Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Chi M. Woo"'
Publikováno v:
Journal of Medicinal Chemistry. 26:1109-1112
Various ethylenediamine derivatives have been incorporated into the nitrogen substituent of certain short-acting (aryloxy)propanolamine systems that contain esters on their aryl functions. Although several of these compounds showed durations of actio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d44aad30561c3cf2aed61aec8d96532d
https://doi.org/10.1021/jm00362a004
https://doi.org/10.1021/jm00362a004
Publikováno v:
Journal of Medicinal Chemistry. 25:1402-1407
In an attempt to produce short-acting beta-adrenergic receptor blocking agents, we prepared several (aryloxy)propanolamines with ester functions incorporated into the nitrogen substituent. Many of these compounds exhibited a short duration of blockin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acbd41db931627dc27e53a226bbd6684
https://doi.org/10.1021/jm00354a002
https://doi.org/10.1021/jm00354a002
Publikováno v:
Journal of Medicinal Chemistry. 21:340-343
Some dihydro- and hexahydro-2-dialkylaminoalkyl-9-phenyl-1H-indeno[2,1-c]pyridines were prepared and found to possess significant antiarrhythmic activity. Hydrogenation of the dihydro compounds 4 produced the allcis-hexahydro isomers 5 which were con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27ae826f3235222da6ad8c7a2f5bb913
https://doi.org/10.1021/jm00202a005
https://doi.org/10.1021/jm00202a005
Publikováno v:
Journal of Medicinal Chemistry. 21:952-957
2-Amino-4-aryl-3H-1,5-benzodiazepines were prepared and evaluated for potential neuroleptic activity. Compound 60 showed some activity in the four assays; however, the activity was not consistently observed among other members of the series. The data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a82a7b117b9ac5e1ab4c847bb8ec983
https://doi.org/10.1021/jm00207a020
https://doi.org/10.1021/jm00207a020
Publikováno v:
Chemischer Informationsdienst. 10
2-Amino-4-aryl-3H-1,5-benzodiazepines were prepared and evaluated for potential neuroleptic activity. Compound 60 showed some activity in the four assays; however, the activity was not consistently observed among other members of the series. The data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96131c86bb4e96f4175dc1b04d0c6592
https://doi.org/10.1002/chin.197910259
https://doi.org/10.1002/chin.197910259
Publikováno v:
Journal of medicinal chemistry. 21(4)
The title compounds (most notably 2a) were synthesized on the basis of the N-methylation hypothesis of schizophrenia. They were evaluated in dopamine and haloperidol receptor assays. The binding characteristics were comparable in some cases to known
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71fe4ad066dc2b85f40d8a0b5d096b9c
https://pubmed.ncbi.nlm.nih.gov/25967
https://pubmed.ncbi.nlm.nih.gov/25967
Publikováno v:
Chemischer Informationsdienst. 9
Some dihydro- and hexahydro-2-dialkylaminoalkyl-9-phenyl-1H-indeno[2,1-c]pyridines were prepared and found to possess significant antiarrhythmic activity. Hydrogenation of the dihydro compounds 4 produced the allcis-hexahydro isomers 5 which were con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c7f6cfc127ec444e09871198042dd4f
https://doi.org/10.1002/chin.197835258
https://doi.org/10.1002/chin.197835258
Publikováno v:
Journal of medicinal chemistry. 25(12)
Several short-acting beta-adrenergic receptor blocking agents have been prepared by incorporating ester functions into the aryl portion of certain (aryloxy)propanolamine systems. In particular, methyl 3-[4-[2-hydroxy-3-(isopropylamino)propoxy]phenyl]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12b41207e70a09b9eb987e8390aa186f
https://pubmed.ncbi.nlm.nih.gov/6130154
https://pubmed.ncbi.nlm.nih.gov/6130154