A systemically administered detoxified TLR4 agonist displays potent antitumor activity and an acceptable tolerance profile in preclinical models.

Autor: Chettab K; INSERM U1052, CNRS UMR 5286, Centre de Recherche en Cancérologie de Lyon, Université de Lyon, Lyon, France.; Hospices Civils de Lyon, Lyon, France., Fitzsimmons C; INSERM U1052, CNRS UMR 5286, Centre de Recherche en Cancérologie de Lyon, Université de Lyon, Lyon, France., Novikov A; HEPHAISTOS-Pharma, Université Paris-Saclay, Orsay, France., Denis M; INSERM U1052, CNRS UMR 5286, Centre de Recherche en Cancérologie de Lyon, Université de Lyon, Lyon, France.; Antinéo, Lyon, France., Phelip C; HEPHAISTOS-Pharma, Université Paris-Saclay, Orsay, France., Mathé D; Antinéo, Lyon, France., Choffour PA; Antinéo, Lyon, France., Beaumel S; INSERM U1052, CNRS UMR 5286, Centre de Recherche en Cancérologie de Lyon, Université de Lyon, Lyon, France., Fourmaux E; INSERM U1052, CNRS UMR 5286, Centre de Recherche en Cancérologie de Lyon, Université de Lyon, Lyon, France., Norca P; INSERM U1052, CNRS UMR 5286, Centre de Recherche en Cancérologie de Lyon, Université de Lyon, Lyon, France., Kryza D; Hospices Civils de Lyon, Lyon, France., Evesque A; Antinéo, Lyon, France., Jordheim LP; INSERM U1052, CNRS UMR 5286, Centre de Recherche en Cancérologie de Lyon, Université de Lyon, Lyon, France., Perrial E; INSERM U1052, CNRS UMR 5286, Centre de Recherche en Cancérologie de Lyon, Université de Lyon, Lyon, France., Matera EL; INSERM U1052, CNRS UMR 5286, Centre de Recherche en Cancérologie de Lyon, Université de Lyon, Lyon, France., Caroff M; HEPHAISTOS-Pharma, Université Paris-Saclay, Orsay, France., Kerzerho J; HEPHAISTOS-Pharma, Université Paris-Saclay, Orsay, France., Dumontet C; INSERM U1052, CNRS UMR 5286, Centre de Recherche en Cancérologie de Lyon, Université de Lyon, Lyon, France.; Hospices Civils de Lyon, Lyon, France.

Publikováno v: Frontiers in immunology [Front Immunol] 2023 May 08; Vol. 14, pp. 1066402. Date of Electronic Publication: 2023 May 08 (Print Publication: 2023).

Calcium Channel Blockers Impair the Antitumor Activity of Anti-CD20 Monoclonal Antibodies by Blocking EGR-1 Induction.

Autor: Spasevska I; Univ Lyon, Université Claude Bernard Lyon 1, INSERM 1052, CNRS 5286, Centre Léon Bérard, Centre de Recherche en Cancérologie de Lyon, Lyon, France., Matera EL; Univ Lyon, Université Claude Bernard Lyon 1, INSERM 1052, CNRS 5286, Centre Léon Bérard, Centre de Recherche en Cancérologie de Lyon, Lyon, France., Chettab K; Univ Lyon, Université Claude Bernard Lyon 1, INSERM 1052, CNRS 5286, Centre Léon Bérard, Centre de Recherche en Cancérologie de Lyon, Lyon, France., Ville J; Univ Lyon, Université Claude Bernard Lyon 1, INSERM 1052, CNRS 5286, Centre Léon Bérard, Centre de Recherche en Cancérologie de Lyon, Lyon, France., Potier-Cartereau M; Inserm/University of Tours U1069, Nutrition-Croissance et Cancer (N2C), Tours, France., Jordheim LP; Univ Lyon, Université Claude Bernard Lyon 1, INSERM 1052, CNRS 5286, Centre Léon Bérard, Centre de Recherche en Cancérologie de Lyon, Lyon, France., Thieblemont C; Hemato-Oncology, Hospital Saint-Louis, APHP, Paris, France., Sahin D; Pharma Development Oncology, F. Hoffmann-La Roche, Basel, Switzerland., Klein C; Roche Pharmaceutical Research and Early Development, Roche Innovation Center, Zurich, Switzerland., Dumontet C; Univ Lyon, Université Claude Bernard Lyon 1, INSERM 1052, CNRS 5286, Centre Léon Bérard, Centre de Recherche en Cancérologie de Lyon, Lyon, France. charles.dumontet@chu-lyon.fr.; Hospices Civils de Lyon, Lyon, France.

