Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Chhatra B, Kunwar"'
Autor:
Deanna A. Hagge, Pawan Parajuli, Chhatra B. Kunwar, Divya R.S.J.B. Rana, Ruby Thapa, Kapil D. Neupane, Peter Nicholls, Linda B. Adams, Annemieke Geluk, Mahesh Shah, Indra B. Napit
Publikováno v:
EBioMedicine, Vol 23, Iss C, Pp 119-124 (2017)
Background: >94% of new annual leprosy cases are diagnosed in populations co-endemic for soil-transmitted helminths (STH). STH can profoundly dysregulate host immune responses towards Th2 bias, which can be restored over time after deworming. We hypo
Externí odkaz:
https://doaj.org/article/e9ea3e576076414884ba4d8fe8ce4a8e
Autor:
Oleg. A. Mayboroda, Anouk van Hooij, Rico Derks, Susan J.F. van den Eeden, Karin Dijkman, Saraswoti Khadge, Pratibha Thapa, Chhatra B. Kunwar, Deanna A. Hagge, Annemieke Geluk
Publikováno v:
International Journal of Infectious Diseases, Vol 45, Iss C, Pp 46-52 (2016)
Background: Leprosy is an infectious disease caused by Mycobacterium leprae that affects the skin and nerves. Although curable with multidrug therapy, leprosy is complicated by acute inflammatory episodes called reactions, which are the major causes
Externí odkaz:
https://doaj.org/article/aa8df4aad8a548ad96b84f7b10b6eb1d
Publikováno v:
Microbiology. 166:1149-1159
Colonization of the gastrointestinal tract by enterohaemorrhagic Escherichia coli (EHEC) is critically dependent on its ability to sense and respond to various microenvironments within the host. EHEC exposure to physiologically relevant levels of bil
Autor:
Kidist Bobosha, Sheila Tuyet Tang, Jolien J van der Ploeg-van Schip, Yonas Bekele, Marcia VSB Martins, Ole Lund, Kees LMC Franken, Saraswoti Khadge, Maria Araci de Andrade Pontes, Heitor de Sá Gonçalves, Jemal Hussien, Pratibha Thapa, Chhatra B Kunwar, Deanna A Hagge, Abraham Aseffa, Maria Cristina Vidal Pessolani, Geraldo MB Pereira, Tom HM Ottenhoff, Annemieke Geluk
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 107, Iss suppl 1, Pp 112-123 (2012)
Silent transmission of Mycobacterium leprae, as evidenced by stable leprosy incidence rates in various countries, remains a health challenge despite the implementation of multidrug therapy worldwide. Therefore, the development of tools for the early
Externí odkaz:
https://doaj.org/article/b53d11942e994929a326e6a2876411c4
Autor:
Becky L Rivoire, Nathan A Groathouse, Stephen TerLouw, Kapil Dev Neupane, Chaman Ranjit, Bishwa Raj Sapkota, Saraswoti Khadge, Chhatra B Kunwar, Murdo Macdonald, Rachel Hawksworth, Min B Thapa, Deanna A Hagge, Melinda Tibbals, Carol Smith, Tina Dube, Dewei She, Mark Wolff, Eric Zhou, Mamodikoe Makhene, Robin Mason, Christine Sizemore, Patrick J Brennan
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 5, p e2811 (2014)
New tools are required for the diagnosis of pre-symptomatic leprosy towards further reduction of disease burden and its associated reactions. To address this need, two new skin test antigens were developed to assess safety and efficacy in human trial
Externí odkaz:
https://doaj.org/article/7e1eeddeb5ad4ae4898d8b0c85f7af5a
Autor:
William R Berrington, Chhatra B Kunwar, Kapil Neupane, Susan J F van den Eeden, James C Vary, Glenna J Peterson, Richard D Wells, Annemieke Geluk, Deanna A Hagge, Thomas R Hawn
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 11, p e3263 (2014)
Leprosy is characterized by polar clinical, histologic and immunological presentations. Previous immunologic studies of leprosy polarity were limited by the repertoire of cytokines known at the time.We used a candidate gene approach to measure mRNA l
Externí odkaz:
https://doaj.org/article/be1cf818663941d9b10e0fba1a8e454f
Publikováno v:
Microbiology (Reading, England). 166(12)
Colonization of the gastrointestinal tract by enterohaemorrhagic
Autor:
Annemieke Geluk, Indra B. Napit, Peter Nicholls, Linda B. Adams, Kapil D. Neupane, Deanna A. Hagge, Pawan Parajuli, Divya Rsjb Rana, Mahesh Shah, Chhatra B. Kunwar, Ruby Thapa
Publikováno v:
EBioMedicine, 23, 119-124
EBioMedicine
EBioMedicine, Vol 23, Iss C, Pp 119-124 (2017)
EBioMedicine
EBioMedicine, Vol 23, Iss C, Pp 119-124 (2017)
Background > 94% of new annual leprosy cases are diagnosed in populations co-endemic for soil-transmitted helminths (STH). STH can profoundly dysregulate host immune responses towards Th2 bias, which can be restored over time after deworming. We hypo
Autor:
Sayera Banu, Jolien J. van der Ploeg-van Schip, Yonas Bekele, Robert L. Modlin, Abraham Aseffa, Mariëlle C. Haks, Saraswoti Khadge, Annemieke Geluk, Pratibha Thapa, Chhatra B. Kunwar, Maria Tió-Coma, Milton Ozório Moraes, Jelle J. Goeman, Erik W. van Zwet, Isabela Maria Bernardes Goulart, Rosane M. B. Teles, Kidist Bobosha, Roberta Olmo Pinheiro, Deanna A. Hagge, Anouk van Hooij, Tom H. M. Ottenhoff
Publikováno v:
Scientific Reports, 9
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Early diagnosis of leprosy is challenging, particularly its inflammatory reactions, the major cause of irreversible neuropathy in leprosy. Current diagnostics cannot identify which patients are at risk of developing reactions. This study assessed blo
Autor:
Pratibha Thapa, Annemieke Geluk, Karin Dijkman, Saraswoti Khadge, Chhatra B. Kunwar, Oleg A. Mayboroda, Rico J. E. Derks, Susan J. F. van den Eeden, Deanna A. Hagge, Anouk van Hooij
Publikováno v:
International Journal of Infectious Diseases, Vol 45, Iss C, Pp 46-52 (2016)
Summary Background Leprosy is an infectious disease caused by Mycobacterium leprae that affects the skin and nerves. Although curable with multidrug therapy, leprosy is complicated by acute inflammatory episodes called reactions, which are the major