Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Chi Hu Park"'
Autor:
Ga Ram Jeong, Eun-Hae Jang, Jae Ryul Bae, Soyoung Jun, Ho Chul Kang, Chi-Hu Park, Joo-Ho Shin, Yukio Yamamoto, Keiko Tanaka-Yamamoto, Valina L. Dawson, Ted M. Dawson, Eun-Mi Hur, Byoung Dae Lee
Publikováno v:
Molecular Neurodegeneration, Vol 13, Iss 1, Pp 1-17 (2018)
Abstract Background Mutations in leucine-rich repeat kinase 2 (LRRK2) are the most common cause of familial and sporadic Parkinson’s disease (PD). Elevated kinase activity is associated with LRRK2 toxicity, but the substrates that mediate neurodege
Externí odkaz:
https://doaj.org/article/82ef80fe0e5944a3bd82d33b19606f98
Autor:
Ji-Yeong Lee, Hanna Kim, Areum Jo, Rin Khang, Chi-Hu Park, Soo-Jeong Park, Eunsang Kwag, Joo-Ho Shin
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 10, p 5392 (2021)
α-Synuclein (α-syn) is a hallmark amyloidogenic protein component of Lewy bodies in dopaminergic neurons affected by Parkinson’s disease (PD). Despite the multi-faceted gene regulation of α-syn in the nucleus, the mechanism underlying α-syn cro
Externí odkaz:
https://doaj.org/article/e7fd9a3b3a234b5492506433638c27fa
Antioxidant and anti-aging potential of a peptide formulation (Gal2–Pep) conjugated with gallic acid
Autor:
Hyoung-Shik Kim, Cheolwoo Oh, Yun Suk Huh, Kwanwoo Kim, Hoomin Lee, Sheik Aliya, Vivek K. Bajpai, Chi-Hu Park
Publikováno v:
RSC Advances. 11:29407-29415
Skin is highly vulnerable to premature aging due to external stress, therefore, in this study, a peptide formulation, (galloyl)2–KTPPTTP (Gal2–Pep) was synthesized by combining TPPTTP peptide, and gallic acid (GA). All peptides were synthesized o
Autor:
Joo-Ho Shin, Ji-Yeong Lee, Areum Jo, Soojeong Park, Eunsang Kwag, Rin Khang, Hanna Kim, Chi-Hu Park
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 10
International Journal of Molecular Sciences, Vol 22, Iss 5392, p 5392 (2021)
Volume 22
Issue 10
International Journal of Molecular Sciences, Vol 22, Iss 5392, p 5392 (2021)
α-Synuclein (α-syn) is a hallmark amyloidogenic protein component of Lewy bodies in dopaminergic neurons affected by Parkinson’s disease (PD). Despite the multi-faceted gene regulation of α-syn in the nucleus, the mechanism underlying α-syn cro
Autor:
Hoomin, Lee, Kwanwoo, Kim, Cheolwoo, Oh, Chi-Hu, Park, Sheik, Aliya, Hyoung-Shik, Kim, Vivek K, Bajpai, Yun Suk, Huh
Publikováno v:
RSC advances. 11(47)
Skin is highly vulnerable to premature aging due to external stress, therefore, in this study, a peptide formulation, (galloyl)
Publikováno v:
Journal of Clinical Medicine
Journal of Clinical Medicine, Vol 9, Iss 1, p 52 (2019)
Volume 9
Issue 1
Journal of Clinical Medicine, Vol 9, Iss 1, p 52 (2019)
Volume 9
Issue 1
The inactivation of parkin by mutation or post-translational modification contributes to dopaminergic neuronal death in Parkinson&rsquo
s disease (PD). The substrates of parkin, FBP1 and AIMP2, are accumulated in the postmortem brains of PD pati
s disease (PD). The substrates of parkin, FBP1 and AIMP2, are accumulated in the postmortem brains of PD pati
Autor:
Byoung Dae Lee, Joo Ho Shin, Ted M. Dawson, Ho Chul Kang, Eun Hae Jang, Keiko Tanaka-Yamamoto, Chi Hu Park, Valina L. Dawson, Soyoung Jun, Eun Mi Hur, Ga Ram Jeong, Jae Ryul Bae, Yukio Yamamoto
Publikováno v:
Molecular Neurodegeneration, Vol 13, Iss 1, Pp 1-17 (2018)
Molecular Neurodegeneration
Molecular Neurodegeneration
Background Mutations in leucine-rich repeat kinase 2 (LRRK2) are the most common cause of familial and sporadic Parkinson’s disease (PD). Elevated kinase activity is associated with LRRK2 toxicity, but the substrates that mediate neurodegeneration
Autor:
Sangwoo Ham, Rin Khang, Sun Ha Paek, Byoung Dae Lee, Yun-Song Lee, Jeong-Yun Choi, Ga Ram Jeong, Minkyung Jo, Jeong-kon Seo, Joo Ho Shin, Areum Jo, Yunjong Lee, Yun Il Lee, Hyo Jung Kim, Hyein Kim, Chi Hu Park, Hojin Kang
Publikováno v:
Oncotarget
// Hojin Kang 1,2,* , Rin Khang 1,2,* , Sangwoo Ham 1,* , Ga Ram Jeong 3 , Hyojung Kim 1 , Minkyung Jo 1 , Byoung Dae Lee 3 , Yun Il Lee 4 , Areum Jo 1,2 , ChiHu Park 5,6 , Hyein Kim 1,5 , Jeongkon Seo 7 , Sun Ha Paek 8 , Yun-Song Lee 1 , Jeong-Yun C
Autor:
Tae In Kam, Areum Jo, Sungtaek Oh, Yunjong Lee, Sung Ung Kang, Shaida A. Andrabi, Byoung Dae Lee, Ho Chul Kang, Haisong Jiang, Hojin Kang, Lino Tessarollo, Chan Hyun Na, Yun Il Lee, Senthilkumar S. Karuppagounder, Deborah A. Swing, Manoj Kumar, George K.E. Umanah, Xiaobo Mao, Chi Hu Park, Ted M. Dawson, Jin Whan Cho, Hyo Jung Kim, Sangwoo Ham, Han Seok Ko, Hyein Kim, Ji-Yeong Lee, Sheila K. Pirooznia, Joo Ho Shin, Valina L. Dawson, Shih Ching Chou, Hanna Kim, Sun Ha Paek, Stewart Neifert, Hyejin Park, Rin Khang
Publikováno v:
Sci Transl Med
Accumulation of the parkin-interacting substrate (PARIS; ZNF746), due to inactivation of parkin, contributes to Parkinson's disease (PD) through repression of peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α; PPARGC1A) activity.
Autor:
Sang Hyun Moh, Young-Seung Yoon, Miyoung Ha, Junsung Kim, Bum Ho Yoo, Chi-Hu Park, Yoon-Ju Jung
Publikováno v:
Journal of Food Chemistry & Nanotechnology.