Publikováno v: Molecular cancer therapeutics [Mol Cancer Ther] 2020 Nov; Vol. 19 (11), pp. 2371-2381. Date of Electronic Publication: 2020 Aug 26.

Characterization of the diffusion properties of different gadolinium-based MRI contrast agents after ultrasound induced blood–brain barrier permeabilization

Autor: Fowlkes, B, Ghanouni, P, Sanghvi, N, Coussios, C, Lyon, Pc, Gray, M, Mannaris, C, Victor, Mds, Stride, E, Cleveland, R, Carlisle, R, Feng, W, Middleton, M, Gleeson, F, Aubry, J, Pauly, Kb, Moonen, C, Vortman, J, Sharabi, S, Daniels, D, Last, D, Guez, D, Levy, Y, Volovick, A, Grinfeld, J, Rachmilevich, I, Amar, T, Zibly, Z, Mardor, Y, Harnof, S, Plaksin, M, Weissler, Y, Shoham, S, Kimmel, E, Naor, O, Farah, N, Paeng, D, Zhiyuan, X, Snell, J, Quigg, Ah, Eames, M, Jin, C, Everstine, Ac, Sheehan, Jp, Lopes, Bs, Kassell, N, Looi, T, Khokhlova, V, Mougenot, C, Hynynen, K, Drake, J, Slayton, M, Amodei, Rc, Compton, K, Mcnelly, A, Latt, D, Kearney, J, Melodelima, D, Dupre, A, Chen, Y, Perol, D, Vincenot, J, Chapelon, J, Rivoire, M, Guo, W, Ren, G, Shen, G, Neidrauer, M, Zubkov, L, Weingarten, Ms, Margolis, Dj, Lewin, Pa, Mcdannold, N, Sutton, J, Vykhodtseva, N, Livingstone, M, Kobus, T, Zhang, Y, Schwartz, M, Huang, Y, Lipsman, N, Jain, J, Chapman, M, Sankar, T, Lozano, A, Yeung, R, Damianou, C, Papadopoulos, N, Brokman, O, Zadicario, E, Brenner, O, Castel, D, Shih-Ying, W, Grondin, J, Zheng, W, Heidmann, M, Karakatsani, Me, Sánchez, Cjs, Ferrera, V, Konofagou, Ee, Yiannakou, M, Cho, H, Lee, H, Han, M, Choi, J, Lee, T, Ahn, S, Chang, Y, Park, J, Ellens, N, Partanen, A, Farahani, K, Airan, R, Carpentier, A, Canney, M, Vignot, A, Lafon, C, Delattre, J, Idbaih, A, Odéen, H, Bolster, B, Jeong, Ek, Parker, Dl, Gaur, P, Feng, X, Fielden, S, Meyer, C, Werner, B, Grissom, W, Marx, M, Weber, H, Taviani, V, Hargreaves, B, Tanaka, J, Kikuchi, K, Ishijima, A, Azuma, T, Minamihata, K, Yamaguchi, S, Nagamune, T, Sakuma, I, Takagi, S, Santin, Md, Marsac, L, Maimbourg, G, Monfort, M, Larrat, B, François, C, Lehéricy, S, Tanter, M, Samiotaki, G, Wang, S, Acosta, C, Feinberg, Er, Kovacs, Zi, Tsang-Wei, T, Papadakis, Gz, Reid, Wc, Hammoud, Da, Frank, Ja, Kim, S, Jikaria, N, Bresler, M, Qureshi, F, Xia, J, Tsui, P, Liu, H, Plata, Jc, Sveinsson, B, Salgaonkar, Va, Adams, M, Diederich, C, Ozhinsky, E, Bucknor, Md, Rieke, V, Mikhail, A, Severance, L, Negussie, Ah, Wood, B, de Greef, M, Schubert, G, Ries, M, Poorman, Me, Dockery, M, Chaplin, V, Dudzinski, So, Spears, R, Caskey, C, Giorgio, T, Costa, Mm, Papaevangelou, E, Shah, A, Rivens, I, Box, C, Bamber, J, ter Haar, G, Burks, Sr, Nagle, M, Nguyen, B, Milo, B, Nhan M., L, Song, S, Zhou, K, Nabi, G, Huang, Z, Ben-Ezra, S, Rosen, S, Mihcin, S, Strehlow, J, Karakitsios, I, Nhan, L, Schwenke, M, Demedts, D, Prentice, P, Haase, S, Preusser, T, Melzer, A, Mestas, J, Chettab, K, Gomez, Gs, Dumontet, C, Werle, B, Marquet, F, Bour, P, Vaillant, F, Amraoui, S, Dubois, R, Ritter, P, Haïssaguerre, M, Hocini, M, Bernus, O, Quesson, B, Livneh, A, Adam, D, Robin, J, Arnal, B, Fink, M, Pernot, M, Khokhlova, Td, Schade, Gr, Wang, Y, Kreider, W, Simon, J, Starr, F, Karzova, M, Maxwell, A, Bailey, Mr, Lundt, Je, Allen, Sp, Sukovich, Jr, Hall, T, Zhen, X, May, P, Lin, Dw, Constans, C, Deffieux, T, Park, E, Ahn, Yd, Kang, Sy, Park, D, Lee, Jy, Vidal-Jove, J, Perich, E, Ruiz, A, Jaen, A, Eres, N, del