Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Chew Li Soh"'
Autor:
Panagiotis Douvaras, Diego F. Buenaventura, Bruce Sun, Ashley Lepack, Elizabeth Baker, Elizabeth Simpson, Mark Ebel, Gregory Lallos, Deven LoSchiavo, Nicholas Stitt, Nathaniel Adams, Conor McAuliffe, Ana Forton-Juarez, Brian Kosmyna, Elizabeth Pereira, Benjamin Burnett, David Dilworth, Stephanie Fisher, Jing Wang, Peter Tonge, Mark Tomishima, Carlos Paladini, Dan Wilkinson, Chew-Li Soh, Maya Srinivas, Christoph Patsch, Stefan Irion
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Mucopolysaccharidoses are inherited metabolic disorders caused by the deficiency in lysosomal enzymes required to break down glycosaminoglycans. Accumulation of glycosaminoglycans leads to progressive, systemic degenerative disease. The cent
Externí odkaz:
https://doaj.org/article/95c91876536349f0849eaac799da3482
Autor:
Marcus Gainer, Assen Roguev, Michelle Hung, Rebecca Cottman, Yin Yin Chong, Russell M Gordley, Mark Tomishima, Monika Avina, Timothy K Lu, Vanessa Johnson, Eren Chu, Joseph Sperling, Brett Kiedaisch, Raghav Kannan, Chandra Verma, Chew-Li Soh, Conor McAuliffe
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/e5f99ced4a4d4c5abf261126cd6fc652
Autor:
Sevim Kahraman, Ercument Dirice, Giorgio Basile, Danielle Diegisser, Jahedul Alam, Bente B. Johansson, Manoj K. Gupta, Jiang Hu, Ling Huang, Chew-Li Soh, Danwei Huangfu, Senthil K. Muthuswamy, Helge Raeder, Anders Molven, Rohit N. Kulkarni
Publikováno v:
Nature Metabolism. 4:76-89
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00a90748897c53ea144f3de6c741aed3
https://doi.org/10.1038/s42255-021-00516-2
https://doi.org/10.1038/s42255-021-00516-2
Autor:
Chew-Li Soh, Antonietta Giudice, Robert A. Jenny, David A. Elliott, Tanya Hatzistavrou, Suzanne J. Micallef, Korosh Kianizad, Natalie Seach, Juan Carlos Zúñiga-Pflücker, Ann P. Chidgey, Alan Trounson, Susan K. Nilsson, David N. Haylock, Richard L. Boyd, Andrew G. Elefanty, Edouard G. Stanley
Publikováno v:
Stem Cell Reports, Vol 2, Iss 6, Pp 925-937 (2014)
Thymic epithelial cells (TECs) play a critical role in T cell maturation and tolerance induction. The generation of TECs from in vitro differentiation of human pluripotent stem cells (PSCs) provides a platform on which to study the mechanisms of this
Externí odkaz:
https://doaj.org/article/3c87a70547394bacac7a41d2420f7152
Autor:
Chew-Li Soh, Anna Mikat, Sara Dutton Sackett, Samantha A. Mitchell, Nicholas Quirini, Jon S. Odorico, Inbal Caspi, Danwei Huangfu
Publikováno v:
Transplantation. 105:S16-S16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::018579ecb33917373e99f7c9b897221d
https://doi.org/10.1097/01.tp.0000804364.20737.4c
https://doi.org/10.1097/01.tp.0000804364.20737.4c
Autor:
Chao Zhang, Weiping Shu, Qiaoran Xi, Joan Massagué, Qing V. Li, Sang Yong Kim, Anna-Katerina Hadjantonakis, Yilong Zou, Jie Su, Danwei Huangfu, Chew-Li Soh, Qiong Wang, Sonja Nowotschin
Publikováno v:
Cell Stem Cell. 20:70-86
In this study, we outline a regulatory network that involves the p53 tumor suppressor family and the Wnt pathway acting together with the TGF-β pathway in mesendodermal differentiation of mouse and human embryonic stem cells. Knockout of all three m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7b6c0baea90c97aa37a388d179763c4
https://doi.org/10.1016/j.stem.2016.10.002
https://doi.org/10.1016/j.stem.2016.10.002
Autor:
Qing V. Li, Qiong Wang, Miguel Crespo, Dapeng Yang, Todd Evans, Gary Dixon, Richard Koche, Friederike Dündar, Paul Zumbo, Miriam Gordillo, Abhijit Shukla, Shuibing Chen, Renhe Luo, Chunlong Xu, Bess P. Rosen, Joan Massagué, Ralph Garippa, Matthew Witkin, Chew Li Soh, Danwei Huangfu, Nipun Verma, Qing Xiang, Michael A. Beer, Doron Betel
Publikováno v:
Nature genetics
Human embryonic stem cells (ESCs) and human induced pluripotent stem cells hold great promise for cell-based therapies and drug discovery. However, homogeneous differentiation remains a major challenge, highlighting the need for understanding develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::595ec43a4e36057eb7153240d37e1277
https://pubmed.ncbi.nlm.nih.gov/31110351
https://pubmed.ncbi.nlm.nih.gov/31110351
Autor:
Zengrong Zhu, Danwei Huangfu, Bess P. Rosen, Chew-Li Soh, Federico Gonzalez, Kihyun Lee, Qing V. Li
Publikováno v:
Cell Stem Cell. 18:755-768
Directed differentiation of human pluripotent stem cells (hPSCs) into somatic counterparts is a valuable tool for studying disease. However, examination of developmental mechanisms in hPSCs remains challenging given complex multi-factorial actions at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5e3272f9050126a234f4b3100af73e3
https://doi.org/10.1016/j.stem.2016.03.015
https://doi.org/10.1016/j.stem.2016.03.015
Publikováno v:
Journal of Visualized Experiments : JoVE
Interrogating gene function in self-renewing or differentiating human pluripotent stem cells (hPSCs) offers a valuable platform towards understanding human development and dissecting disease mechanisms in a dish. To capitalize on this potential appli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bedd1f0332d4ec944c82e0afce58404
https://pubmed.ncbi.nlm.nih.gov/28287608
https://pubmed.ncbi.nlm.nih.gov/28287608
Autor:
Shuibing Chen, Ritu Kumar, Sadaf Amin, Qing V. Li, Zengrong Zhu, Todd Evans, Zhong-Dong Shi, Kihyun Lee, Nipun Verma, Chew-Li Soh, Danwei Huangfu, Dapeng Yang
Human disease phenotypes associated with haploinsufficient gene requirements are often not recapitulated well in animal models. Here, we have investigated the association between human GATA6 haploinsufficiency and a wide range of clinical phenotypes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::809931bf58c74df2de84c18864050096
https://europepmc.org/articles/PMC5419850/
https://europepmc.org/articles/PMC5419850/
