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Transplanting Human Neural Stem Cells with ≈50% Reduction of SOX9 Gene Dosage Promotes Tissue Repair and Functional Recovery from Severe Spinal Cord Injury.

Autor: Liu JA; Department of Anaesthesiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.; Department of Neuroscience, Tat Chee Avenue, City University of Hong Kong, Hong Kong, China., Tam KW; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China., Chen YL; Department of Anaesthesiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China., Feng X; Department of Anaesthesiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China., Chan CWL; Department of Neuroscience, Tat Chee Avenue, City University of Hong Kong, Hong Kong, China., Lo ALH; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China., Wu KL; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China., Hui MN; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China., Wu MH; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China., Chan KK; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China., Cheung MPL; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China., Cheung CW; Department of Anaesthesiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China., Shum DK; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China., Chan YS; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China., Cheung M; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.

Publikováno v: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2023 Jul; Vol. 10 (20), pp. e2205804. Date of Electronic Publication: 2023 Jun 09.

Nuclear DLC1 exerts oncogenic function through association with FOXK1 for cooperative activation of MMP9 expression in melanoma.

Autor: Yang X; Shenzhen Institute of Research and Innovation (HKU-SIRI), The University of Hong Kong, Shenzhen, China.; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China., Hu F; Shenzhen Institute of Research and Innovation (HKU-SIRI), The University of Hong Kong, Shenzhen, China.; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China., Liu JA; Department of Anaesthesiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China., Yu S; Cancer Centre, Faculty of Health Sciences, University of Macau, Taipa, Macau, China., Cheung MPL; Shenzhen Institute of Research and Innovation (HKU-SIRI), The University of Hong Kong, Shenzhen, China.; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China., Liu X; Department of Pediatric Surgery, Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China., Ng IO; State Key Laboratory of Liver Research and Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China., Guan XY; Department of Clinical Oncology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China., Wong KKW; Centre for PanorOmic Sciences, Proteomics and Metabolomics Core Facility, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China., Sharma R; Centre for PanorOmic Sciences, Proteomics and Metabolomics Core Facility, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China., Lung HL; Department of Biology, Faculty of Science, Hong Kong Baptist University, Hong Kong, China., Jiao Y; Department of Pathology, The Second Affiliated Hospital of Harbin Medical University, Harbin, China., Lee LTO; Cancer Centre, Faculty of Health Sciences, University of Macau, Taipa, Macau, China.; Centre of Reproduction, Development and Aging, Faculty of Health Sciences, University of Macau, Taipa, Macau, China., Cheung M; Shenzhen Institute of Research and Innovation (HKU-SIRI), The University of Hong Kong, Shenzhen, China. mcheung9@hku.hk.; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China. mcheung9@hku.hk.

Publikováno v: Oncogene [Oncogene] 2020 May; Vol. 39 (20), pp. 4061-4076. Date of Electronic Publication: 2020 Mar 25.