Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Chetana Sachidanandan"'
Autor:
Shweta Verma, Sujit Dalabehera, Ranjeet Maurya, Dayanidhi Singh, Bhavana Prasher, Rajesh Pandey, Sharmila Bapat, Sivaprakash Ramalingam, Chetana Sachidanandan
Publikováno v:
Stem Cell Research, Vol 78, Iss , Pp 103456- (2024)
Rubinstein Taybi Syndrome (RSTS) is a rare genetic disorder which is caused by mutations in either CREBBP or EP300. RSTS with mutations in CREBBP is known as RSTS-1. We have generated an induced pluripotent stem cell (iPSC) line, IGIBi018-A from an I
Externí odkaz:
https://doaj.org/article/f56e9f250aee4719b19b365bc52e9f1e
Autor:
Bilal Ahmad Lone, Fouzia Siraj, Ira Sharma, Shweta Verma, Shibendra Kumar Lal Karna, Faiz Ahmad, Preeti Nagar, Chetana Sachidanandan, Yuba Raj Pokharel
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-24 (2023)
Abstract Breast cancer is one of the most common cancers with a high mortality rate, underscoring the need to identify new therapeutic targets. Here we report that non-POU domain-containing octamer-binding (NONO) protein is overexpressed in breast ca
Externí odkaz:
https://doaj.org/article/8d08b099fd63438ba0476a8e69b8cc8e
Autor:
Sagar Mahale, Megha Kumar, Amit Sharma, Aswini Babu, Shashi Ranjan, Chetana Sachidanandan, Sivaram V. S. Mylavarapu
Publikováno v:
Scientific Reports, Vol 6, Iss 1, Pp 1-16 (2016)
Abstract Cytoplasmic dynein 1 is a multi-protein intracellular motor essential for mediating several mitotic functions, including the establishment of proper spindle orientation. The functional relevance and mechanistic distinctions between two discr
Externí odkaz:
https://doaj.org/article/f8dcadbb665b4656a8290ae5ae5ba831
Publikováno v:
PLoS ONE, Vol 4, Iss 11, p e7996 (2009)
Vertebrate segmentation is regulated by the "segmentation clock", which drives cyclic expression of several genes in the caudal presomitic mesoderm (PSM). One such gene is Lunatic fringe (Lfng), which encodes a modifier of Notch signalling, and which
Externí odkaz:
https://doaj.org/article/dc7ae9225a194742af4bfd9ca5426311
Publikováno v:
PLoS ONE, Vol 3, Iss 4, p e1947 (2008)
Small molecules have played an important role in delineating molecular pathways involved in embryonic development and disease pathology. The need for novel small molecule modulators of biological processes has driven a number of targeted screens on l
Externí odkaz:
https://doaj.org/article/c69f980f80274c728606f1ead64457bd
Publikováno v:
Chemical Research in Toxicology. 35:1393-1399
The use of many essential drugs is restricted due to their deleterious effects on the liver. Molecules that can prevent or protect the liver from drug-induced liver injury (DILI) would be invaluable in such situations. We used a transgenic line in ze
Autor:
Bilal Ahmad Lone, Fouzia Siraj, Ira Sharma, Shweta Verma, Shibendra Kumar Lal Karna, Faiz Ahmad, Preeti Nagar, Chetana Sachidanandan, Yuba Raj Pokharel
Breast cancer is one of the most common cancers with high mortality, highlighting the vital need to identify new therapeutic targets. Here we report that Non-POU Domain-Containing Octamer-Binding (NONO) Protein is overexpressed in breast cancers and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31fe8ad6f4e8b50d3f231d5f9bf6530f
https://doi.org/10.21203/rs.3.rs-2319552/v1
https://doi.org/10.21203/rs.3.rs-2319552/v1
Autor:
Monika Verma, Niraj Rajesh Bhatt, Aseem Chaphalkar, Kriti Verma, Shreyansh Umale, Shweta Verma, Chetana Sachidanandan, Kausik Chakraborty
Redox homeostasis is an integral part of many cellular processes, and its perturbation is associated with conditions such as diabetes, aging, and neurodegenerative disorders. Redox homeostasis or redox potential in organelles is maintained within a p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71e75f9dab162a22c6c3b5702d391045
https://doi.org/10.1101/2022.02.12.480199
https://doi.org/10.1101/2022.02.12.480199
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1868:159246
Non-alcoholic Fatty Liver Disease (NAFLD) or pathological hepatic lipid overload, is considered to affect obese individuals. However, NAFLD in lean individuals is prevalent, especially in South Asian population. The pathophysiology of lean NAFLD is n
Autor:
Shantanu Sengupta, Sheetal Gandotra, Rijith Jayarajan, Sridhar Sivasubbu, Dhanasekaran Shanmugam, Rajni Yadav, Manoj Kumar Singh, Sindhuri Upadrasta, Vinod Scaria, Shalimar, Swati Varshney, Chetana Sachidanandan, Archana Singh
BACKGROUND AND AIMSInflammation is a constant in Non-Alcoholic Fatty Liver Disease (NAFLD) and is usually considered a consequence. We propose that inflammation can be a cause for NAFLD. Obesity is strongly associated with (NAFLD), but not always. NA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f9d14c18f82b205e3f443c154d7ed88
https://doi.org/10.1101/2020.07.04.162008
https://doi.org/10.1101/2020.07.04.162008