Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Chetan Deshpande"'
Autor:
Debu Tripathy, Zhe Zhang, Joanne L. Blum, Meghan S. Karuturi, Steven L. McCune, Bijoy Telivala, Shailendra Lakhanpal, Kamal Patel, Richard C. Frank, Kit Lu, Chetan Deshpande, Yao Wang, Yuan Liu, Aditya Bardia
Publikováno v:
Cancer Research. 82:P1-18
Background: POLARIS is a prospective, real-world study of palbociclib in patients with hormone receptor-positive (HR+)/human epidermal growth factor receptor 2-negative (HER2–) advanced breast cancer (ABC) in the United States and Canada. These ana
Autor:
Debu Tripathy, Joanne L. Blum, Shibing Deng, Steven L. McCune, Kamal Patel, Yao Wang, Shailendra Lakhanpal, Meghan S. Karuturi, Zhe Zhang, Chetan Deshpande, Monica Z. Montelongo, Eric Gauthier, Yuan Liu, Gabrielle B. Rocque, Aditya Bardia
Publikováno v:
Cancer Research. 83:P5-02
Background: POLARIS is a prospective, real-world study of palbociclib in patients with hormone receptor–positive (HR+)/human epidermal growth factor receptor 2–negative (HER2–) advanced breast cancer (ABC) in the United States and Canada. We pr
Autor:
Sibylle Loibl, Carsten Denkert, Yuan Liu, Erik S. Knudsen, Angela DeMichele, Zhe Zhang, Julia Teply-Szymanski, Martin Filipits, Peter A. Fasching, Michael Gnant, Shibing Deng, Marija Balic, Federico Rojo, Mark Watson, Chetan Deshpande, Nicholas Turner, Otto Metzger, Kathy Puyana Theall, Agnieszka Witkiewicz, Olga Valota, W. Fraser Symmans, Erica L. Mayer
Publikováno v:
Cancer Research. 83:PD17-05
Background: The PENELOPE-B (NCT01864746) and PALLAS (NCT02513394) trials are large prospective, randomized, phase III trials that evaluated adjuvant palbociclib (PAL) + endocrine treatment (ET) vs ET in patients with hormone receptor–positive/human
Autor:
Alex Cordero, Eva M. Trinidad, William C. Dougall, Chetan Deshpande, Eva González-Suárez, Jordi Serra-Musach, Pasquale Pellegrini, Miguel Angel Pujana, Adrián Sanz-Moreno
Publikováno v:
Stem Cells. 34:1027-1039
Prolactin and progesterone both orchestrate the proliferation and differentiation of the mammary gland during gestation. Differentiation of milk secreting alveoli depends on the presence of prolactin receptor, the downstream Jak2-Stat5 pathway and th
Autor:
Robert D. Zura, Sami Mardam-Bey, John Boling, Chetan Deshpande, Maria Manson, Jonathan Godin, Chris Brown, Steven A. Olson
Publikováno v:
Current Orthopaedic Practice. 26:387-394
Autor:
Tao Osgood, Julie A. Lofgren, Marc Payton, Rebecca Robertson, Sean Caenepeel, Dongyin Yu, Jude Canon, Cheng Su, Adrie Jones, Jebediah Ledell, Chetan Deshpande, Jonathan D. Oliner, Xiaoning Zhao, Paul E. Hughes, Anne Y. Saiki
Publikováno v:
Oncotarget
While MDM2 inhibitors hold great promise as cancer therapeutics, drug resistance will likely limit their efficacy as single agents. To identify drug combinations that might circumvent resistance, we screened for agents that could synergize with MDM2
Autor:
Nicholas Beckloff, Chetan Deshpande, Mark J. Ruoff, Conor Dunn, Donald Hohman, Dipak V. Patel, Michael Faloon
Publikováno v:
Journal of long-term effects of medical implants. 25(4)
Vertebral compression fractures are a significant source of morbidity and mortality among patients of all age groups. These fractures result in both acute and chronic pain. Patients who sustain such fractures are known to suffer from more comorbiditi
Autor:
Matteo Pellegrini, Michael A. Teitell, Jason S. Hong, Nicholas A. Cacalano, Chetan Deshpande, John P. Manis, Richard A. Gatti, Michael A. Damore, Ali I. Kuraishy, Mara H. Sherman
Publikováno v:
Molecular Cell. 39(6):873-885
During an immune response, B cells undergo rapid proliferation and activation-induced cytidine deaminase (AID)-dependent remodeling of immunoglobulin (IG) genes within germinal centers (GCs) to generate memory B and plasma cells. Unfortunately, the g
Autor:
Yue Sun, Elizabeth D. Mellins, Tzielan Lee, Ann B. Begovich, Claudia Macaubas, Jane L. Park, Sheng Yung Chang, Shivani Srivastava, Heather C. Alexander, Chetan Deshpande
Publikováno v:
Clinical Immunology. 136:257-268
We investigated whether circulating monocytes from patients with systemic juvenile idiopathic arthritis (SJIA) are resistant to apoptosis and which apoptotic pathway(s) may mediate this resistance. A microarray analysis of peripheral blood mononuclea
Autor:
Elizabeth D. Mellins, Carolyn M. Phillips, Tzielan Lee, Christy Sandborg, Jane L. Park, Chetan Deshpande, Claudia Macaubas, Ariana Peck, Khoa D. Nguyen
Publikováno v:
Clinical Immunology. 134:206-216
Juvenile idiopathic arthritis (JIA) encompasses a group of chronic childhood arthritides of unknown etiology. One subtype, systemic JIA (SJIA), is characterized by a combination of arthritis and systemic inflammation. Its systemic nature suggests tha