Zobrazeno 1 - 10 of 129 pro vyhledávání: '"Chi Bin Chien"'
1
Akademický článek
Efficient targeted integration directed by short homology in zebrafish and mammalian cells
Autor: Wesley A Wierson, Jordan M Welker, Maira P Almeida, Carla M Mann, Dennis A Webster, Melanie E Torrie, Trevor J Weiss, Sekhar Kambakam, Macy K Vollbrecht, Merrina Lan, Kenna C McKeighan, Jacklyn Levey, Zhitao Ming, Alec Wehmeier, Christopher S Mikelson, Jeffrey A Haltom, Kristen M Kwan, Chi-Bin Chien, Darius Balciunas, Stephen C Ekker, Karl J Clark, Beau R Webber, Branden S Moriarity, Stacy L Solin, Daniel F Carlson, Drena L Dobbs, Maura McGrail, Jeffrey Essner
Publikováno v: eLife, Vol 9 (2020)
Efficient precision genome engineering requires high frequency and specificity of integration at the genomic target site. Here, we describe a set of resources to streamline reporter gene knock-ins in zebrafish and demonstrate the broader utility of t
Externí odkaz: https://doaj.org/article/753d782fc25e478bab0a05b01b9d9f77
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2
Shutdown corner, a large deletion mutant isolated from a haploid mutagenesis screen in zebrafish
Autor: Macaulie A Casey, Jonathon T Hill, Kazuyuki Hoshijima, Chase D Bryan, Suzanna L Gribble, J Thomas Brown, Chi-Bin Chien, H Joseph Yost, Kristen M Kwan
Publikováno v: G3 Genes|Genomes|Genetics. 12
Morphogenesis, the formation of three-dimensional organ structures, requires precise coupling of genetic regulation and complex cell behaviors. The genetic networks governing many morphogenetic systems, including that of the embryonic eye, are poorly
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::450b7401f5cf8f29efec28ff41893287
https://doi.org/10.1093/g3journal/jkab442
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3
Akademický článek
The RNA Binding Protein Igf2bp1 Is Required for Zebrafish RGC Axon Outgrowth In Vivo.
Autor: John A Gaynes, Hideo Otsuna, Douglas S Campbell, John P Manfredi, Edward M Levine, Chi-Bin Chien
Publikováno v: PLoS ONE, Vol 10, Iss 9, p e0134751 (2015)
Attractive growth cone turning requires Igf2bp1-dependent local translation of β-actin mRNA in response to external cues in vitro. While in vivo studies have shown that Igf2bp1 is required for cell migration and axon terminal branching, a requiremen
Externí odkaz: https://doaj.org/article/700c42b15c8847ec81f0ab4dda195363
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4
Akademický článek
Small molecule suppressors of Drosophila kinesin deficiency rescue motor axon development in a zebrafish model of spinal muscular atrophy.
Autor: Andrew Gassman, Le T Hao, Leena Bhoite, Chad L Bradford, Chi-Bin Chien, Christine E Beattie, John P Manfredi
Publikováno v: PLoS ONE, Vol 8, Iss 9, p e74325 (2013)
Proximal spinal muscular atrophy (SMA) is the most common inherited motor neuropathy and the leading hereditary cause of infant mortality. Currently there is no effective treatment for the disease, reflecting a need for pharmacologic interventions th
Externí odkaz: https://doaj.org/article/f2dc9b0fc7754f7dbb55418140232e0b
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6
Efficient targeted integration directed by short homology in zebrafish and mammalian cells
Autor: Jacklyn Levey, Merrina Lan, Carla M. Mann, Maura McGrail, Maira P. Almeida, Beau R. Webber, Kristen M. Kwan, Dennis A. Webster, Trevor J. Weiss, Jeffrey J. Essner, Darius Balciunas, Wesley A. Wierson, Karl J. Clark, Zhitao Ming, Jeffrey A. Haltom, Alec Wehmeier, Stephen C. Ekker, Melanie E. Torrie, Christopher S. Mikelson, Stacy L. Solin, Sekhar Kambakam, Daniel F. Carlson, Macy K. Vollbrecht, Branden S. Moriarity, Jordan M. Welker, Chi Bin Chien, Drena Dobbs, Kenna C. McKeighan
Publikováno v: eLife, Cambridge : eLife Sciences Publications, Ltd, 2020, vol. 9, art. no. e53968, p. [1-25]
eLife, Vol 9 (2020)
eLife
Efficient precision genome engineering requires high frequency and specificity of integration at the genomic target site. Here, we describe a set of resources to streamline reporter gene knock-ins in zebrafish and demonstrate the broader utility of t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfdaa4c2ba4444b21a6e2fac41b3b74c
https://repository.vu.lt/VU:ELABAPDB141054958&prefLang=en_US
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7
Akademický článek
Zebrafish foxP2 zinc finger nuclease mutant has normal axon pathfinding.
Autor: Lingyan Xing, Kazuyuki Hoshijima, David J Grunwald, Esther Fujimoto, Tyler S Quist, Jacob Sneddon, Chi-Bin Chien, Tamara J Stevenson, Joshua L Bonkowsky
Publikováno v: PLoS ONE, Vol 7, Iss 8, p e43968 (2012)
foxP2, a forkhead-domain transcription factor, is critical for speech and language development in humans, but its role in the establishment of CNS connectivity is unclear. While in vitro studies have identified axon guidance molecules as targets of f
Externí odkaz: https://doaj.org/article/964cfcf30ec847a9a096a24311793c0b
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8
Akademický článek
Regulation of zebrafish skeletogenesis by ext2/dackel and papst1/pinscher.
Autor: Aurélie Clément, Malgorzata Wiweger, Sophia von der Hardt, Melissa A Rusch, Scott B Selleck, Chi-Bin Chien, Henry H Roehl
Publikováno v: PLoS Genetics, Vol 4, Iss 7, p e1000136 (2008)
Mutations in human Exostosin genes (EXTs) confer a disease called Hereditary Multiple Exostoses (HME) that affects 1 in 50,000 among the general population. Patients with HME have a short stature and develop osteochondromas during childhood. Here we
Externí odkaz: https://doaj.org/article/b06bc09025b8402dade8eb2046f5791d
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9
Akademický článek
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