Case 28-2024: A 75-Year-Old Woman with Edema, Arthritis, and Proteinuria.

Autor: Jonas BL; From the Department of Medicine, University of North Carolina School of Medicine at Chapel Hill, and Thurston Arthritis Research Center, Chapel Hill (B.L.J.), and the Department of Medicine, Duke University School of Medicine, Durham (L.G.C.-S.) - all in North Carolina; and the Departments of Radiology (R.B.R.), Medicine (P.W.C.), and Pathology (C.T.-A.), Massachusetts General Hospital, and the Departments of Radiology (R.B.R.), Medicine (P.W.C.), and Pathology (C.T.-A.), Harvard Medical School - both in Boston., Balza Romero R; From the Department of Medicine, University of North Carolina School of Medicine at Chapel Hill, and Thurston Arthritis Research Center, Chapel Hill (B.L.J.), and the Department of Medicine, Duke University School of Medicine, Durham (L.G.C.-S.) - all in North Carolina; and the Departments of Radiology (R.B.R.), Medicine (P.W.C.), and Pathology (C.T.-A.), Massachusetts General Hospital, and the Departments of Radiology (R.B.R.), Medicine (P.W.C.), and Pathology (C.T.-A.), Harvard Medical School - both in Boston., Criscione-Schreiber LG; From the Department of Medicine, University of North Carolina School of Medicine at Chapel Hill, and Thurston Arthritis Research Center, Chapel Hill (B.L.J.), and the Department of Medicine, Duke University School of Medicine, Durham (L.G.C.-S.) - all in North Carolina; and the Departments of Radiology (R.B.R.), Medicine (P.W.C.), and Pathology (C.T.-A.), Massachusetts General Hospital, and the Departments of Radiology (R.B.R.), Medicine (P.W.C.), and Pathology (C.T.-A.), Harvard Medical School - both in Boston., Cheung PW; From the Department of Medicine, University of North Carolina School of Medicine at Chapel Hill, and Thurston Arthritis Research Center, Chapel Hill (B.L.J.), and the Department of Medicine, Duke University School of Medicine, Durham (L.G.C.-S.) - all in North Carolina; and the Departments of Radiology (R.B.R.), Medicine (P.W.C.), and Pathology (C.T.-A.), Massachusetts General Hospital, and the Departments of Radiology (R.B.R.), Medicine (P.W.C.), and Pathology (C.T.-A.), Harvard Medical School - both in Boston., Trivin-Avillach C; From the Department of Medicine, University of North Carolina School of Medicine at Chapel Hill, and Thurston Arthritis Research Center, Chapel Hill (B.L.J.), and the Department of Medicine, Duke University School of Medicine, Durham (L.G.C.-S.) - all in North Carolina; and the Departments of Radiology (R.B.R.), Medicine (P.W.C.), and Pathology (C.T.-A.), Massachusetts General Hospital, and the Departments of Radiology (R.B.R.), Medicine (P.W.C.), and Pathology (C.T.-A.), Harvard Medical School - both in Boston.

Publikováno v: The New England journal of medicine [N Engl J Med] 2024 Sep 12; Vol. 391 (10), pp. 942-953.

Intracellular sites of AQP2 S256 phosphorylation identified using inhibitors of the AQP2 recycling itinerary.

Autor: Cheung PW; Division of Nephrology, Program in Membrane Biology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Boukenna M; Division of Nephrology, Program in Membrane Biology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Babicz RSE; Division of Nephrology, Program in Membrane Biology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Mitra S; Division of Nephrology, Program in Membrane Biology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Kay A; Division of Nephrology, Program in Membrane Biology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Paunescu TC; Division of Nephrology, Program in Membrane Biology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Baylor N; Division of Nephrology, Program in Membrane Biology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Liu CS; Division of Nephrology, Program in Membrane Biology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Nair AV; Division of Nephrology, Program in Membrane Biology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Bouley R; Division of Nephrology, Program in Membrane Biology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Brown D; Division of Nephrology, Program in Membrane Biology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.

Publikováno v: American journal of physiology. Renal physiology [Am J Physiol Renal Physiol] 2023 Feb 01; Vol. 324 (2), pp. F152-F167. Date of Electronic Publication: 2022 Dec 01.

Case 15-2020: A 79-Year-Old Man with Hyponatremia and Involuntary Movements of the Arm and Face.

Autor: Cooper CM; From the Departments of Medicine (C.M.C., P.W.C.) and Neurology (E.B.P., J.J.L.), Massachusetts General Hospital, and the Departments of Medicine (C.M.C., P.W.C.) and Neurology (E.B.P., J.J.L.), Harvard Medical School - both in Boston., Cheung PW; From the Departments of Medicine (C.M.C., P.W.C.) and Neurology (E.B.P., J.J.L.), Massachusetts General Hospital, and the Departments of Medicine (C.M.C., P.W.C.) and Neurology (E.B.P., J.J.L.), Harvard Medical School - both in Boston., Penney EB; From the Departments of Medicine (C.M.C., P.W.C.) and Neurology (E.B.P., J.J.L.), Massachusetts General Hospital, and the Departments of Medicine (C.M.C., P.W.C.) and Neurology (E.B.P., J.J.L.), Harvard Medical School - both in Boston., Linnoila JJ; From the Departments of Medicine (C.M.C., P.W.C.) and Neurology (E.B.P., J.J.L.), Massachusetts General Hospital, and the Departments of Medicine (C.M.C., P.W.C.) and Neurology (E.B.P., J.J.L.), Harvard Medical School - both in Boston.

Publikováno v: The New England journal of medicine [N Engl J Med] 2020 May 14; Vol. 382 (20), pp. 1943-1950.

Targeting the Trafficking of Kidney Water Channels for Therapeutic Benefit.

Autor: Cheung PW; Center for Systems Biology, Program in Membrane Biology, and Division of Nephrology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA; email: Brown.Dennis@mgh.harvard.edu., Bouley R; Center for Systems Biology, Program in Membrane Biology, and Division of Nephrology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA; email: Brown.Dennis@mgh.harvard.edu., Brown D; Center for Systems Biology, Program in Membrane Biology, and Division of Nephrology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA; email: Brown.Dennis@mgh.harvard.edu.

Publikováno v: Annual review of pharmacology and toxicology [Annu Rev Pharmacol Toxicol] 2020 Jan 06; Vol. 60, pp. 175-194. Date of Electronic Publication: 2019 Sep 27.

Protein phosphatase 2C is responsible for VP-induced dephosphorylation of AQP2 serine 261.

Autor: Cheung PW; Center for Systems Biology, Program in Membrane Biology and Division of Nephrology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Ueberdiek L; Center for Systems Biology, Program in Membrane Biology and Division of Nephrology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Day J; Center for Systems Biology, Program in Membrane Biology and Division of Nephrology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Bouley R; Center for Systems Biology, Program in Membrane Biology and Division of Nephrology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts., Brown D; Center for Systems Biology, Program in Membrane Biology and Division of Nephrology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts Brown.Dennis@mgh.harvard.edu.

Publikováno v: American journal of physiology. Renal physiology [Am J Physiol Renal Physiol] 2017 Aug 01; Vol. 313 (2), pp. F404-F413. Date of Electronic Publication: 2017 Apr 05.