Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Chetan Chitnis"'
Autor:
Isabel Byrne, Timothy William, Tock H. Chua, Catriona Patterson, Tom Hall, Mark Tan, Chetan Chitnis, John Adams, Susheel K. Singh, Lynn Grignard, Kevin K. A. Tetteh, Kimberly M. Fornace, Chris J. Drakeley
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Malaysia has reported no indigenous cases of P. falciparum and P. vivax for over 3 years. When transmission reaches such low levels, it is important to understand the individuals and locations where exposure risks are high, as they may be at
Externí odkaz:
https://doaj.org/article/a7bfd19017534ba6b1692f317f514ff5
Autor:
Glória Matambisso, Nanna Brokhattingen, Sónia Maculuve, Pau Cisteró, Henriques Mbeve, Anna Escoda, Judice Miguel, Elena Buetas, Ianthe de Jong, Boaventura Cuna, Cardoso Melembe, Nelo Ndimande, Gemma Porras, Haily Chen, Kevin K. A. Tetteh, Chris Drakeley, Benoit Gamain, Chetan Chitnis, Virander Chauhan, Llorenç Quintó, Beatriz Galatas, Eusébio Macete, Alfredo Mayor
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-12 (2022)
Abstract Background Low-density Plasmodium falciparum infections prevail in low transmission settings, where immunity is expected to be minimal, suggesting an immune-independent effect on parasite densities. We aimed to describe parasite densities in
Externí odkaz:
https://doaj.org/article/8482e32ae99a4b09a14169cc03cfcd21
Autor:
Henry Surendra, Supargiyono, Riris A. Ahmad, Rizqiani A. Kusumasari, Theodola B. Rahayujati, Siska Y. Damayanti, Kevin K. A. Tetteh, Chetan Chitnis, Gillian Stresman, Jackie Cook, Chris Drakeley
Publikováno v:
BMC Medicine, Vol 18, Iss 1, Pp 1-14 (2020)
Abstract Background In order to improve malaria burden estimates in low transmission settings, more sensitive tools and efficient sampling strategies are required. This study evaluated the use of serological measures from repeated health facility-bas
Externí odkaz:
https://doaj.org/article/e7cb738894d4469c8dc0bc6e57d2e37a
Autor:
Carlota Dobaño, Itziar Ubillos, Chenjerai Jairoce, Ben Gyan, Marta Vidal, Alfons Jiménez, Rebeca Santano, David Dosoo, Augusto J. Nhabomba, Aintzane Ayestaran, Ruth Aguilar, Nana Aba Williams, Núria Díez-Padrisa, David Lanar, Virander Chauhan, Chetan Chitnis, Sheetij Dutta, Deepak Gaur, Evelina Angov, Kwaku Poku Asante, Seth Owusu-Agyei, Clarissa Valim, Benoit Gamain, Ross L. Coppel, David Cavanagh, James G. Beeson, Joseph J. Campo, Gemma Moncunill
Publikováno v:
BMC Medicine, Vol 17, Iss 1, Pp 1-19 (2019)
Abstract Background Vaccination and naturally acquired immunity against microbial pathogens may have complex interactions that influence disease outcomes. To date, only vaccine-specific immune responses have routinely been investigated in malaria vac
Externí odkaz:
https://doaj.org/article/b537671e318343a6a6e9016896cf4fdc
Autor:
Ramin Mazhari, Jessica Brewster, Rich Fong, Caitlin Bourke, Zoe S J Liu, Eizo Takashima, Takafumi Tsuboi, Wai-Hong Tham, Matthias Harbers, Chetan Chitnis, Julie Healer, Maria Ome-Kaius, Jetsumon Sattabongkot, James Kazura, Leanne J Robinson, Christopher King, Ivo Mueller, Rhea J Longley
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0238010 (2020)
Multiplexed bead-based assays that use Luminex® xMAP® technology have become popular for measuring antibodies against proteins of interest in many fields, including malaria and more recently SARS-CoV-2/COVID-19. There are currently two formats that
Externí odkaz:
https://doaj.org/article/b5f8d5edbb2241afbb878a444176817b
Autor:
