Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Cheung, BB"'
Autor:
Chen, J, Nelson, C, Wong, M, Tee, AE, Liu, PY, La, T, Fletcher, JI, Kamili, A, Mayoh, C, Bartenhagen, C, Trahair, TN, Xu, N, Jayatilleke, N, Peng, H, Atmadibrata, B, Cheung, BB, Lan, Q, Bryan, TM, Mestdagh, P, Vandesompele, J, Combaret, V, Boeva, V, Wang, JY, Janoueix-Lerosey, I, Cowley, MJ, MacKenzie, KL, Dolnikov, A, Li, J, Polly, P, Marshall, GM, Reddel, RR, Norris, MD, Haber, M, Fischer, M, Zhang, XD, Pickett, HA, Liu, T
PurposeTERT gene rearrangement with transcriptional superenhancers leads to TERT overexpression and neuroblastoma. No targeted therapy is available for clinical trials in patients with TERT-rearranged neuroblastoma.Experimental designAnticancer agent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::e304684dc45deac0e7292e9fe1f60923
https://hdl.handle.net/10453/148374
https://hdl.handle.net/10453/148374
Autor:
Tee, AE, Ciampa, OC, Wong, M, Fletcher, JI, Kamili, A, Chen, J, Ho, N, Sun, Y, Carter, DR, Cheung, BB, Marshall, GM, Liu, PY, Liu, T
Patients with neuroblastoma due to MYCN oncogene amplification and consequent N-Myc oncoprotein overexpression have very poor prognosis. The cyclin-dependent kinase 7 (CDK7)/super-enhancer inhibitor THZ1 suppresses MYCN gene transcription, reduces ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::b75aefb39f03d33a9c833c730d5822d8
https://hdl.handle.net/10453/143977
https://hdl.handle.net/10453/143977
© 2019, The Author(s). Purpose: The tripartite motif (TRIM)16 acts as a tumour suppressor in both squamous cell carcinoma (SCC) and melanoma. TRIM16 is known to be secreted by keratinocytes, but no studies have been reported yet to assess the relati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::ed0b74baa71b6f2aa183057333bdaabf
https://hdl.handle.net/10453/138259
https://hdl.handle.net/10453/138259
Autor:
Ooi, CY, Carter, DR, Liu, B, Mayoh, C, Beckers, A, Lalwani, A, Nagy, Z, De Brouwer, S, Decaesteker, B, Hung, TT, Norris, MD, Haber, M, Liu, T, De Preter, K, Speleman, F, Cheung, BB, Marshall, GM
© 2018 American Association for Cancer Research. Neuroblastoma is a pediatric cancer of the sympathetic nervous system where MYCN amplification is a key indicator of poor prognosis. However, mechanisms by which MYCN promotes neuroblastoma tumorigene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::3e6e8935f80c67c2dc5be9ff6480f4d2
https://hdl.handle.net/10453/133116
https://hdl.handle.net/10453/133116
Autor:
Sutton, SK, Carter, DR, Kim, P, Tan, O, Arndt, GM, Zhang, XD, Baell, J, Noll, BD, Wang, S, Kumar, N, McArthur, GA, Cheung, BB, Marshall, GM
There is an urgent need for better therapeutic options for advanced melanoma patients, particularly those without the BRAFV600E/K mutation. In melanoma cells, loss of TRIM16 expression is a marker of cell migration and metastasis, while the BRAF inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::056173978bd980eb10e8d76f29c82777
https://hdl.handle.net/10453/159919
https://hdl.handle.net/10453/159919
Glutathione biosynthesis is upregulated at the initiation of MYCN-driven neuroblastoma tumorigenesis
Autor:
Carter, DR, Sutton, SK, Pajic, M, Murray, J, Sekyere, EO, Fletcher, J, Beckers, A, De Preter, K, Speleman, F, George, RE, Haber, M, Norris, MD, Cheung, BB, Marshall, GM
The MYCN gene is amplified and overexpressed in a large proportion of high stage neuroblastoma patients and has been identified as a key driver of tumorigenesis. However, the mechanism by which MYCN promotes tumor initiation is poorly understood. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::9f267bbbbb04d3f0e9411f369da78b18
https://hdl.handle.net/10453/159921
https://hdl.handle.net/10453/159921
Akademický článek
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Autor:
