Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Chi Hang Tse"'
Autor:
Chi-Hang Tse, Huapeng Lin, Vincent Wai-Sun Wong, Jimmy Che-To Lai, Terry Cheuk-Fung Yip, Howard H.W. Leung, Angel Mei-Ling Chim, Grace Lai-Hung Wong, Anthony W.H. Chan, Sally She-Ting Shu, Carl Whatling
Publikováno v:
Liver international : official journal of the International Association for the Study of the LiverREFERENCES. 42(1)
BACKGROUND & AIMS How adiposity influences the effect of genetic variants on non-alcoholic fatty liver disease (NAFLD) in the Asian population remains unclear. We aimed to study the association between genetic risk variants and susceptibility/severit
Publikováno v:
Journal of Chemical Theory and Computation. 15:2913-2924
Determination of membrane permeability to small molecules from first-principles represents a promising approach for screening lead compounds according to their permeation properties upstream in the drug discovery process and prior to their synthesis.
Autor:
Vincent Wai-Sun Wong, Chi-Hang Tse, Tommy Tsan-Yuk Lam, Grace Lai-Hung Wong, Angel Mei-Ling Chim, Winnie Chiu-Wing Chu, David Ka-Wai Yeung, Patrick Tik-Wan Law, Hoi-Shan Kwan, Jun Yu, Joseph Jao-Yiu Sung, Henry Lik-Yuen Chan
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e62885 (2013)
The human gut microbiota has profound influence on host metabolism and immunity. This study characterized the fecal microbiota in patients with nonalcoholic steatohepatitis (NASH). The relationship between microbiota changes and changes in hepatic st
Externí odkaz:
https://doaj.org/article/13328975a72b47a287651a1e7ca37c7e
Publikováno v:
Journal of Chemical Theory and Computation. 14:2895-2909
Prediction of membrane permeability to small molecules represents an important aspect of drug discovery. First-principles calculations of this quantity require an accurate description of both the thermodynamics and kinetics that underlie translocatio
Autor:
J. Pang, W. Xu, P. C.-L. Choi, V. W.-S. Wong, Xiang Zhang, Grace Lai-Hung Wong, Anthony W.H. Chan, Hung Chan, Jun Yu, Sally She-Ting Shu, Hoi-Yun Chan, Chi-Hang Tse
Publikováno v:
Alimentary Pharmacology & Therapeutics. 46:175-182
Background Patients with nonalcoholic steatohepatitis (NASH) have gut dysbiosis and intestinal bacterial overgrowth. Aim To test the hypothesis that endotoxemia is associated with the histological severity of nonalcoholic fatty liver disease (NAFLD)
Autor:
Vincent Wai-Sun Wong, Paul Cheung-Lung Choi, Sharon Hoi-Ying Lau, Anthony W.H. Chan, Jackie Siu-Woon Cheng, Elbert Kam-Yeung Lee, Polly Oi-Ying Chan, Grace Lai-Hung Wong, Justin Ming-Yin Ma, Henry Lik-Yuen Chan, Chi-Hang Tse, Joe Cho-Yiu Cheng
Publikováno v:
Journal of Gastroenterology and Hepatology. 30:1040-1048
Background/Aims Interleukin-28B (IL28B) and patatin-like phospholipase domain containing 3 (PNPLA3) gene polymorphisms are associated with hepatitis C virus (HCV) clearance and fatty liver, respectively. We aimed to test if their polymorphisms are as
Autor:
Vivian Chi-Yee Chung, Zhuo Yu, Angel Mei-Ling Chim, Grace Lai-Hung Wong, Hoi-Yun Chan, Zhan Cham-Yan Chan, Chi-Hang Tse, Henry Lik-Yuen Chan, Tina Kit-Ting Lau, Catherine Ka-Yan Wong, Calvin Leung, Yee-Kit Tse, Candace Yim Chan, Vincent Wai-Sun Wong, Patricia Po-Lai Ho
Publikováno v:
Journal of Gastroenterology and Hepatology. 30:582-590
Background and Aims The prognostic role of noninvasive assessments of liver fibrosis has been evolving. Our aim was to investigate the prognostic value of liver stiffness measurement (LSM) with transient elastography and serum-based Hui index to pred
Autor:
P. C.-L. Choi, V. W.-S. Wong, Anthony W.H. Chan, Chi-Hang Tse, Grace Lai-Hung Wong, Zhuo Yu, Angel Mei-Ling Chim, Hung Chan, Hoi-Yun Chan
Publikováno v:
Alimentary Pharmacology & Therapeutics. 39:883-893
Summary Background Metabolic syndrome is a known risk factor of cirrhosis in chronic hepatitis B (CHB). Aim To investigate the effects of coincidental metabolic syndrome on liver fibrosis progression in treatment-naive CHB patients. Methods A total o
Autor:
Chi-Hang Tse, Zhuo Yu, Hoi-Yun Chan, Vincent Wai-Sun Wong, Grace Lai-Hung Wong, Henry Lik-Yuen Chan
Publikováno v:
Journal of Gastroenterology and Hepatology. 28:1842-1848
Background and Aims The European Association for the Study of the Liver (EASL) defines the inactive hepatitis B virus (HBV) carrier state based on HBV DNA and alanine aminotransferase (ALT) levels. This study aimed to evaluate the risk of disease pro
Autor:
Chi-Hang Tse, Vincent Wai-Sun Wong, Henry Lik-Yuen Chan, Angeline Oi-Shan Lo, Grace Lai-Hung Wong, Hoi-Yun Chan, Angel Mei-Ling Chim
Publikováno v:
Antiviral Therapy. 18:979-986
Background Kinetics of serum hepatitis B surface antigen (HBsAg) level in hepatitis B e antigen (HBeAg)-negative chronic hepatitis B patients presented with severe reactivation and received oral antiviral therapy is unknown. We aimed to investigate t