Výsledky vyhledávání - "Chhaminder Kaur"

Akademický článek

High-Throughput Screening to Identify Inhibitors of Plasmodium falciparum Importin α

Autor: Sujata B. Walunj, Manisha M. Dias, Chhaminder Kaur, Kylie M. Wagstaff, Vishakha Dey, Caroline Hick, Swati Patankar, David A. Jans

Publikováno v: Cells, Vol 11, Iss 7, p 1201 (2022)

The global burden of malaria and toxoplasmosis has been limited by the use of efficacious anti-parasitic agents, however, emerging resistance in Plasmodium species and Toxoplasma gondii threatens disease control worldwide, implying that new agents/th

Externí odkaz: https://doaj.org/article/ccfbb4b2e04f4d22aa8fc6b8fabed32c

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The role of upstream open reading frames in translation regulation in the apicomplexan parasites Plasmodium falciparum and Toxoplasma gondii

Autor: Swati Patankar, Chhaminder Kaur

Publikováno v: Parasitology. 148:1277-1287

During their complex life cycles, the Apicomplexan parasites Plasmodium falciparum and Toxoplasma gondii employ several layers of regulation of their gene expression. One such layer is mediated at the level of translation through upstream open readin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::73c7b3c7b5bfb08c5a8b698158c4879c
https://doi.org/10.1017/s0031182021000937

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Messenger RNAs with large numbers of upstream open reading frames are translated via leaky scanning and reinitiation in the asexual stages of Plasmodium falciparum

Autor: Chhaminder Kaur, Swati Patankar, Mayank Kumar

Publikováno v: Parasitology

The genome of Plasmodium falciparum has one of the most skewed base-pair compositions of any eukaryote, with an AT content of 80–90%. As start and stop codons are AT-rich, the probability of finding upstream open reading frames (uORFs) in messenger

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb8a3d53d272cc6d33b8b67101dbeda6
https://doi.org/10.1017/s0031182020000840

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Messenger RNAs with large numbers of upstream ORFs are translated via leaky scanning and reinitiation in the asexual stages ofPlasmodium falciparum

Autor: Mayank Kumar, Swati Patankar, Chhaminder Kaur

The genome ofPlasmodium falciparumhas one of the most skewed base pair compositions of any eukaryote, with an AT content of 80-90%. As start and stop codons are AT-rich, the probability of finding upstream open reading frames (uORFs) in messenger RNA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ccd998afad1f4d51e77e42e0d4aaa84
https://doi.org/10.1101/823443