Castillo, Ma, Myers, R, Kwan, J, Coviello, C, Rowe, C, Crake, C, Finn, S, Jackson, E, Pouliopoulos, A, Caiqin, L, Tinguely, M, Tang, M, Garbin, V, Choi, Jj, Folkes, L, Stratford, M, Nwokeoha, S, Tong, L, Farr, N, D’Andrea, S, Gravelle, K, Chen, H, Lee, D, Hwang, Jh, Tardoski, S, Ngo, J, Gineyts, E, Roux, J, Clézardin, P, Conti, A, Magnin, R, Gerstenmayer, M, Lux, F, Tillement, O, Mériaux, S, Penna, Sd, Romani, Gl, Dumont, E, Sun, T, Power, C, Miller, E, Sapozhnikov, O, Tsysar, S, Yuldashev, Pv, Svet, V, Dongli, L, Pellegrino, A, Petrinic, N, Siviour, C, Jerusalem, A, Cunitz, Bw, Dunmire, B, Inserra, C, Guedra, M, Mauger, C, Gilles, B, Solovchuk, M, Sheu, Twh, Thiriet, M, Zhou, Y, Neufeld, E, Baumgartner, C, Payne, D, Kyriakou, A, Kuster, N, Xiao, X, Mcleod, H, Dillon, C, Payne, A, Khokhova, Va, Sinilshchikov, I, Andriyakhina, Y, Rybyanets, A, Shvetsova, N, Berkovich, A, Shvetsov, I, Shaw, Cj, Civale, J, Giussani, D, Lees, C, Ozenne, V, Toupin, S, Salgaonkar, V, Kaye, E, Monette, S, Maybody, M, Srimathveeravalli, G, Solomon, S, Gulati, A, Bezzi, M, Jenne, Jw, Lango, T, Müller, M, Sat, G, Tanner, C, Zangos, S, Günther, M, Dinh, Ah, Niaf, E, Bratan, F, Guillen, N, Souchon, R, Lartizien, C, Crouzet, S, Rouviere, O, Han, Y, Payen, T, Palermo, C, Sastra, S, Olive, K, van Breugel, Jm, van den Bosch, Ma, Fellah, B, Le Bihan, D, Hernandez-Garcia, L, Cain, Ca, Lyka, E, Elbes, D, Chunhui, L, Tamano, S, Jimbo, H, Yoshizawa, S, Fujiwara, K, Itani, K, Umemura, S, Stoianovici, D, Zaini, Z, Takagi, R, Zong, S, Watkins, R, Pascal-Tenorio, A, Jones, P, Butts-Pauly, K, Bouley, D, Lin, C, Hsieh, H, Wei, K, Garnier, C, Renault, G, Seifabadi, R, Wilson, E, Eranki, A, Kim, P, Lübke, D, Huber, P, Georgii, J, Dresky, Cv, Haller, J, Yarmolenko, P, Sharma, K, Celik, H, Guofeng, L, Qiu, W, Zheng, H, Tsai, M, Chu, P, Webb, T, Vyas, U, Walker, M, Zhong, J, Waspe, Ac, Hodaie, M, Yang, F, Huang, S, Zur, Y, Assif, B, Aurup, C, Kamimura, H, Carneiro, Aa, Rothlübbers, S, Schwaab, J, Houston, G, Azhari, H, Weiss, N, Sosna, J, Goldberg, Sn, Barrere, V, Jang, Kw, Lewis, B, Wang, X, Suomi, V, Edwards, D, Larrabee, Z, Hananel, A, Rafaely, B, Debbiny, Re, Dekel, Cz, Assa, M, Menikou, G, Mouratidis, P, Pineda-Pardo, Ja, de Pedro, Mda, Martinez, R, Hernandez, F, Casas, S, Oliver, C, Pastor, P, Vela, L, Obeso, J, Greillier, P, Zorgani, A, Catheline, S, Solovov, V, Vozdvizhenskiy, Mo, Orlov, Ae, Chueh-Hung, W, Sun, M, Shih, Tt, Chen, W, Prieur, F, Pillon, A, Cartron, V, Cebe, P, Chansard, N, Lafond, M, Seya, Pm, Bera, J, Boissenot, T, Fattal, E, Bordat, A, Chacun, H, Guetin, C, Tsapis, N, Maruyama, K, Unga, J, Suzuki, R, Fant, C, Rogez, B, Afadzi, M, Myhre, Of, Vea, S, Bjørkøy, A, Yemane, Pt, van Wamel, A, Berg, S, Hansen, R, Angelsen, B, Davies, C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3667::5e9b9733977801b2d12c8733363a3cce
http://hdl.handle.net/2108/292561

