Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Chi Kin Ip"'
Autor:
Chenxu Yan, Tianshu Zeng, Kailun Lee, Max Nobis, Kim Loh, Luoning Gou, Zefeng Xia, Zhongmin Gao, Mohammed Bensellam, Will Hughes, Jackie Lau, Lei Zhang, Chi Kin Ip, Ronaldo Enriquez, Hanyu Gao, Qiao-Ping Wang, Qi Wu, Jody J. Haigh, D. Ross Laybutt, Paul Timpson, Herbert Herzog, Yan-Chuan Shi
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Neuropeptide Y signalling in the periphery contributes to the regulation of metabolic and energy homeostasis. Here the authors show that blocking Y1R signalling in peripheral tissues using the selective antagonist BIBO3304 ameliorates diet-induced ob
Externí odkaz:
https://doaj.org/article/2c59ad7667ab430db0c8a9a63837c517
Publikováno v:
Molecular Metabolism, Vol 59, Iss , Pp 101455- (2022)
Objective: Aguti-related protein (AGRP) neurons in the arcuate nucleus of the hypothalamus (ARC), which co-express neuropeptide Y (NPY), are key regulators of feeding and energy homeostasis. However, the precise role NPY has within these neurons and
Externí odkaz:
https://doaj.org/article/a41d88dd87914f0eb24d5e3e9010718e
Autor:
Chi Kin Ip
Publikováno v:
STAR Protocols, Vol 2, Iss 2, Pp 100448- (2021)
Summary: Chronic stress has adverse consequences on many organ systems and physiological processes. However, existing protocols show large variability in response and are not suitable for female mice. Here, we provide a step-by-step protocol for esta
Externí odkaz:
https://doaj.org/article/87608332ec0e471a8d24289d54298f37
Autor:
Lei Zhang, Chi Kin Ip, I-Chieh J. Lee, Yue Qi, Felicia Reed, Tim Karl, Jac Kee Low, Ronaldo F. Enriquez, Nicola J. Lee, Paul A. Baldock, Herbert Herzog
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-19 (2018)
Excess caloric intake leads to increased thermogenesis in brown adipose tissue, to limit weight gain. Here, the authors show that neuropeptide FF receptor-2 signalling promotes thermogenesis via control of NPY expression in the arcuate nucleus, and t
Externí odkaz:
https://doaj.org/article/b4414e5490bc452aa201c298f2a70439
Autor:
Kim Loh, Yan-Chuan Shi, Stacey Walters, Mohammed Bensellam, Kailun Lee, Katsuya Dezaki, Masanori Nakata, Chi Kin Ip, Jeng Yie Chan, Esteban N. Gurzov, Helen E. Thomas, Michaela Waibel, James Cantley, Thomas W. Kay, Toshihiko Yada, D. Ross Laybutt, Shane T. Grey, Herbert Herzog
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Islet transplantation is considered one of the potential treatments for T1DM but limited islet survival and their impaired function pose limitations to this approach. Here Loh et al. show that the Y1 receptor is expressed in β- cells and inhibition
Externí odkaz:
https://doaj.org/article/99ec06e40ce64866b58ef492f2dc58bd
Autor:
Aitak Farzi, Jackie Lau, Chi Kin Ip, Yue Qi, Yan-Chuan Shi, Lei Zhang, Ramon Tasan, Günther Sperk, Herbert Herzog
Publikováno v:
eLife, Vol 7 (2018)
Cocaine- and amphetamine-regulated transcript (CART) is widely expressed in the hypothalamus and an important regulator of energy homeostasis; however, the specific contributions of different CART neuronal populations to this process are not known. H
Externí odkaz:
https://doaj.org/article/31b24682ffc842a5bc26f6e2cd4f95b5
Publikováno v:
Cell Metabolism.
Autor:
Shubo Jin, Erin J. Campbell, Chi Kin Ip, Sharon Layfield, Ross A. D. Bathgate, Herbert Herzog, Andrew J. Lawrence
Publikováno v:
Neurochemical Research.
Autor:
Chi Kin Ip, Jemma Rezitis, Lei Zhang, Yue Qi, Nikita Bajaj, Julia Koller, Aitak Farzi, Yan-Chuan Shi, Ramon Tasan, Herbert Herzog
Publikováno v:
SSRN Electronic Journal.
Autor:
Chi Kin Ip, Natalie K.Y. Wee, Ronaldo F. Enriquez, Paul A. Baldock, Nicola J. Lee, Herbert Herzog, Yue Qi, Ireni Clarke
Publikováno v:
International Journal of Obesity. 44:2149-2164
Maintaining energy balance is important to ensure a healthy organism. However, energy partitioning, coordinating the distribution of sufficient energy to different organs and tissues is equally important, but the control of this process is largely un