Itziar Ubillos, Alfons Jiménez, Marta Vidal, Paul W. Bowyer, Deepak Gaur, Sheetij Dutta, Benoit Gamain, Ross Coppel, Virander Chauhan, David Lanar, Chetan Chitnis, Evelina Angov, James Beeson, David Cavanagh, Joseph J. Campo, Ruth Aguilar, Carlota Dobaño
Publikováno v:
Malaria Journal, Vol 17, Iss 1, Pp 1-15 (2018)
Abstract Background The quantitative suspension array technology (qSAT) is a useful platform for malaria immune marker discovery. However, a major challenge for large sero-epidemiological and malaria vaccine studies is the comparability across labora
Externí odkaz:
https://doaj.org/article/5ba8377aef2545d38add042e560f8738
Autor:
Aida Valmaseda, Quique Bassat, Pedro Aide, Pau Cisteró, Alfons Jiménez, Aina Casellas, Sonia Machevo, Ruth Aguilar, Betuel Sigaúque, Virander S. Chauhan, Christine Langer, James Beeson, Chetan Chitnis, Pedro L. Alonso, Deepak Gaur, Alfredo Mayor
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract Plasmodium falciparum proteins involved in erythrocyte invasion are main targets of acquired immunity and important vaccine candidates. We hypothesized that anti-parasite immunity acquired upon exposure would limit invasion-related gene (IRG
Externí odkaz:
https://doaj.org/article/9da294e70b2248cc902b62b89b355640
Autor:
Carlota Dobaño, Rebeca Santano, Marta Vidal, Alfons Jiménez, Chenjerai Jairoce, Itziar Ubillos, David Dosoo, Ruth Aguilar, Nana Aba Williams, Núria Díez-Padrisa, Aintzane Ayestaran, Clarissa Valim, Kwaku Poku Asante, Seth Owusu-Agyei, David Lanar, Virander Chauhan, Chetan Chitnis, Sheetij Dutta, Evelina Angov, Benoit Gamain, Ross L. Coppel, James G. Beeson, Linda Reiling, Deepak Gaur, David Cavanagh, Ben Gyan, Augusto J. Nhabomba, Joseph J. Campo, Gemma Moncunill
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Naturally acquired immunity (NAI) to Plasmodium falciparum malaria is mainly mediated by IgG antibodies but the subclasses, epitope targets and effector functions have not been unequivocally defined. Dissecting the type and specificity of antibody re
Externí odkaz:
https://doaj.org/article/32aa5029682c4bfd9b0f38f363686bb5
Autor:
Camila Tenorio França, Michael T White, Wen-Qiang He, Jessica B Hostetler, Jessica Brewster, Gabriel Frato, Indu Malhotra, Jakub Gruszczyk, Christele Huon, Enmoore Lin, Benson Kiniboro, Anjali Yadava, Peter Siba, Mary R Galinski, Julie Healer, Chetan Chitnis, Alan F Cowman, Eizo Takashima, Takafumi Tsuboi, Wai-Hong Tham, Rick M Fairhurst, Julian C Rayner, Christopher L King, Ivo Mueller
Publikováno v:
eLife, Vol 6 (2017)
The study of antigenic targets of naturally-acquired immunity is essential to identify and prioritize antigens for further functional characterization. We measured total IgG antibodies to 38 P. vivax antigens, investigating their relationship with pr
Externí odkaz:
https://doaj.org/article/98417d5e38f3439da6e552ae20919fe9
Autor:
Azucena Bardají, Flor Ernestina Martínez-Espinosa, Myriam Arévalo-Herrera, Norma Padilla, Swati Kochar, Maria Ome-Kaius, Camila Bôtto-Menezes, María Eugenia Castellanos, Dhanpat Kumar Kochar, Sanjay Kumar Kochar, Inoni Betuela, Ivo Mueller, Stephen Rogerson, Chetan Chitnis, Dhiraj Hans, Michela Menegon, Carlo Severini, Hernando Del Portillo, Carlota Dobaño, Alfredo Mayor, Jaume Ordi, Mireia Piqueras, Sergi Sanz, Mats Wahlgren, Laurence Slutsker, Meghna Desai, Clara Menéndez, PregVax Study Group
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 6, p e0005606 (2017)
Despite that over 90 million pregnancies are at risk of Plasmodium vivax infection annually, little is known about the epidemiology and impact of the infection in pregnancy.We undertook a health facility-based prospective observational study in pregn
Externí odkaz:
https://doaj.org/article/a2e52984632e429abd1694573b68e119