Transcriptional and Metabolic Investigation in 5'-Nucleotidase Deficient Cancer Cell Lines.

Autor: Cadassou O; Univ Lyon, Université Claude Bernard Lyon 1, INSERM 1052, CNRS 5286, Centre Léon Bérard, Centre de Recherche en Cancérologie de Lyon, 69008 Lyon, France., Forey P; Univ Lyon, Université Claude Bernard Lyon 1, INSERM 1052, CNRS 5286, Centre Léon Bérard, Centre de Recherche en Cancérologie de Lyon, 69008 Lyon, France., Machon C; Univ Lyon, Université Claude Bernard Lyon 1, INSERM 1052, CNRS 5286, Centre Léon Bérard, Centre de Recherche en Cancérologie de Lyon, 69008 Lyon, France.; Hospices Civils de Lyon, Centre Hospitalier Lyon-Sud, 69495 Pierre Bénite, France., Petrotto E; Univ Lyon, Université Claude Bernard Lyon 1, INSERM 1052, CNRS 5286, Centre Léon Bérard, Centre de Recherche en Cancérologie de Lyon, 69008 Lyon, France.; Dipartimento di Biologia, Unità di Biochimica, Università di Pisa, Via San Zeno 51, 56127 Pisa, Italy., Chettab K; Univ Lyon, Université Claude Bernard Lyon 1, INSERM 1052, CNRS 5286, Centre Léon Bérard, Centre de Recherche en Cancérologie de Lyon, 69008 Lyon, France., Tozzi MG; Dipartimento di Biologia, Unità di Biochimica, Università di Pisa, Via San Zeno 51, 56127 Pisa, Italy., Guitton J; Univ Lyon, Université Claude Bernard Lyon 1, INSERM 1052, CNRS 5286, Centre Léon Bérard, Centre de Recherche en Cancérologie de Lyon, 69008 Lyon, France.; Hospices Civils de Lyon, Centre Hospitalier Lyon-Sud, 69495 Pierre Bénite, France., Dumontet C; Univ Lyon, Université Claude Bernard Lyon 1, INSERM 1052, CNRS 5286, Centre Léon Bérard, Centre de Recherche en Cancérologie de Lyon, 69008 Lyon, France.; Hospices Civils de Lyon, Centre Hospitalier Lyon-Sud, 69495 Pierre Bénite, France., Cros-Perrial E; Univ Lyon, Université Claude Bernard Lyon 1, INSERM 1052, CNRS 5286, Centre Léon Bérard, Centre de Recherche en Cancérologie de Lyon, 69008 Lyon, France., Jordheim LP; Univ Lyon, Université Claude Bernard Lyon 1, INSERM 1052, CNRS 5286, Centre Léon Bérard, Centre de Recherche en Cancérologie de Lyon, 69008 Lyon, France.

Publikováno v: Cells [Cells] 2021 Oct 28; Vol. 10 (11). Date of Electronic Publication: 2021 Oct 28.

Impact on Human Health of Salmonella spp. and Their Lipopolysaccharides: Possible Therapeutic Role and Asymptomatic Presence Consequences.

Autor: Mikołajczyk, Mateusz¹ (AUTHOR) matmateusza@gmail.com, Złotkowska, Dagmara² (AUTHOR) d.zlotkowska@pan.olsztyn.pl, Mikołajczyk, Anita³ (AUTHOR) anita.mikolajczyk@uwm.edu.pl

Publikováno v: International Journal of Molecular Sciences. Nov2024, Vol. 25 Issue 22, p11868. 15p.