Reduction of myocardial ischaemia-reperfusion injury by inactivating oxidized phospholipids

Autor: Yeang, Calvin, Hasanally, Devin, Que, Xuchu, Hung, Ming-Yow, Stamenkovic, Aleksandra, Chan, David, Chaudhary, Rakesh, Margulets, Victoria, Edel, Andrea L, Hoshijima, Masahiko, Gu, Yusu, Bradford, William, Dalton, Nancy, Miu, Phuong, Cheung, David Yc, Jassal, Davinder S, Pierce, Grant N, Peterson, Kirk L, Kirshenbaum, Lorrie A, Witztum, Joseph L, Tsimikas, Sotirios, Ravandi, Amir

Publikováno v: Cardiovascular research, vol 115, iss 1

Aims:Myocardial ischaemia followed by reperfusion (IR) causes an oxidative burst resulting in cellular dysfunction. Little is known about the impact of oxidative stress on cardiomyocyte lipids and their role in cardiac cell death. Our goal was to ide

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::13480b235938ce222e60b4f6f5452eec
https://escholarship.org/uc/item/2j01w3w3

Reduction of myocardial ischaemia-reperfusion injury by inactivating oxidized phospholipids.

Autor: Yeang C; Division of Cardiovascular Diseases, Sulpizio Cardiovascular Center, Department of Medicine, University of California San Diego, La Jolla, CA, USA., Hasanally D; Institute of Cardiovascular Sciences, St. Boniface Hospital Albrechtsen Research Centre, University of Manitoba, Winnipeg, Manitoba, Canada., Que X; Division of Endocrinology and Metabolism, Department of Medicine, University of California San Diego, La Jolla, CA, USA., Hung MY; Division of Cardiology, Department of Internal Medicine, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan.; Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei City, Taiwan., Stamenkovic A; Institute of Cardiovascular Sciences, St. Boniface Hospital Albrechtsen Research Centre, University of Manitoba, Winnipeg, Manitoba, Canada., Chan D; Institute of Cardiovascular Sciences, St. Boniface Hospital Albrechtsen Research Centre, University of Manitoba, Winnipeg, Manitoba, Canada., Chaudhary R; Institute of Cardiovascular Sciences, St. Boniface Hospital Albrechtsen Research Centre, University of Manitoba, Winnipeg, Manitoba, Canada., Margulets V; Institute of Cardiovascular Sciences, St. Boniface Hospital Albrechtsen Research Centre, University of Manitoba, Winnipeg, Manitoba, Canada., Edel AL; Institute of Cardiovascular Sciences, St. Boniface Hospital Albrechtsen Research Centre, University of Manitoba, Winnipeg, Manitoba, Canada., Hoshijima M; Division of Cardiovascular Diseases, Sulpizio Cardiovascular Center, Department of Medicine, University of California San Diego, La Jolla, CA, USA., Gu Y; Division of Cardiovascular Diseases, Sulpizio Cardiovascular Center, Department of Medicine, University of California San Diego, La Jolla, CA, USA., Bradford W; Division of Cardiovascular Diseases, Sulpizio Cardiovascular Center, Department of Medicine, University of California San Diego, La Jolla, CA, USA., Dalton N; Division of Cardiovascular Diseases, Sulpizio Cardiovascular Center, Department of Medicine, University of California San Diego, La Jolla, CA, USA., Miu P; Division of Cardiovascular Diseases, Sulpizio Cardiovascular Center, Department of Medicine, University of California San Diego, La Jolla, CA, USA., Cheung DY; Institute of Cardiovascular Sciences, St. Boniface Hospital Albrechtsen Research Centre, University of Manitoba, Winnipeg, Manitoba, Canada., Jassal DS; Institute of Cardiovascular Sciences, St. Boniface Hospital Albrechtsen Research Centre, University of Manitoba, Winnipeg, Manitoba, Canada.; Department of Physiology and Pathophysiology, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada., Pierce GN; Institute of Cardiovascular Sciences, St. Boniface Hospital Albrechtsen Research Centre, University of Manitoba, Winnipeg, Manitoba, Canada.; Department of Physiology and Pathophysiology, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada., Peterson KL; Division of Cardiovascular Diseases, Sulpizio Cardiovascular Center, Department of Medicine, University of California San Diego, La Jolla, CA, USA., Kirshenbaum LA; Institute of Cardiovascular Sciences, St. Boniface Hospital Albrechtsen Research Centre, University of Manitoba, Winnipeg, Manitoba, Canada., Witztum JL; Division of Endocrinology and Metabolism, Department of Medicine, University of California San Diego, La Jolla, CA, USA., Tsimikas S; Division of Cardiovascular Diseases, Sulpizio Cardiovascular Center, Department of Medicine, University of California San Diego, La Jolla, CA, USA., Ravandi A; Institute of Cardiovascular Sciences, St. Boniface Hospital Albrechtsen Research Centre, University of Manitoba, Winnipeg, Manitoba, Canada.; Department of Physiology and Pathophysiology, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.

Publikováno v: Cardiovascular research [Cardiovasc Res] 2019 Jan 01; Vol. 115 (1), pp. 179-189.