Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Cheul H. Cho"'
Autor:
Yongzhen Liu, Thomas R. Cafiero, Debby Park, Abhishek Biswas, Benjamin Y. Winer, Cheul H. Cho, Yaron Bram, Vasuretha Chandar, Aoife K. O’ Connell, Hans P. Gertje, Nicholas Crossland, Robert E. Schwartz, Alexander Ploss
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Hepatitis B virus (HBV) only infects humans and chimpanzees, posing major challenges for modeling HBV infection and chronic viral hepatitis. The major barrier in establishing HBV infection in non-human primates lies at incompatibilities betw
Externí odkaz:
https://doaj.org/article/715209dd3f1c45be80f29128c56a1eea
Autor:
Nolan B. Skop, Sweta Singh, Henri Antikainen, Chaitali Saqcena, Frances Calderon, Deborah E. Rothbard, Cheul H. Cho, Chirag D. Gandhi, Steven W. Levison, Radek Dobrowolski
Publikováno v:
ASN Neuro, Vol 11 (2019)
There is intense interest and effort toward regenerating the brain after severe injury. Stem cell transplantation after insult to the central nervous system has been regarded as the most promising approach for repair; however, engrafting cells alone
Externí odkaz:
https://doaj.org/article/3fd65c188d424756b45e1f8065792266
Publikováno v:
BioTechniques, Vol 53, Iss 5, Pp 315-318 (2012)
This paper introduces a benchtop method for patterning mammalian cells—i.e., for culturing cells at specific locations—on planar substrates. Compared with standard cell culture techniques, which do not allow the control of what areas of a monolay
Externí odkaz:
https://doaj.org/article/fd6d41c4240a47b3a0d2f9d754e95182
Autor:
Cheul H. Cho, Jaesung Park, Arno W. Tilles, François Berthiaume, Mehmet Toner, Martin L. Yarmush
Publikováno v:
BioTechniques, Vol 48, Iss 1, Pp 47-52 (2010)
Microfabrication and micropatterning techniques in tissue engineering offer great potential for creating and controlling microenvironments in which cell behavior can be observed. Here we present a novel approach to generate layered patterning of hepa
Externí odkaz:
https://doaj.org/article/8966ae347e544cd9a3b35e883637c5b8
Autor:
Yaron Bram, Amit Parekh, Gabriel Lipkowitz, Robert E. Schwartz, Rohit Jindal, Benjamin Y. Winer, Eric Novik, Lance Parsons, Cheul H. Cho, Jenna M. Gaska, Anil B. Shrirao, Alexander Ploss, Robert W. Leach
Publikováno v:
Hepatology
Hepatitis B virus (HBV) remains a major global health problem with 257 million chronically infected individuals worldwide, of whom approximately 20 million are co-infected with hepatitis delta virus (HDV). Progress toward a better understanding of th
Autor:
Eitan Pludwinski, Cheul H. Cho, James S. MacDonald, Amit Parekh, Jacquelyn Dwyer, Zaid Jayyosi, Robert Freedman, Eric Novik, Anil B. Shrirao, James K. Morelli
Publikováno v:
Toxicology and Applied Pharmacology. 336:20-30
The failure of drug candidates during clinical trials and post-marketing withdrawal due to Drug Induced Liver Injury (DILI), results in significant late-stage attrition in the pharmaceutical industry. Animal studies have proven insufficient to defini
Publikováno v:
Journal of Biomedical Materials Research Part A. 105:2119-2128
In this study, a new 3D liver model was developed using biomimetic nanofiber scaffolds and co-culture system consisting of hepatocytes and fibroblasts for the maintenance of long-term liver functions. The chitosan nanofiber scaffolds were fabricated
Autor:
Benjamin Y. Winer, Brigitte Heller, Eitan Pludwinski, Tom W. Muir, Anil B. Shrirao, Tiffany Huang, Felix Wojcik, Cheul H. Cho, Amit Parekh, Gabriel Lipkowitz, Eric Novik, Alexander Ploss
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Hepatitis B virus causes chronic infections in 250 million people worldwide. Chronic hepatitis B virus carriers are at risk of developing fibrosis, cirrhosis, and hepatocellular carcinoma. A prophylactic vaccine exists and currently available antivir
Autor:
Cheul H. Cho, Bonnie Firestein-Miller, Frank H. Kung, Ellen Townes-Anderson, Anil B. Shrirao, Derek Yip
Publikováno v:
Journal of visualized experiments : JoVE. (120)
Substrate and cell patterning techniques are widely used in cell biology to study cell-to-cell and cell-to-substrate interactions. Conventional patterning techniques work well only with simple shapes, small areas and selected bio-materials. This arti
Publikováno v:
Journal of biomedical materials research. Part A. 105(8)
In this study, a new 3D liver model was developed using biomimetic nanofiber scaffolds and co-culture system consisting of hepatocytes and fibroblasts for the maintenance of long-term liver functions. The chitosan nanofiber scaffolds were fabricated