Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Cheuk S, Kwok"'
Autor:
Stephen J. Forman, Firoozeh Sahebi, Neil Kogut, Jasmine Zain, Peter Falk, Arturo Molina, Andrew Dagis, Vinod Pullarkat, Ricardo Spielberger, Amrita Krishnan, Cheuk S. Kwok, David D. Smith, Auayporn Nademanee, Roberto Rodriguez, Anne-Line Anderson, Leslie Popplewell, David S. Snyder, Margaret R. O'Donnell, Mark Kirschbaum, Ryotaro Nakamura, Andrew Raubitschek, Pablo Parker, Dave Yamauchi, Christine White, Anthony S. Stein, Eileen P. Smith, Henry C. Fung
Publikováno v:
Blood. 106:2896-2902
We conducted a phase 1/2 trial of high-dose 90Y-ibritumomab tiuxetan in combination with high-dose etoposide (VP-16) 40 to 60 mg/kg (day -4) and cyclophosphamide 100 mg/kg (day -2) followed by autologous stem cell transplantation (ASCT) in 31 patient
Autor:
David Colcher, An Liu, Jeffrey Y.C. Wong, John E. Shively, Anna M. Wu, Paul J. Yazaki, David Ikle, David Chu, Dave Yamauchi, Sharon P. Wilczynski, Lawrence E. Williams, Andrew Raubitschek, Cheuk S. Kwok
Publikováno v:
Clinical Cancer Research. 10:5014-5021
Purpose: The chimeric T84.66 (cT84.66) minibody is a novel engineered antibody construct (VL-linker-VH-CH3; 80 kDa) that demonstrates bivalent and high affinity (4 × 1010 m−1) binding to carcinoembryonic antigen (CEA). The variable regions (VL and
Publikováno v:
Cancer biotherapyradiopharmaceuticals. 29(2)
Time-activity uptake curves [u(t) in % injected dose per gram of tissue] may be described by different--often complicated--functional forms. Because of the need to readily compare sequences of engineered radiopharmaceuticals, it is efficient to use m
Publikováno v:
Radiation Physics and Chemistry. 49:509-513
The one group approximation employing oppositely directed vector fluences is applied to the problem of a plane source of 32 P located at the interface between two different media. The calculated results are compared with experimental observations. Pr
Publikováno v:
Medical Physics. 20:1243-1250
Beta‐ray dose backscatter factors or dose ratios at planar soft‐tissue boundaries were calculated using the EGS4/PRESTA and CYLTRAN (version 2.1) Monte Carlo codes and these data were compared with experimental results. Since the beta‐ray sourc
Publikováno v:
Applied Radiation and Isotopes. 44:783-787
The spatial dose-rate distribution arising from a unit activity point source of 194Ir embedded in an infinite water medium has been calculated. These results may prove to be both useful and timely, 194Ir is a beta-particle-emitting radionuclide that
Autor:
Peter K. Leichner, Cheuk S. Kwok
Publikováno v:
Medical Physics. 20:529-534
Calculational methods of beta-particle dosimetry in radioimmunotherapy (RIT) are reviewed for clinical and experimental studies and computer modeling of tumors. In clinical studies, absorbed-dose estimates are usually based on the in-vivo quantitatio
Publikováno v:
Medical Physics. 20:223-231
Beta‐ray dose backscatter factors with respect to soft tissue were measured using an extrapolation chamber. The beta‐ray dose backscatter factor is a measure of the change effected in absorbed dose to a soft‐tissue medium when part of the mediu
Publikováno v:
Medical Physics. 18:1181-1191
The energy-averaged transport model for the calculation of dose rate distributions is applied to uniform, spherical source distributions in homogeneous media for radii smaller than the electron range. The model agrees well with Monte Carlo based calc
Publikováno v:
Medical Physics. 18:533-541
Monte Carlo calculations have previously been performed by Eckerman to evaluate the absorbed fractions of continuous sources of monoenergetic electrons in marrow cavities of human bone. The difference in scattering power of electrons in cortical bone