Cheung BB; Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, UNSW Sydney, Sydney, Australia. bcheung@ccia.unsw.edu.au.; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, NSW, Australia. bcheung@ccia.unsw.edu.au., Mittra R; Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, UNSW Sydney, Sydney, Australia., Murray J; Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, UNSW Sydney, Sydney, Australia., Wang Q; Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, UNSW Sydney, Sydney, Australia., Seneviratne JA; Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, UNSW Sydney, Sydney, Australia., Raipuria M; Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, UNSW Sydney, Sydney, Australia., Wong IPL; Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, UNSW Sydney, Sydney, Australia., Restuccia D; Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, UNSW Sydney, Sydney, Australia., Gifford A; Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, UNSW Sydney, Sydney, Australia., Salib A; Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, UNSW Sydney, Sydney, Australia., Sutton S; Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, UNSW Sydney, Sydney, Australia., Huang L; Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, UNSW Sydney, Sydney, Australia., Ferdowsi PV; Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, UNSW Sydney, Sydney, Australia., Tsang J; Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, UNSW Sydney, Sydney, Australia., Sekyere E; Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, UNSW Sydney, Sydney, Australia., Mayoh C; Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, UNSW Sydney, Sydney, Australia.; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, NSW, Australia., Luo L; Institute for Molecular Bioscience, University of Queensland, Brisbane, QLD, Australia., Brown DL; Institute for Molecular Bioscience, University of Queensland, Brisbane, QLD, Australia., Stow JL; Institute for Molecular Bioscience, University of Queensland, Brisbane, QLD, Australia., Zhu S; Department of Biochemistry and Molecular Biology, Cancer Center and Center for Individualized Medicine, Mayo Clinic, Rochester, MN, USA., Young RJ; Peter MacCallum Cancer Centre, Melbourne, Australia., Solomon BJ; Peter MacCallum Cancer Centre, Melbourne, Australia., Chappaz S; Anatomy & Developmental Biology, Monash University, Melbourne, Australia., Kile B; Faculty of Health and Medical Sciences at the University of Adelaide, Adelaide, Australia., Kueh A; Blood Cells and Blood Cancer Division, Walter and Eliza Hall Institute, Melbourne, Australia.; Department of Medical Biology, The University of Melbourne, Victoria, 3052, Australia., Herold MJ; Blood Cells and Blood Cancer Division, Walter and Eliza Hall Institute, Melbourne, Australia.; Department of Medical Biology, The University of Melbourne, Victoria, 3052, Australia., Hilton DJ; Blood Cells and Blood Cancer Division, Walter and Eliza Hall Institute, Melbourne, Australia.; Department of Medical Biology, The University of Melbourne, Victoria, 3052, Australia., Liu T; Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, UNSW Sydney, Sydney, Australia.; University of New South Wales Centre for Childhood Cancer Research, Sydney, NSW 2052, Australia., Norris MD; Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, UNSW Sydney, Sydney, Australia.; University of New South Wales Centre for Childhood Cancer Research, Sydney, NSW 2052, Australia., Haber M; Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, UNSW Sydney, Sydney, Australia.; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, NSW, Australia., Carter DR; Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, UNSW Sydney, Sydney, Australia.; School of Biomedical Engineering, University of Technology Sydney, Sydney, Australia., Parker MW; ACRF Facility for Innovative Cancer Drug Discovery and Department of Biochemistry and Pharmacology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria, Australia.; ACRF Rational Drug Discovery Centre, St. Vincent's Institute of Medical Research, Fitzroy, Victoria, Australia., Marshall GM; Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre, UNSW Sydney, Sydney, Australia. glenn.marshall@health.nsw.gov.au.; Kids Cancer Centre, Sydney Children's Hospital, Sydney, 2031, NSW, Australia. glenn.marshall@health.nsw.gov.au.
Publikováno v:
Communications biology [Commun Biol] 2024 Oct 14; Vol. 7 (1), pp. 1322. Date of Electronic Publication: 2024 Oct 14.
