stefan M. Willems, Melvin L. K. Chua, Pierre Busson, Kwok Wai Lo, Guido Wollmann, Nischalan Pillay, Bart Vanhaesebroeck, Valerie J. Lund
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Nasopharyngeal carcinoma (NPC) lacks effective diagnostic and therapeutic strategies, in particular at advanced stages. Here, the authors show that expression of the somatostatin receptor 2 is induced by Epstein-Barr virus in NPC and has a key role i
Externí odkaz:
https://doaj.org/article/ff5d4bfec0f74e349a04c2a36d9baae8
Autor:
Jianguo Wang, Qiang Jiang, Oluwasijibomi Damola Faleti, Chi-Man Tsang, Min Zhao, Gongfa Wu, Sai-Wah Tsao, Minyi Fu, Yuxiang Chen, Tengteng Ding, Tuotuo Chong, Yufei Long, Xu Yang, Yuanbin Zhang, Yunxi Cai, Hanzhao Li, Manli Peng, Xiaoming Lyu, Xin Li
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 22, Iss , Pp 153-165 (2020)
Nasopharyngeal carcinoma (NPC) is an Epstein-Barr virus (EBV)-associated cancer characterized by a high degree of recurrence, angiogenesis, and metastasis. The importance of alternative pro-angiogenesis pathways including viral factors has emerged af
Externí odkaz:
https://doaj.org/article/2219685c8b1e4c45a0bc201d78d950fc
Autor:
Philip Chiu‐Tsun Tang, Jeff Yat‐Fai Chung, Vivian Wei‐wen Xue, Jun Xiao, Xiao‐Ming Meng, Xiao‐Ru Huang, Shuang Zhou, Alex Siu‐Wing Chan, Anna Chi‐Man Tsang, Alfred Sze‐Lok Cheng, Tin‐Lap Lee, Kam‐Tong Leung, Eric W.‐F. Lam, Ka‐Fai To, Patrick Ming‐Kuen Tang, Hui‐Yao Lan
Publikováno v:
Advanced Science, Vol 9, Iss 1, Pp n/a-n/a (2022)
Abstract Cancer‐associated fibroblasts (CAFs) are important in tumor microenvironment (TME) driven cancer progression. However, CAFs are heterogeneous and still largely underdefined, better understanding their origins will identify new therapeutic
Externí odkaz:
https://doaj.org/article/88a2b3b2105e4c93a1fe6c6dfeb41b23
Autor:
Christian Benzing, Hoyin Lam, Chi Man Tsang, Alexander Rimmer, Yoana Arroyo-Berdugo, Yolanda Calle, Claire M. Wells
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-14 (2019)
Abstract Background Monocytes are a major component of the tumor microenvironment (TME) in pancreatic ductal adenocarcinoma (PDAC). However, the complex interactions between tumor cells and monocytes and their role in tumor invasion have not been ful
Externí odkaz:
https://doaj.org/article/f560872f34c64405b7258d44b284a3e7
Autor:
Jeff P. Bruce, Ka-Fai To, Vivian W. Y. Lui, Grace T. Y. Chung, Yuk-Yu Chan, Chi Man Tsang, Kevin Y. Yip, Brigette B. Y. Ma, John K. S. Woo, Edwin P. Hui, Michael K. F. Mak, Sau-Dan Lee, Chit Chow, Sharmila Velapasamy, Yvonne Y. Y. Or, Pui Kei Siu, Samah El Ghamrasni, Stephenie Prokopec, Man Wu, Johnny S. H. Kwan, Yuchen Liu, Jason Y. K. Chan, C. Andrew van Hasselt, Lawrence S. Young, Christopher W. Dawson, Ian C. Paterson, Lee-Fah Yap, Sai-Wah Tsao, Fei-Fei Liu, Anthony T. C. Chan, Trevor J. Pugh, Kwok-Wai Lo
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/f4c5624de0d740c496d631d66856f4cf
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Nasopharyngeal carcinoma (NPC) is consistently associated with Epstein-Barr virus (EBV) infection in regions in which it is endemic, including Southern China and Southeast Asia. The high mortality rates of NPC patients with advanced and recurrent dis
Externí odkaz:
https://doaj.org/article/abe559c8c29f415c818dc9d53fff1cec
Autor:
Xiaoming Lyu, Jianguo Wang, Xia Guo, Gongfa Wu, Yang Jiao, Oluwasijibomi Damola Faleti, Pengfei Liu, Tielian Liu, Yufei Long, Tuotuo Chong, Xu Yang, Jing Huang, Mingliang He, Chi Man Tsang, Sai Wah Tsao, Qian Wang, Qiang Jiang, Xin Li
Publikováno v:
PLoS Pathogens, Vol 16, Iss 4, p e1008532 (2020)
[This corrects the article DOI: 10.1371/journal.ppat.1007484.].
Externí odkaz:
https://doaj.org/article/291e39065d2e45e589c3f1e7a825e42a