Autor:
Hassan N; Cancer and Stem Cell Laboratory, School of Medical Sciences, Faculty of Medicine and Health, University of Sydney, Kolling Institute, Sydney, NSW, Australia., Yi H; Cancer and Stem Cell Laboratory, School of Medical Sciences, Faculty of Medicine and Health, University of Sydney, Kolling Institute, Sydney, NSW, Australia., Malik B; Cancer and Stem Cell Laboratory, School of Medical Sciences, Faculty of Medicine and Health, University of Sydney, Kolling Institute, Sydney, NSW, Australia., Gaspard-Boulinc L; Cancer and Stem Cell Laboratory, School of Medical Sciences, Faculty of Medicine and Health, University of Sydney, Kolling Institute, Sydney, NSW, Australia.; Department of Biology, Ecole Normale Supérieure, PSL University Paris, Paris, France., Samaraweera SE; Acute Leukaemia Laboratory, Centre for Cancer Biology, University of South Australia and SA Pathology, Adelaide, SA, Australia., Casolari DA; Acute Leukaemia Laboratory, Centre for Cancer Biology, University of South Australia and SA Pathology, Adelaide, SA, Australia., Seneviratne J; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia., Balachandran A; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia., Chew T; Sydney Informatics Hub, Core Research Facilities, University of Sydney, Camperdown, NSW, Australia., Duly A; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia., Carter DR; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia., Cheung BB; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia., Norris M; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia., Haber M; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia., Kavallaris M; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia.; Australian Centre for NanoMedicine and ARC Centre of Excellence in Convergent Bio-Nano-Science and Technology, University of New South Wales, Sydney, NSW, Australia., Marshall GM; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia.; Kids Cancer Centre, Sydney Children's Hospital, Randwick, NSW, Australia., Zhang XD; School of Biomedical Sciences and Pharmacy, The University of Newcastle, Callaghan, NSW, Australia.; Translational Research Institute, Henan Provincial People's Hospital and People's Hospital of Zhengzhou University, Academy of Medical Science, Zhengzhou University, Zhengzhou, Henan, China., Liu T; Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia., Wang J; Department of Medicine, Columbia Center for Human Development, Columbia University Irving Medical Center, New York, NY., Liebermann DA; Fels Institute for Cancer Research and Molecular Biology and Department of Medical Genetics and Molecular Biochemistry, School of Medicine, Temple University, Philadelphia, PA., D'Andrea RJ; Acute Leukaemia Laboratory, Centre for Cancer Biology, University of South Australia and SA Pathology, Adelaide, SA, Australia., Wang JY; Cancer and Stem Cell Laboratory, School of Medical Sciences, Faculty of Medicine and Health, University of Sydney, Kolling Institute, Sydney, NSW, Australia.
Publikováno v:
Blood [Blood] 2024 Jul 04; Vol. 144 (1), pp. 84-98.
Autor:
Salib A; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Kensington, NSW, 2052, Australia.; School of Women's and Children's Health, UNSW Sydney, Kensington, NSW, 2052, Australia., Jayatilleke N; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Kensington, NSW, 2052, Australia., Seneviratne JA; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Kensington, NSW, 2052, Australia., Mayoh C; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Kensington, NSW, 2052, Australia.; School of Women's and Children's Health, UNSW Sydney, Kensington, NSW, 2052, Australia., De Preter K; Center for Medical Genetics (CMGG), Ghent University, Medical Research Building (MRB1), Ghent, Belgium., Speleman F; Center for Medical Genetics (CMGG), Ghent University, Medical Research Building (MRB1), Ghent, Belgium., Cheung BB; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Kensington, NSW, 2052, Australia.; School of Women's and Children's Health, UNSW Sydney, Kensington, NSW, 2052, Australia., Carter DR; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Kensington, NSW, 2052, Australia. Daniel.Carter@uts.edu.au.; School of Biomedical Engineering, University of Technology Sydney, Ultimo, NSW, 2007, Australia. Daniel.Carter@uts.edu.au., Marshall GM; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Kensington, NSW, 2052, Australia. glenn.marshall@health.nsw.gov.au.; Kids Cancer Centre, Sydney Children's Hospital, Randwick, NSW, 2031, Australia. glenn.marshall@health.nsw.gov.au.
Publikováno v:
Oncogene [Oncogene] 2024 Jan; Vol. 43 (5), pp. 363-377. Date of Electronic Publication: 2023 Dec 04.